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Yersinia, Francisella, Brucella, and Pasteurella
chapter 11
8
Microbiology
Graduate
12/31/2009

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Term
What are the common characteristics of yersinia, francisella, brucella, and pasteurella?
Definition
* gram(-) rod
* zoonotic disease
* very virulent (not pasteurella)
* facultative intracellular organism (not pasteurella)
* treat with aminoglycoside (gentamicin or streptomycin) and/or doxycycline (not pasteurella)
Term
What causes bubonic plague?
Definition
Yersinia pestis
Term
What are the virulence factors of Yersinia pestis (resist destruction after phagocytosis)?
Definition
* Fraction 1: capsular antigen
* V antigen: protein
* W antigen: lipoprotein
Term
How is tularemia acquired?
Definition
by handling rabbits, bites of ticks and deerflies.
Term
Which organism causes tularemia?
Definition
Francisella tularensis
Term
Different presentations of tularemia
Definition
* ulceroglandular tularemia
* pneumonic tularemia
* oculoglandular tularemia
* typhoidal tularemia (GI tract)

tularemia is similar to bubonic plague, but with much lower mortality
Term
Contact with animal causes infection, no primary skin ulcer, undulant fever (slow rise in temperature during the day). Which organism?
Definition
Brucella
Term
Which organism causes the most frequent infection after cat/dog bite?
Definition
Pasteurella multocida. Treat with penicillin or doxycycline.
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