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WHS Protein Synthesis and Mutation
Protein Synthesis, Mutations
61
Biology
10th Grade
10/16/2009

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Term
Function of DNA:
Definition
Holds the code of genetic info. for building proteins.
Term
What are examples of Proteins in the body? (3 things)
Definition
*Enzymes
*Hormones structures *Nummerous tissues and structures
Term
Why are DNA's "instructions" TRANSCRIBED to the m-RNA molecule?
Definition
Because DNA cannot leave the nucleus.
Term
What does m-RNA do with the instructions from the DNA?
Definition
Carries the instructions to the Ribosomes in the Cytoplasm where proteins are made.
Term
What does mRNA stand for?
Definition
Messenger Ribonucleic Acid
Term
How is RNA different from DNA?
Definition
1. sugar is Ribose (NOT deoxyribose like DNA)
2. Single strand
3. Uracil replaces thymine as a base pair
Term
In mRNA, what replaces thymine in the base pairing rules?
Definition
Uracil
Term
What opens the DNA strand for trascription?
Definition
RNA polymerase
Term
What is the first step of Transcription? (out of 5 steps)
Definition
DNA unzips
Term
What is the second step of Transcription? (out of 5 steps)
Definition
mRNA makes complementary strand
Term
What is the third step of Transcription? (out of 5 steps)
Definition
DNA zips back up
Term
What is the fourth step of Transcription? (out of 5 steps)
Definition
mRNA message is processed: introns (non-coding regions) are removed
Term
What is the fifth step of Transcription? (out of 5 steps)
Definition
mRNA leaves the nucleus and goes out to ribosome in the cytoplasm
Term
What is a Codon?
Definition
Nucleotide triplet in mRNA that codes for a particular amino acid.
Term
What determines the structure and funtion of a protein?
Definition
The order and the sequence of the bases in the gene.
Term
What determines which amino acid will be added to a growing protein chain?
Definition
The order of the codons in mRNA.
Term
What is the first step in Translation? (out of 5 steps)
Definition
mRNA takes message to ribosome in cytoplasm
Term
What is the second step in Translation? (out of 5 steps)
Definition
tRNA picks up Amino acids in cytoplasm and carries them to ribosome.
Term
What is the third step of Translation? (out of 5 steps)
Definition
tRNA anticodon binds to mRNA codon
Term
What is the fourth step of Translation? (out of 5 steps)
Definition
The amino acid detaches from tRNA and attaches to growing protein.
Term
What is the fifth step of Translation? (out of 5 steps)
Definition
A different tRNA brings a second amino acid and drops it off (this continues until all of the amino acids of the protein are dropped off)
Term
How many amino acids are there?
Definition
20
Term
The genetic code is _______ in all organisms.
Definition
Universal
Term
What is a Mutation?
Definition
Any change in a cell's DNA
Term
Where can mutations occur?
Definition
On a single gene or section of a chromosome, or the entire chromosome.
Term
What causes mutations?
Definition
Can be caused by Mutagens,Carcinogens, and can be natural/random
Term
What is a Mutagen?
Definition
A physical or chemical cause of mutation. (UV light, radiation, drugs, toxins...)
Term
What is a Carcinogen?
Definition
Anything that causes cancer
Term
Are mutations always bad? Give an example.
Definition
No, new proteins might be advantageous and lead to evolution
Term
What is a Karyotype?
Definition
Picture or display of your chromosomes
Term
What are some examples of Non-disjunction?
Definition
*Chromatids fail to separate in meiosis II
*Trisomy
*Monosomy
Term
What is a Point Mutation?
Definition
*single nucleotide is altered. Can change 1 amino acid in protein.
Term
What is this an example of?
**** ggacAatca ***ggacCatca
Definition
Point Mutation
Term
If mRNA is GGC, what's the DNA?
Definition
CCG
Term
What is a Frameshift Mutation?
Definition
A nucleotide is either inserted or deleted from a gene
(ALL of the triplets from the point of mutaion onward will be changed)
Term
What is Frameshift Mutation Insertion?
Definition
When a nucleotide is added or deleted from a gene and the reading frame shifts over one base.
Term
What is thin an example of?
*** the fat cat ate the rat
*** the fAa tca tat eth era t
Definition
Frameshift Mutation INSERTION
Term
What is Frameshift Mutation Deletion?
Definition
A deletion occurs when a nucleotide is removed from a gene
Term
What is this an example of?
**** thE fat cat ate the rat
**** thf atc ata tet her at
Definition
Frameshift Mutation DELETION
Term
What is the result of Deletion?
Definition
A portion of a chromosome is lost.
Term
What is Inversion?
Definition
A segment of a chromosome will reverse end to end.
Term
Duplication
Definition
A segment of a chromosome is duplicated producing extra copies of genes- on a chromosome
Term
Translocation
Definition
A part of a chromosome joins another non-homologous chromosome
Term
[image]
Definition
Deletion
Term
[image]
Definition
Point Mutation
Term
[image]
Definition
Translocation
Term
[image]
Definition
Inversion
Term
[image]
Definition
Deletion
Term
[image]
Definition
Inversion
Term
[image]
Definition
Duplication
Term
[image]
Definition
Translocation
Term
What type of Mutation?
*aat gcc agt ggt tcg
*aat gcc agt gCg ttc g
Definition
Insertion C Frameshift
Term
What type of mutation?
* aat gcc agt ggt tcg
* atg cca gtg gtt cg
Definition
Deleted an A Frameshift
Term
what type of mutation?
* tag tag aaa cca caa agg ata
* tag Cta gaa acc aca aag gat a
Definition
Insertion Frameshift
Term
What type of mutation?
* tag tag aaa cca caa agg ata
* tag tag aTa cca caa agg ata
Definition
point mutation substitution
Term
What type of mutation?
* aat gcc agt ggt tcg
* aat gcc gct tgg tga
*
Definition
Inversion tail end flips back over
Term
What is translocation?
Definition
Gene jumping--a segment of one chromosome jumps to another chromosome.
Term
Which type of mutation can cause enormous genetic changes and rapid evolutionary advances?
Definition
Translocation
Term
True or False?
***All organisms share the same genetic bases.***
Definition
True.
Term
If tRNA is AAU, what's the mRNA?
Definition
UUA
Term
You need to know the ______ to use the chart to determine the amino acids.
Definition
mRNA codons
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