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ZOO 3115; Dr. Cherrington, Respiration (04-17)
Study material for UW ZOO 3115, Exam 3
22
Physiology
Undergraduate 3
05/05/2015

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Term
(04-17) when looking at the results of FEV/FVC, what is the range that is indicative of a disease?
Definition
>80%
Term
(04-17) The vitalograph for a person shows an FEV1 of 4 L and an FVC of 5 L. What would an asthmatic's look like?
Definition
The FEV1 would be lower (3 vs. 4 L and the FVC would still be 5 L, but it would take longer to reach. Why: Increased resistance and flow
Term
(04-17) What are the two main restrictive respiratory diseases?
Definition
Infant respiratory distress syndrome and asbestosis.
Term
(04-17) The vitalograph for a person shows an FEV1 of 4 L and an FVC of 5 L. How would asbestosis change it?
Definition
FEV1 would be the same (4 L), but FVC would have be reduced (4 L); Why: loss of lung capacity
Term
(04-17) What type of respiratory disease is emphysema?
Definition
Restrictive and obstructive
Term
(04-17) In the vitalograph for emphysema, what is changed from a normal person?
Definition
FVC and FEV1
Term
(04-17) Define minute ventilation (mv) and give its equation.
Definition
The volume of air moved each minute (respiratory rate)(tidal volume)
Term
(04-17) Define dead spage volume (DSV).
Definition
Inhaled air that does not take part in gas exchange
Term
(04-17) Define Alveolar ventilation (AV) and give its equation and units
Definition
The volume of air involved in gas exchange each minute. -- (respiratory rate)((tidal volume)-(dead space volume)) = mL/min
Term
(04-17) A student has a VT of 150 and an RR of 40. What is her MV? AV?
Definition
6000 mL/min; 0 mL/min !!!
Term
(04-17) What is the standard Patm at sea level?
Definition
760 mmHg or 1 atm
Term
(04-17) What are the three main components of the atmosphere?
Definition
Nitrogen, oxygen, carbon dioxide
Term
(04-17) What is Dalton's law?
Definition
The total pressure of a gas mixture is equal to the sum of the partial pressures of its components.
Term
(04-17) Using Dalton's law, how can you find the total pressure?
Definition
there is always 21% oxygen and 78% nitrogen in the air, and you should know the pressure at your altitude. With these partial pressures, we can add them to calculate the approximate total pressure.
Term
(04-17) Why doesn't alveolar PO2 equal 160 mmHg at sea level?
Definition
1) Dead space volume 2) Presence and pressure of water
Term
(04-17) What is the partial pressure of water at 37 degrees C?
Definition
Around 47 mmHg
Term
(04-17) What is Henry's law? What is the formula?
Definition
The concentration of gas dissolved in a liquid is proportional to its solubility and its partial pressure.; [x] = (Solubility coefficent that will be given) (Partial pressure of specified gas)
Term
(04-17) What are the units of the solubility coefficient?
Definition
mL per 100 mL per mmHg
Term
(04-17) At the same partial pressure, will gas concentrations in solution be equivalent?
Definition
Nope; it depends on the solubility coefficient and temperature
Term
(04-17) What is the main way you can get decompression sickness?
Definition
Scuba diving, you can be at a pressure of 2 atm. As the pressure increases, nitrogen's solubility increases. If you don't let them slowly come out of solution, the can come out rapidly, causing the nirogen to come out of solution in your bloodstream
Term
(04-17) What is the equation for finding how much oxygen is in blood?
Definition
[Oxygenblood] = [Oxygensolution (plasma)] + [Oxygenheomglobin] or [Oxygenblood] = (3 mL O2/L) + (191 mL/L)
Term
(04-17) What is the equation for [Oxygenhemoglobin]?
Definition
(carrying capacity of Hb)([Hb])(fractional saturation of Hb)
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