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WSU Pathophysiology Unit 8 -STD's
N/A
22
Pathology
Undergraduate 2
04/15/2012

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Term
What is Treponema pallidum?
Definition
A gram negative helical bacterium (spirochete) that lives in a host and is responsible for Syphilis.
Term
Syphilis- primary infection
Definition
Sexual transmission occurs through broken skin or mucus membranes coming in contact with an open lesion.
Term
Syphilis- secondary infection 
Definition
Characterized by systemic spread of syphilis (dissemination) across the organism.
Term
Syphilis- tertiary stage
Definition
Characterized with: large skin lesions (gummas), degeneration of spinal cord (neurosyphilis), destruction of elastic aorta tissue and can mimic meningitis.
Term
What STD can occur starting at 18 weeks gestation. Has a perinatal death rate of up to 40%?
Definition
Syphilis- Congenital Infections
Term
What test detects the precence of Rapid Plasma Reagin (RPR)?
Definition
Treponemal serological test which is used to diagnose Syphilis.
Term
Chlamydia trachomatis is...?
Definition
A obligate intracellular gram negative coccus bacterium.
Term
What is the most common STI and how many new cases are diagnosed each year in the U.S.?
Definition
Chlamydia and 3 million per year.
Term
What is Reiter syndrome?
Definition
A systemic infection of chlamydia with common inflammations such as urethritis, arthritis, conjunctivitis and mucocutaneous lesions.
Term
Herpes simplex I & II remain dormant where and how long?
Definition
In the posterior root ganglion or trigeminal ganglion and my stay dormant for an entire lifetime.
Term
How many new cases of herpes are diagnosed each year?
Definition
1 million
Term
Herpes symptoms incude...?
Definition
Painful blister-like lesions on external genitalia.
Term
Acyclovir (Zovirax or Valtrex) is used to treat what STD?
Definition
Herpes simplex I & II
Term
Herpes Simplex include complications include?
Definition
Spontaneous abortions and neonatal morbidity due to CNS infection.
Term
Condylomata Acuminata is another name for..?
Definition
HPV or Human Papilloma Virus
Term
HPV appears several weeks to several months after contact and can cause which types of cancer?
Definition
It can cause Cervical, Anorectal and Penile cancers.
Term
Which HPV strands cause 70% of all cervical. Cancers?
Definition
HPV-16 and HPV-18
Term
Gardisil and Cervarix vaccinate against what STD?
Definition

HPV- 16 and -18 (cervical cancer strands).

HPV-6 and -11 (genital wart strands)

Term
What is Trichomonas vaginalis?
Definition
A sexually transmitted protozoan parasite.
Term
What are some symptoms of Trichomoniasis?
Definition
Erythema of vaginal wall, yellow-green discharge, pruritis, painful intercourse and dysuria.
Term
What is Sarcoptes scabiei?
Definition
A human itch mite that burrows into upper layer of skin and lays eggs which causes intense itching and pimply rash.
Term
What is Pediculosus Pubis?
Definition
Aka "crabs" or Phthirus pubis that causes pruritus.
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