Term
| Why is the brain different? |
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Definition
FCCOGSSCPP
Functional localization, Complex, Cells, Oxygen and glucose deprivation sensitivity, Swelling: cytotoxic and vasogenic, Swelling causing herniation syndromes, CSF, Plastic, Psychiatry and neurology |
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Term
| Missing amygdala can lead to what? |
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Definition
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Term
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Definition
| Loss of facial recognition |
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Term
| Main focus of homunculus? |
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Definition
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Term
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Definition
| 100 billion nuerons, with 50k synaptic connections each, 2 trillion glial cells, active glial cells that control the micro-environment |
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Term
| Oligodendroglia: origin? HE? purpose? |
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Definition
-Ectodermal.
-only nuclei visible with HE
-provide and maintain myelin sheath for multiple CNS axons |
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Term
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Definition
Neurons
Glia: Astrocytes, oligodendroglia, ependymal cells
Microglia |
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Term
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Definition
1. Some neurons lack dendrites
2. dendrites increase # of ribosomes
3. More arborization = more input
4. Data integrated at axon origen |
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Term
| Neurons: Origen? HE? Shape? |
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Definition
-ectodermal origin
-For cortical neurons: Nissel bodies (RER), prominent nucleus, prominent nucleolus, HE not good for seeing dendrites
-Shape and size vary with location, NT profile |
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Term
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Definition
Not reversible
-5-7 minutes sans O2 neurons die
-Perikaryal cytoplasm becomes pink and homogenous
-nucleus is dark and shrunken
-4 to 6 hours after injury becomes visible microscopically |
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Term
| Brain regions sensitive to anoxic (neuronal) damage |
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Definition
-cortical laminar necrosis (cortical layers 3 and 5)
-Hippocampus (CA1 region, Sommer's sector)
-Purkinje cells of cerebellum |
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Term
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Definition
From hypoxia, ischemia, or hypoglycemia.
-irreversible damage
-shrink, eosinophilic from mito condensation
-nuclei become pyknotic |
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Term
| Axonal Reaction, if axon is transected |
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Definition
-secondary nerve cell charge
-reversible if integrity of axon restored
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