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White Blood Cells
68K 12-01 Hemo 101 Unit 2
24
Other
Undergraduate 2
01/12/2012

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Term
Mature Eosinophil
Definition
10-16 microns, generally round, cytoplasm colorless with large distinct granules that stain red-orange (distinguishing feature), eccentric nucleus, usually bilobed.
Term
Mature Basophil
Definition
12-17 microns, generally round, 2-4lobed nucleus, deep blue-purple, slightly pink to clorless cytoplasm, large coarse granules stain deep purple(distinguishing characteristic) may obscure nucleus, water-soluble.
Term
Segmented Neutrophil
Definition
9-15 microns, N/C 1:1, Pale, lilac with blue shades and fine dust like granules in cytoplasm, 2-5 purplish red lobes on nucleausdense coarse clumped irregular chromatin.
Term
Basophil Myelocyte
Definition
Large, dark blue-purple granules.
Term
Eosinophil Myelocyte
Definition
Round and large, dirty-orange to blue granules.
Term
Neutrophilic Myelocyte
Definition
Very fine and pinkish in color, granules that usually begin near the nucleaus.
Term
Eosinophil Granules
Definition
contain histaminase and are highly refractive.
Term
Neutrophil Functions
Definition
seek, injest and kill bacteria, most numerous granulocyte, circulate for approximately 10 hours, Infants and children have fewer than adults, Phagocytes.
Term
Eosinophil Function
Definition
react to allergic reactions and certain parasitic infections, granules contain histaminase and are highly refractive. (distinguishing feature)
Term
Basophil functions
Definition
Involved in hypersensitivity reactions, granules release histamines in hypersensitivity reactions. Contain heparin.
Term
Neutrophilic Band
Definition
10-16 microns, N/C 1:1 Moderate to abundant pink cytomplast with blue-pink granules. Nucleus is band or rod shape, deeply indented.
Term
Metamyelocyte
Definition
domination of increasing secondary granules. Nucleus is kidney bean shaped. 10-18 microns, moderate to abundant cytomplasm with secondary granules, Indention less than 1/2 the width of the nucleus.
Term
Myelocyte
Definition
cell ceases to produce primary granules 12-18 microns N/C 2:1-1:1, cytoplasm may contain a few patches of blue, granules are small, specific, very fine and pinkish in color, Nucleus is round, central, no nucleoli.
Term
Monoblast
Definition
12-20um, n/c ratio 4:1, cytoplasm is moderately basophilic to blue-gray, non granular, round or oval nucleus fine, lacy, light blue to purple, 1-2 nucleoli, eccentric.
Term
Promonocyte
Definition
12-20microns N/C ratio: 3:1-2:1, blue gray cytoplasm moderate amount, dust like azurphilic granules, nucleaus oval may have single fold, 1-5 nucleoli.
Term
Monocyte
Definition
Still cpapble of cell division, largest of all WBCs, 12-18 microns N/C 2:1 to 1:1, abundant abounts of gray to gray-blue cytoplasm, fine granules give a "ground glass appearane, vacoules present. Nucleus is large and be round, indented, lobular, or horseshoe.
Term
Monocyte Life Span
Definition
enters blood for 2-3 days, then entere tissues where the turn into histocytes and macrophages, histocyte first lay in tissues for months, inactive, until the eat bacteria then macrophage.
Term
Lymphocyte characteristics
Definition
2nd most numerous WBC, originate from lymphoid stem cell line, produced primarily in the thymus and marrow, secondaryily spleen, peyer's patches waldeyer ring, lymph nodes and lympoid organs.
Term
Lymphocyte Maturation
Definition
Lymphoblast, prolymphocyte, lymphocyte, small and large mature lymphocytes.
Term
Lymphoblast
Definition
15-20Microns, N/c 4:1, scanty amount of cytoplasm, no granules stains moderate to dark blue, round or oval nucleaus, smooth chromatin, red purple color, 1-2 distinct nucleoli.
Term
Pro-lymphocyte
Definition
15-18 mcirons, 4:1 - 3:1 N/c scanty amount of moderate dark blue cytoplasm, may have a few graules, round, red purple mnucleus condensed lue chromatin, 1-2 nucleoli.
Term
Small Lymphocyte
Definition
6-9 microns, 4:1 N/C, small rim cytoplasm, usually absent of granules, oval nucleus with carse lumpy chromatin, no nucleoli
Term
Large lymphocyte
Definition
15-18 microns, 2:1 N/C, stains lighter than small lymphocytes, No nucleoli
Term
Lymphocyte function
Definition
serve to direct the immune response system in the body, responsible for the recognition of foreing antigens an function in antibody production.
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