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Yale BENG 100 - Exam 1.3
Yale BENG 100 - Exam 1.3 (BME Saltzman)
21
Engineering
Undergraduate 1
03/02/2010

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Term
flow diagram of system
Definition
reproductive, renal, respiratory, digestive systems have outs, circulatory, nervous, endocrine, muskulaskeletal, and immune don't
Term
steps of communication
Definition
ligand, ligand + recepor, enzymes, 2nd messengers, enzymes, response!
Term
agonist/antagonist
Definition
agonist: mimics a ligand (insulin). antagonist: inhibits the action of a ligand (beta blockers)
Term
types of ligand receptors
Definition
ligand-gated ion channel, g-protein receptors (releases protein subunits), receptor tyrosine kinases (rtk, dimerize), receptors linked to enzymes
Term
phosporylation requires
Definition
ATP, leave OH group
Term
types of communication
Definition
cell-cell, autocrine (like t-cells, self stimulating), paracrine (chemical synapses, eg), endocrine (eg hormones)
Term
protein horomone/steroid hormone diffs
Definition
protein: hydrophilic, binds to surface receptors
steroids: hydrophobic, bind to intracellular receptors
Term
how the synapse balance works
Definition
[K] larger in than out, [Na] larger out than in, opening [K] channels makes a gradient force, but the voltage force plays too!
Term
parts of neuron
Definition
dendrites, axon, soma, axon terminals, myelin sheaths, nodes of ranvier
Term
draw the action potential mechanism voltage diagram
Definition
[image]
Term
immunology
Definition
study of host protection from foreign macromolecules or invading response to them
Term
four classes of pathogens?
Definition
bacteria, viruses, fungi, and parasites
Term
immune responses
Definition
innate (for extracellular) or adaptive (humoral or cell mediated, for vesicular or cytosolic antigens)
Term
how an infected cell is destroyed
Definition
MHC-I shows protein part that is recognized by T-cytotoxic cell, that activates other T-c cells to kill 'em.
OR
phagocytosis and presentation by mhc-II and recognized by Thelper which activate other Thelper to get B cells producing antibodies or gets macrophages
Term
B cells do what??
Definition
make antibodies!
Term
vaccine
Definition
a preparation of all or part of an infectious agent that primes the immune system to recognize it, without causing it
Term
small pox vaccine
Definition
jenner made vaccine from cowpox lesions in dairymaids (probs - arm-to-arm method, and length of protection)
Term
biotech of smallpox vaccine
Definition
naturally occuring, attenuated vaccine. 1940s showed large scale production of freeze dried vaccine
Term
antibody responses
Definition
secondary much quicker and stronger than primary
Term
salk does what
Definition
prepares killed vaccine for polio (later someone develops oral)
Term
types of vaccines
Definition
natural, attenuated live vaccine (smallpox)
killed virus (salk polio)
lab attenuated virus (sabin polio)
purificiation of subunit (hep. b)
rcombinant dna to produce subunit (now hep b)
dna vaccine (investigational)
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