Term
Since Pathogenic Parasites rely on their hosts for survival, the population dynamics of the parasite are influenced by the population dynamics of the hosts. The host population will likely contain which of the following? |
|
Definition
a. individuals who are susceptible b. individuals who are infected c. individuals who have been infected but have never recovered *d. all of the above |
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Term
While an {_______} lives mainly on the surface of its host, an {________} lives mainly in the body of its host. |
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Definition
ectoparasite, endoparasite |
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Term
What constitutes an epidemic? |
|
Definition
a. 25 outbreaks b. 50 outbreaks c. 1 outbreak d. 10 outbreaks *e. all of the above |
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Term
Elevated levels of which immune cells indicate a worm infection? |
|
Definition
a. basophils b. eosinophils |
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Term
A disease involving a parasite that has accidentally infected a human; the normal host for the parasite is an animal. |
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Definition
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Term
Hemoflagellates are transmitted by which organisms? |
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Definition
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Term
The family Trypanosomatidae, contain two genera that parasitize humans, which are Genus Leishmania and Genus Trypanosoma. |
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Definition
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Term
Which is not a form of transformation that is undergone by Leishmania? |
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Definition
*B. Use of amino acids as a nitrogen source |
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Term
Leishmania parasites enter cells by {__________}. |
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Definition
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Term
Of the three developmental stages in ticks, which stage is the most significant in human infection? |
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Definition
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Term
Which one of these is NOT a natural host resistance to Plasmodium infections? |
|
Definition
*e. Fructose-6-phosphate deficiency |
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Term
The cysts of Balantidium coli have cilia. |
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Definition
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Term
Giardia lambilia replicates via a process called longitudinal binary fission. |
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Definition
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Term
Vector(s) of Chagas disease include which of the following. (HINT: Recognize the difference between a vector and the actual parasite which causes the disease) |
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Definition
b. Triatoma infestans c. Rhodnius prolixus *d. B and C |
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Term
In Kinetoplastids RNA editing is the process of postranscriptional sequence alteration via {_______} or {_____} of uridylate residues at specific sites of Mitochondrial RNA. |
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Definition
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Term
Acute Chagas disease is mostly found in: |
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Definition
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Term
What is the main downfall to using a blood smear to diagnose a T.cruzi infection? |
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Definition
*b. Can only find parasites in blood during acute phases of disease |
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Term
Trypanosoma cruzi is found only in |
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Definition
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Term
Which of the following is true of Trypanosoma cruzi? |
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Definition
*d. The vector is the Reduviid bug |
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Term
The West Nile Virus only infects the human species. |
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Definition
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Term
[_____] is the vector responsible for "sleeping sickness." |
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Definition
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Term
Mucosal Leishmaniasis are primary lesions of the mucous memebranes such as the nose and oral cavity |
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Definition
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Term
All of the following are differences between slender and stumpy trypomastigotes, except |
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Definition
*d. cytoskeleton composition |
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Term
T. cruzi is the causative agent of {______} disease |
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Definition
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Term
T. cruzi parasites are ONLY found in the Americas--if a person is infected with them, they can't have acquired it from any other place in the world. |
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Definition
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Term
In the fourth morphological form among hemoflagellates, many types of polymorphism are exhibited. These are |
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Definition
a. long, slender trypomastigote b. stumpy trypomastigote *d. a & b |
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Term
In Plasmodium, the asexual phase [_____], occurs in the human, whereas the sexual phase [______], occurs in the mosquito |
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Definition
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Term
Which of the following parasitic stages is characterized by asexual division? |
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Definition
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Term
Which alteration of the vagina will help treat T. vaginalis? |
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Definition
*a. Lowering the pH to 4.5 |
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Term
The metronidazole drug used to treat T. vaginalis forms an intermediate that is toxic, damaging DNA and other macromolecules. |
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Definition
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Term
How would one describe the parasites of T. vaginalis when observed in a wet mount? |
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Definition
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Term
What structure in Trichomonas resemble the mitochondria? |
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Definition
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Term
How does T. vaginalis change the pH of the vagina? |
|
Definition
*b. It makes it more alkaline |
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Term
Infection of T. vaginalis in women is seen less if: |
|
Definition
*b. They use oral contraceptives |
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Term
Men are assymptomatic carriers of Trichomonas vaginalis. |
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Definition
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Term
The trophozoites of Trichomonas species are very active and motile. |
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Definition
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Term
Dientamoeba fragilis is not invasive. |
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Definition
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Term
Giardia produces an IgA [____] |
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Definition
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Term
Giardia lamblia infection is commonly seen in: |
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Definition
a. Children 6-10 years of age b. Daycare centers c. Homosexual males d. Wilderness campers *e. All of the above |
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Term
What gives the feces of individuals infected with Giardia lamblia its distinctive smell? |
|
Definition
*c. The layer of fat present |
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Term
If you let feces of an individual with Giardia lamblia settle, a layer of fat will become apparent. |
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Definition
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Term
Maturing cysts in Giardia lamblia gain: |
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Definition
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Term
Cysts are the site of nuclear division in Giardia lamblia. |
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Definition
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Term
The entire life span of the four species of Plasmodium that infect humans is spent in two hosts: the female mosquito insect vector and a human host. |
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Definition
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Term
This complex of organelles are found in the sporozoite and merozoite stages of the life cycles of these organisms |
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Definition
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Term
Babesiosis, toxoplasmosis, cryptosporidiosis, isosporiasis and cyclosporidiosis belong to the phylum Apicomplexa. |
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Definition
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Term
The "eyes" in Giardia lamblia are its [_____]. |
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Definition
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Term
A fool-proof way to detect infection by an amoeba is through the discovery of cysts in feces. |
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Definition
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Term
[______] results in intermittend watery diarrhea with stools containing mucus and blood. |
|
Definition
*c. Balantidial dysentery |
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|
Term
Which of the following are human reservoirs of Balantidium coli? |
|
Definition
a. Pigs c. Monkeys *e. A and C |
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Term
The cysts of Balantidium coli have cilia. |
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Definition
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|
Term
Balantidium coli undergoes sexual reproduction by [______] |
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Definition
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Term
Balantidium coli undergoes sexual reproduction by [_____] |
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Definition
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Term
[_____] is associated with contamination of contact lens fluid. |
|
Definition
*a. Acanthamoeba keratitis |
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Term
Naegleria fowleri produce sucker-like appendages or [_____] that 'nibble' away at the tissue culture cells. |
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Definition
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Term
High prevalence of antibodies to Naegleria is found in [_____] |
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Definition
*a. young adults in southeastern USA |
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Term
Both trophozoites and cysts are found in Acanthamoeba species. |
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Definition
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Term
Both trophozoites and cysts are found in Naegleria fowleri. |
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Definition
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Term
Free-living amoebas are intestinal blood parasites. |
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Definition
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Term
The American form of trypanosomiasis is caused by Trypanosoma vivax. |
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Definition
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Term
Fluctuations in the number of Trypanosoma brucei gambiense is widely attributed to its ability to vary the chemical composition of its [_____] |
|
Definition
*a. variant surface glycoproteins (VSGs) |
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Term
The infective morophological form of the protozoan Trypanosoma in humans is the______. |
|
Definition
*b. metacyclic trypomastigote |
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Term
In humans, the initial sign of cutaneous leishmaniasis infection is______. |
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Definition
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Term
When the identification of intracellular amastigotes from blood and tissue smears are inconclusive, xenodiagnosis can be used but is often time consuming. |
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Definition
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Term
In a leishmaniasis infection, replacement of infected cells produces hyperplasia and consequent enlargement of visceral organs associated with the system, such as the [______] and [______] |
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Definition
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Term
Which of the following are the three clinical manifestations of Leishmania in humans? |
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Definition
*b. visceral, cutaneous, mucocutaneous |
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Term
The causative agent for visceral leishmaniasis, also known as dumdum fever, or kala-azar, is: |
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Definition
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Term
Leishmaniasis is considered an opportunistic infection and is grouped among those diseases that take advantage of immunocompromised individuals. |
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Definition
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Term
Each of the following statements concerning Trichomonas vaginalis is correct except: |
|
Definition
*d. T. vaginalis causes dysentry |
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Term
In RNA editing in kinetoplastids,what does TUTase stand for? |
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Definition
*b. 3'terminal uridylyl transferase |
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Term
Visceral Leishmaniasis mainly infects the elderly people of Europe. |
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Definition
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Term
What is the correct taxonomy of the parasite T. cruzi from phylum to genus? |
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Definition
*b. Sarcomastigophora, Mastigophora, Kinestoplastida, Trypanosomatidae, Trypanosoma |
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Term
What organelle in the cytoplasm of Protozoa is used mainly for osmoregulation? |
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Definition
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Term
What is the main function of IgE? |
|
Definition
*b. triggering histamine release from mast cells |
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Term
All of the following are characteristics of hemoflagellates except: |
|
Definition
*c. numerous mitochondria |
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Term
The most important question to ask during the differential diagnosis of an infection from T. brucei is: |
|
Definition
*b. Has the patient been to east or west Africa |
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Term
The vector for T. brucei brucei, T. brucei gambiense, and T. brucei rhodesiense is: |
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Definition
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|
Term
What do xenodiagnosis studies show? |
|
Definition
*a. There is communication between parasites and vectors that recruit parasites to feeding vectors |
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Term
The cell-funeral hypothesis explains how: |
|
Definition
*d. T. cruzi infection results in host T cells killing other host cells |
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Term
One of the most significant presentations of Chagas disease, caused by T. cruzi, is: |
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Definition
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|
Term
T.cruzi demonstrates intracellular pathogenesis through lysosome-mediated entry of an infected cell. |
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Definition
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|
Term
Hemoflagellates have cyst forms. |
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Definition
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Term
How do the trypomastigote, epimastigote, promastigote, and amastigote forms differ regarding the overall morphology of the hemoflagellates? |
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Definition
*c. location of kinetoplast relative to nucleus and the single flagellum |
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Term
Along with a kinetoplast, hemoflagellates also have: |
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Definition
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|
Term
What is the difference between the Stercoraria and Salivaria subgenuses of the genus Trypanosoma of the Hemoflagellates? |
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Definition
*a. location of where the parasite develops in the vector |
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Term
The tissue inflammatory response during amoebiasis is initiated and fueled by a combination of human and amoebic factors and ultimately leads to basophil-mediated intestinal destruction. |
|
Definition
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|
Term
Which is true about free living amoeba Naegleira fowleri: |
|
Definition
*a. There is no cyst stage in humans |
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|
Term
Metronidazole is effective against: |
|
Definition
a. worms b. anaerobes c. Giardia *d. all of the above |
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Term
You're attempting to identify a sample of unknown bacteria. You've been told it belongs to the genus Entamoeba, but you still need to determine the species. Looking under a microscope, you see jagged chromosomal bars and nuclei predominately located around the outside. Based on this information, what is this bacteria? |
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Definition
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Term
In regards to Plasmodium falciparum, once the parasite gets into red blood cells and is dividing, what is the duration of the fever free period? |
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Definition
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|
Term
Which of the following is pathogenic under the Sub-order Tubulina? |
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Definition
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|
Term
Metronidazole is a typical drug used to treat visceral protozoa. |
|
Definition
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|
Term
Which of the following is a mode of transmission for amoeba? |
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Definition
a. water b. food-borne *d. a and b |
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Term
Primary amoebic meningoencephalitis (PAM) due to Naegleria fowleri, if diagnosed in time, can be treated with the following: |
|
Definition
*c. intravenous and intrathecal amphotericin B and miconazole, plus rifampin |
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|
Term
An effective way to reduce specific visceral protozoal infection such as E. hystolytica and G. lamblia is to: |
|
Definition
*b. Boil drinking water, add 1.25-3 grams of iodine per liter of water in endemic areas |
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|
Term
Which of the following is not a symptom of Intestinal Disease (Amebic Colitis)? |
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Definition
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|
Term
Ciliates are found in which Phylum? |
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Definition
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|
Term
Ciliates have which kinds of vacuoles? |
|
Definition
a. contractile c. food *d. a and c |
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Term
Naegleria fowleri "nibble" away at cells by means of sucker-like appendages called {________} |
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Definition
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Term
|
Definition
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|
Term
Ionophore-like proteins called {_______} mediate cytolytic and apoptotic effects among epithelial cells and neutrophils. |
|
Definition
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Term
Amoeba-induced inflammations in the intestine leads to {_______}-mediated intestinal destruction. |
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Definition
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|
Term
Immobile parasites can invade the intestine. |
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Definition
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|
Term
Amebic Liver abscess, induced by Trophozoites, is: |
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Definition
*c. destruction of liver cells |
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|
Term
The mucosa of the intestines gets thinner with Amebic Colitis. |
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Definition
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|
Term
Hallmarks of intestinal disease (amebic colitis) include: |
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Definition
a. flask shaped lesions b. diarrhea, dysentery, GI pain *d. a and b |
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Term
|
Definition
a. have 5 free flagellar b. reside in the large intestine c. are thought to be associated with bowel disease *d. all of the above |
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Term
Trichomonas tenax have 4 free flagellar |
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Definition
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|
Term
Backpacker's disease is the popular name of the infection caused by: |
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Definition
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|
Term
Giardia lambia divides by binary fission in the {_________} direction. |
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Definition
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|
Term
Amoebaphore A in Entamoeba histolytica trophozoites cause liver abscesses whereas amoebaphores B and C are the causative agents of amoebic colitis. |
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Definition
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|
Term
All of the following are nonpathogenic flagellates except: |
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Definition
*b. Trichomonas vaginalis |
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Term
Giardia has no mitochondria but can use oxygen when available. |
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Definition
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|
Term
Amoebaphore A in Entamoeba histolytica trophozoites cause liver abscesses whereas amoebaphores B and C are the causative agents of amoebic colitis. |
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Definition
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|
Term
In which morphological form of Entamoeba histolytica is the organism considered pathogenic? |
|
Definition
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|
Term
What are the end products in the metabolization of lactate in Trichomonads? |
|
Definition
a. Formate b. Acetate *d. a and b |
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Term
The carrier state of amoebiasis is known as: |
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Definition
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|
Term
Species in the genus of Trichomonas do not have cysts. |
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Definition
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|
Term
Which of the following species causes malabsorption of fats, fat soluble substances and Vitamin B12? |
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Definition
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|
Term
Which of the following statements is false? |
|
Definition
*d. Tsetse flies lay their eggs in the shallow water, making it easy to find and eliminate their eggs. |
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Term
Which type of cyst from some amoebae parasites, found in humans and domestic animals, contains chromatoidal bars? |
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Definition
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Term
Many protozoa form cysts which are round cytoplasmic masses surrounded by a rigid or semi-rigid cyst wall secreted by an organism. Which of the following is not true of cysts? |
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Definition
*b. The cyst form of an organism is not the infective form of a parasite. |
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|
Term
Biopsy specimens were taken from patients infected with just Naegleria and patients infected with just Acanthamoeba. What is the difference observed between the two different biopsy specimens? |
|
Definition
*d. Both cysts and trophozoites are found in the specimen from patient infected with Acanthamoeba, only trophozoites are found in the specimen from the patient infected with Naegleria, however. |
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|
Term
Which of the following is false about primary amebic meningoencephalitis? |
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Definition
*b. Cysts found in CSF and high neutrophil count. |
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|
Term
Which of the following speicies are free living amoebae? |
|
Definition
*a. Naegleria fowleri and Hartmanella |
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|
Term
Which of the following is false about Entamoeba gingivalis? |
|
Definition
*a. The mature cyst has the size of 15 um. |
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|
Term
The mature cyst of Entamoeba histolytica usually has 8 nuclei. |
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Definition
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|
Term
Which of the following species belong to suborder Tubulina? |
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Definition
*c. Entamoeba histolytica, Entamoeba gingivalis, Iodamoeba buctschlii |
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|
Term
Which of the following species has the biggest size in suborder Tubulina? |
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Definition
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|
Term
Species in sub-phylum Mastigophora use pseudopodia for locomotion. |
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Definition
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|
Term
Species in sub-phylum Sarcodina use flagella for locomotion. |
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Definition
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|
Term
Genitourinary amebiasis is one of the extraintestinal diseases caused by trophozoite- induced cell destruction. |
|
Definition
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|
Term
Which of the following is extraintestinal diseases caused by trophozoites of Entamoeba histolytica? |
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Definition
a. Amebic liver abscess b. Pulmonary Amebiasis c. Brain abscess. *d. All of the above |
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|
Term
The two main functions of Entamoeba histolytica’s mediators of pathogenesis are: |
|
Definition
a. Attachment to host’s epithelia cells in the large intestine, and protection against binding of antibody and attachment b. Attachment to host’s epithelia cells in the large intestine, and protection against phagocytosis by neutrophils. c. Attachment to host’s epithelia cells in the large intestine, and protection against phagocytosis by macrophages. *d. None of the above. |
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|
Term
Which of the following is true about Entamoeba histolytica? |
|
Definition
a. It belongs in the class Lobosea b. It has mitosomes. *d. a and b are correct |
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Term
Non-pathogenic amoeba usually have ________ in their trophozoites. |
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Definition
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|
Term
Which of the following endoparasites is parasite of digestive tract? |
|
Definition
a. Giardia lambia b. Entamoeba histolytica c. Balantidium coli *d. All of the above |
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Term
Intestinal and Urogential Flagellates are members of the phylum: |
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Definition
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|
Term
Giardia requires _______ cysts to establish infection. |
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Definition
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Term
{_________} is the fatty and smelly stool often associated with Giardia. |
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Definition
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|
Term
The incubation period of Giardia is {________}. |
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Definition
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Term
Which of the following is a similarity between prokaryotes and eukaryotes? I. Both share an identical genetic language. II. Both share a common set of membrane-bound organelles. III. Both have plasma membrane of similar construction. IV. Both share common metabolic pathways. |
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Definition
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|
Term
What are some of the symptoms associated with Amebic Colitis? |
|
Definition
a. Gastro-intestinal pain b. Diarrhea c. Weight loss *d. All of the above |
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|
Term
About how much of the world’s population is infected with E. histolytica? |
|
Definition
|
|
Term
What is a main characteristic of Entamoeba coli? |
|
Definition
|
|
Term
What is a unique feature of Entamoeba histolytica? |
|
Definition
*d. Has central nucleolus |
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|
Term
Endodyogeny is a form of endopolyogeny where what is formed? |
|
Definition
|
|
Term
Many protozoa form cysts. |
|
Definition
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|
Term
Which of the following is considered to be the world's most prevalent intestinal parasite? |
|
Definition
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|
Term
One way to distinguish between Entomoeba histolytica and Entomoeba coli is by the number of nuclei, the chromatoidal bars, and the size of the cysts. |
|
Definition
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|
Term
Which genus is pathogenic out of the suborder Tubulina? |
|
Definition
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|
Term
What is commonly found inside pathogenic amoebas? |
|
Definition
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|
Term
{__________} attracts phagocytes to a pathogen. |
|
Definition
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|
Term
Early and late endosomes are distinguished on the basis of what? (Select all that apply) |
|
Definition
*a. Buoyant density *c. pH *d. protein composition |
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|
Term
Which of the following is NOT a host type? |
|
Definition
|
|
Term
Which of the following supports the immature (not fully developed) form of a parasite? |
|
Definition
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|
Term
This cell allows macrophages to engulf foreign particles in the host. {__________} |
|
Definition
|
|
Term
Which is true of the genus Trichomonas? |
|
Definition
a. they have free flagella b. no cyst form c. anatomically site specific *d. these are all true |
|
|
Term
A few components of the innate immune system are macrophages, the lining of internal tracts, secretions, soluble blood proteins, and the skin. |
|
Definition
|
|
Term
Metronidazole is a drug used to treat facultative aerobes such as Giardia and Entamoeba histolytica. |
|
Definition
|
|
Term
Which of the following statements is incorrect? |
|
Definition
*b. Cyst is the main form of transmission |
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|
Term
Which of the following processes can be further studied to develop anti-protozoan drugs? |
|
Definition
*d. The signaling pathway involves that leads to the biosynthesis of cyst wall components. |
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|
Term
What of the following statements is true about protozoa? |
|
Definition
*a. Have encystation that protect it against unfavorable environmental conditions. |
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|
Term
Schizogony is a type of protozoa’s sexual reproduction, and sygany is a type of asexual reproduction. |
|
Definition
|
|
Term
Entamoeba histolytica and Escherichia coli can both have a maximum of 4 nuclei in its cyst form. |
|
Definition
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|
Term
In an archeological dig, you find and unknown organism. You dissect the flagellum and find that the microtubules are arranged in a 9+2 structure. Based on this structure you can conclude that this organism... |
|
Definition
|
|
Term
Which of the following is not a mediator of the pathogenesis of Entamoeba histolytica? |
|
Definition
*d. hard external shell not sensitive to bodily changes |
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|
Term
A patient with Amebiasis complains of gastro-intestinal pain and diarrhea. A stool sample taken from this patient will most likely contain... |
|
Definition
*c. Entamoeba histolytica trophozoites |
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|
Term
Sasha was diagnosed HIV positive 5 years ago. Upon her recent trip to Cabo San Luca, Mexico she returned with diarrhea, nausea and vomiting and dehydration. She also felt muscle cramps and weakness. Her physician prescribed her medication for Cholera, but the symptoms remained. What parasitic infection best described Sasha’s symptomatology? |
|
Definition
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|
Term
As a general rule among flagellates the principle means of locomotion is flagellar, where as among amoeba it is pseudopodial. |
|
Definition
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|
Term
Humans are the definitive host for round worms because humans harbor the reproducing adult roundworms. Depending on the species, the adult female nematode produces either fertilized eggs or Larvae. Which route is incorrect? |
|
Definition
a. Eggs maybe immediately infective by being ingested b. Eggs or larvae may require a period of external development to reach the infective stage c. An insect may transmit eggs or larvae to a new host *d. None of the above |
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|
Term
What distinguishes a pathogenic amoeba from a nonpathogenic is the ability to transform from the cyst form to the trophozoite form: |
|
Definition
|
|
Term
Which of the following is NOT true of Balantidium? |
|
Definition
*d. It is among the smallest members of Protozoa |
|
|
Term
Which of the following parasites causes African sleeping sickness? |
|
Definition
|
|
Term
During pairing of homologous chromosomes,crossover of chromosomes may result in the formation of recombinant. |
|
Definition
|
|
Term
Naegleria is commonly found in fresh water lakes in ponds in Florida and the southern U.S. |
|
Definition
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|
Term
In ciliates, the numerous basal bodies are interconnected by a series of subpellicular [_______] or neurofibrils. |
|
Definition
|
|
Term
Which of the following endoparasites is parasite of digestive tract? |
|
Definition
a. Giardia lamblia b. Entamoeba histolytica c. Balantidium coli *d. All of the above |
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|
Term
Which type of pseudopodia is the most common form among parasitic amoebae? |
|
Definition
|
|
Term
[________] 1. Crescent shaped membrane |
|
Definition
|
|
Term
[________] 2. Rodlike structure that runs along the base of the undulating membrane |
|
Definition
|
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Term
[________] 3. Supporting structure embedded along the longitudinal axis on the cytoplasm |
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Definition
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Term
Which of the following processes does not involve sexual reproduction? |
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Definition
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Term
Endodyogeny is a specialized sexual reproduction involving nuclear exchange and union after cells join. |
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Definition
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Term
Which of the following are true about cysts: I) They are the infective or transmissible form of parasite. II) They protect against unfavorable external environmental conditions. III) They are the site for morphogenesis and nuclear division. |
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Definition
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Term
Which enzymes are located within dynein arms of an axoneme? |
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Definition
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Term
Which of the following protozoans are particularly notorious for causing primary amoebic meningoencephalitis? |
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Definition
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Term
Why is the fatality rate for those infected with Naegleria fowleri so high? |
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Definition
a. Death occurs only a few days after symptoms surface b. Most diagnoses are made post mortem c. Treatment options are few and provide limited effectiveness *d. All of the above |
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Term
During asexual reproduction in Protozoa, the process of fission takes place in which sequence? |
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Definition
*c. organelles, nucleus, cytoplasm |
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Term
Members of the sub-phylum Sarcodina have which characteristic? |
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Definition
*d. usage of pseudopods for locomotion |
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Term
Members of the phylum Sarcomastigophora have: |
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Definition
*c. Flagella and/or Pseudopodia |
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Term
If you encounter an organism that has a macronucleus and a micronucleus, you can tell that you are NOT dealing with a ciliate. |
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Definition
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Term
Well-defined nuclei bounded by nuclear envelopes are characteristic of ALL protozoa. |
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Definition
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Term
How are microtubules within axoneme of motile flagella/cilia organized? |
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Definition
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Term
Balantidium coli is in Phylum {_______} |
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Definition
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Term
What is the size of Protozoa? |
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Definition
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Term
What is the purpose of encystation? |
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Definition
a. protection against unfavorable external environmental conditions b. nuclear division c. parasite transmission *d. all of the above |
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Term
Organisms in Protozoa are: |
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Definition
*c. single-celled, eukaryotic |
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Term
Protozoa can reproduce both sexually and asexually. |
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Definition
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Term
Native cells first encounter which of the following cell receptors: |
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Definition
b. IgM c. IgD *d. both b and c |
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Term
There are five different classes of antibodies distinguished by heavy chains called Isotypes. Which class is associated with hypersensitivity? |
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Definition
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Term
Antigen-presenting cells that activate helper T cells must express which of the following on their surfaces? |
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Definition
*C. Class II MHC antigens |
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Term
What is the portion of antigen that is bound by a given antibody or recognized by T cell defined as? |
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Definition
*b. Antigenic determinant |
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Term
Which Immunoglobulin comprises as much as 80% of all antibodies in the blood? |
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Definition
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Term
Globular proteins are produced by which immune cell type? |
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Definition
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Term
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Definition
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Term
During primary and secondary immune responses, the antibody or antibodies involved is/are: |
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Definition
a. IgM b. IgA c. IgG *d. Two of the above |
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Term
The response of IgG during a first exposure is exactly the same as it is during a second exposure. |
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Definition
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Term
The innate immune response is specific to a microbe. |
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Definition
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Term
All the following are true of the adaptive immune response except? |
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Definition
*b. The magnitude of the response decreases with every encounter |
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Term
Which of the following are associated with MHC class II? |
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Definition
a. binding of peptides from molecules that are internalized by cell b. CD4+ T cells |
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Term
The HIV virus targets which type of cell as a receptor? |
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Definition
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Term
A deficiency in this immunoglobulin isotype, the major isotype found in the intestinal tract, can lead to higher susceptibility to Giardia infection. Which isotype is it? |
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Definition
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Term
Which of the following is a similarity between phagocytosis and endocytosis? |
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Definition
*c. They are both part of the immune system. |
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Term
According to the clonal selection theory, B cells become committed to antibody formation.. |
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Definition
*b. In the absence of the antigen |
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Term
Antibodies are specific to their native conformations. |
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Definition
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Term
Immunological memory provides long-term immunity. |
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Definition
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Term
T cells bind to antigens in their native conformations. |
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Definition
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Term
Which Immunoglobulin can form a pentamer? |
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Definition
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Term
Each antibody has how many equivalent binding sites? |
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Definition
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Term
Regarding adaptive immune response, what increases with each encounter? |
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Definition
*E. Magnitude of response and Affinity only |
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Term
Which of the following statements is FALSE regarding B cells? |
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Definition
*d. B cells commitment to antibody specificity occurs after exposure to the antigen |
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Term
What is the most prevalent immunoglobulin isotype found in serum (blood)? |
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Definition
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Term
High levels of eosinophils are often indicative of worms. |
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Definition
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Term
Which of the following is NOT a characteristic of Adaptive Immune Response? |
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Definition
*c. It is not specific to microbe |
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Term
Most immune cells originate from stem cells found in bone marrow. |
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Definition
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Term
Which of the following cytokines is INCORRECTLY paired with its function? |
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Definition
*b. IL 10; stimulates B-cell differentiation |
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Term
In a humoral reaction, specialized molecules in the circulatory system interact with the parasite, forming immune complexes. |
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Definition
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Term
Insecticides are the most ecological way to control intermediate hosts. |
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Definition
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Term
Except certain viral infections, parasitic diseases are more difficult to control than other infectous diseases. |
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Definition
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Term
Parasites reproduce fast with a large number of progeny. |
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Definition
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Term
Caterpillars are invading a small garden. Certain plants in the garden set off a pheromone. Wasp migrate and kill the caterpillars. What type of interaction is this? |
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Definition
*b. Tritrophic interaction |
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Term
A hosts spleen and red blood cells have become enlarged because of a parasite. What type of effect does this parasite have on the host? |
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Definition
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Term
Constant cell damage, which causes death of cells or tissues, is an example of: |
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Definition
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Term
Each time our bodies encounter an antigen, there is refinement of the immune response so that next time, our bodies are better at recognizing the invading entity. This is an example of which of the following? |
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Definition
*a. increasing affinity within the adaptive immune response |
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Term
Th1 cells characteristically secrete interleukin 2, gamma interferon, and tumor necrosis factor (TNF) |
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Definition
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Term
T-cells are activated by which of the following? |
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Definition
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Term
The components of innate immunity in eukaryotic cells include: |
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Definition
a. secretions b. linings of internal tracts c. Phagocytic cells (macrophages, neutrophils. and natural killer cells. *d. all of the above |
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Term
Which of the following is NOT true of antibodies? |
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Definition
*c. Antibodies are produced by both B cells and T cells. |
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Term
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Definition
*d. Are unique in that they can only recognize antigens presented to them by another cell (usually a macrophage). |
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Term
Component proteins are part of cellular innate immunity. |
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Definition
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Term
What type of immune cells derived from myeloid progenitor cells is specialized for parasitic infection? |
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Definition
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Term
One important group of opsonin molecules is complement protein. |
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Definition
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Term
The main difference between B cells and T cells mentioned in lecture is that: |
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Definition
*c. Only B cells secrete their immunoglobulin receptors as plasma antibodies. |
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Term
Which of the following is not a type of membrane protein? |
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Definition
*b. cytoskeletal proteins |
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Term
The main difference between phagocytosis and endocytosis is: |
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Definition
*d. the participation of actin in phagocytosis |
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Term
Intermediate filaments is composed of: |
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Definition
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Term
A cell can respond to a signal by: |
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Definition
a. activating enzyme activity b. changing its cytoskeleton |
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Term
The inner and outer leaflets of the plasma membrane bilayer feature identical lipid profiles. |
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Definition
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Term
What are blood-borne factors that can coat particles to be ingested? |
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Definition
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Term
Drugs that limit or restrict worm mobility in the gastrointestinal tract MOST LIKELY involve which of the following cell feature that helps increase the effectiveness of the treatment? |
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Definition
*b. the worm's cytoskeleton |
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Term
Lipid-soluble molecules, such as alcohols, cannot diffuse through the plasma membrane. |
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Definition
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Term
[___________] proteins are covalently linked to membrane via a lipid molecule. |
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Definition
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Term
Which of the following describes the fluid-mosaic model of the plasma membrane? |
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Definition
*b. phospholipid bilayer with embedded proteins |
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Term
Which is NOT a part of the eukaryotic cell nucleus? |
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Definition
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Term
Which of the following is true about phagocytosis (e.g., the endocytic pathway of parasites)? |
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Definition
*b. Phagocytosis is dependent on microfilaments. |
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Term
Which of the following is incorrect? |
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Definition
a. Being diploid allows the parasites to combine its chromosome and generates diversity. b. The advantage of being diploid is different from the advantage of sexual reproduction in parasites. *c. All parasites known are diploid. d. DNA is packaged into chromosomes |
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Term
Which of the following is not involved in motility of the cell? |
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Definition
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Term
Which of the following is false regarding commensal microbes? |
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Definition
a. Antigenic and can elicit antibody responses b. Synthesize metabolites that are essential nutrients for the host c. Acquired by infection *d. All of the above are true |
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Term
Which characteristic is not true of the plasma membrane? |
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Definition
*b. It ensures compartmentalization within the cell. |
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Term
What parasite can survive the harsh conditions of lysosomes fusing to the phagosome in which it is contained and prevent the host from killing it? |
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Definition
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Term
What are the classes of phagocytic receptors? |
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Definition
*b. opsonin-dependent and non-opsonin dependent |
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Term
What are the classes of endosomes? |
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Definition
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Term
Phagocytosis is the process by which: |
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Definition
*c. specialized cells (macrophages, neutrophils, dendritic cells) internalize particulate material greater than 0.5um in diameter. |
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Term
All of the following are classifications of membrane proteins in a eukaryotic cell EXCEPT: |
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Definition
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Term
The [________] is the site where synthesized proteins and other materials are sorted, modified and from where they are transported to specific cellular destinations. |
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Definition
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Term
Which of the following membrane proteins include receptors? |
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Definition
a. Integral Proteins c. Lipid Anchored Proteins |
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Term
What are the functions of the cytoskeleton? |
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Definition
a. Provide movement of cilia and flagella b. Transport materials and organelles within the cell |
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Term
MHC class I and class II are present in all cells, making them antigen presenting cells. |
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Definition
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Term
The host-pathogen interaction always results in disease. |
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Definition
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Term
[________] Circular RNA with no protein coat |
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Definition
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Term
[________] Virus injects genetic information into host cell DNA and becomes a provirus |
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Definition
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Term
[________] Virus hijacks host cell machinery to replicate itself; kills host cell |
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Definition
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Term
[________] Is not a living cell |
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Definition
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Term
Which of the following proteins span the membrane? |
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Definition
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Term
The endoplasmic reticulum performs the following function(s)? |
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Definition
a. Protein synthesis b. Lipid synthesis |
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Term
Some cyanobacteria as well as plants are capable of performing photosynthesis. |
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Definition
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Term
The following can be found in both Prokaryotes and Eukaryotes except? |
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Definition
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Term
What is the significance of membranes to host-parasite relations? |
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Definition
*a. The parasite has to avoid activating the host via membrane proteins |
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