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VTT244 Pharmacology
Pain and Inflammation
42
Veterinary Medicine
Not Applicable
09/22/2013

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Cards

Term
Pain Pathway
Definition
Transduction
Transmission
Modulation
Perception
Term
Transduction
Definition
Site at witch a painful stimulus occurs and is converted inot an electrical signal that will go to the CNS throught afferent nervers
Term
Transmission
Definition
involves peripheral nervers that send the noxious stimulus to the doral horn of the SC, through the SC, and finally to the brain
Term
Modulation
Definition
Alters the noxious stimulus
Term
Perception
Definition
The brain deciphers the information that it has received and interprets the information as pain
Term
2 types of pain
Definition
Somatic pain
Visceral pain
Term
Somatic Pain
Definition
Pain of skin, SQ, muscle, bones, and joins.
Term
Visceral Pain
Definition
Pain of the visceral organs
Term
Mild to moderate pain
Definition
OVH
Castration
Dental procedures
Term
Moderate pain
Definition
Laparotomy
Cystotmy
Gastrotomy
Mass romoval
Term
Moderate to severe Pain
Definition
Fracture repair
joint surgery
mammary gland surgery
enucleation
ear surgery
Term
Severe to excurciating pain
Definition
neuropathic
multiple fractues
bone cancer
Term
Hyperesthesia
Definition
Refers to an increase in sensitivity to stimuli like sounds and touch
Term
neuropathic pain
Definition
pain due to damage of peripheral nerve or the SC itself, this type of pain is often poorly responsive to meds
Term
Inflammation basic
Definition
redness
heat
swelling
pain
Term
Cyclooxygenase
Definition
is one of the enzymes in the inflammatory cascade
Term
cyclooxygenase is responsible
Definition
for making prostaglandins
Term
cox-1
Definition
mantains physiologic function like renal blood flow and the synthesis of the gastic mucosa(good prostaglandins)
Term
cox-2
Definition
Stimulates formation of the prostaglandins witch mediate inflammation and pain(bad prostaglandins)
Term
Pyrogen
Definition
is a substance witch can induce fever
Term
exogenous pyrogens
Definition
come from outside the body, such as viruses and bacteria
Term
endogenous pyrogens
Definition
come from inside the body and are usually chemical mediators such as prostaglandis
Term
NSAID
Definition
Non-steroidal Anti-inflammatory drugs
Term
NSAID adverse effects
Definition
-GI ulceration and bleeding as they interfere with the normal mucus coating
-hepatotoxicity
-nephrotoxicity
Term
NSAID are
Definition
-asprin
-phenylbutazone
-flunxin meglumine
-surpass
-carprofen
-ketoprofen
-meloxicam
-deramaxx
-tepoxalin
-fircoxib
-acetaminophen,ibuprofen
Term
acetylsalicylic uses
Definition
analgesic, anti-inflammatory anti-pyrexia, and anti-platetlet effect
Term
Phenylbutazone
Definition
mostly in horses, used for analgesic and anti-pyrtic and anti-inflammatory properties
Term
Bute
Definition
-mild to moderate pain
-fever reducer
-anti-imflammatory
Term
Flunixin Meglumine uses
Definition
analgesic,anti-inflammatory, anti-pyrexia
Term
Surpass use
Definition
in the treatment of osteoarthritis of hock, carpus, fetlock, and pastern joints in the horse
Term
Carprofen (rimadyl) use
Definition
anti-inflammatory and analgesic
Term
Ketoprofen uses
Definition
analgesic, anti-inflammatory, and anti-pyretic
Term
Ketoprofen use for
Definition
musculoskeletal pain and inflammation in horses and for post operative pain in dogs and cats
Term
Meloxicam uses
Definition
Analgesia, inflammation associated with osteoarthrits as well as for post-op pain
Term
Deracoxib (deramaxx)
Definition
Deramaxx is indicated for the treatmen for post-op pain and for the pain and inflammation associated with osteoarthrites in dogs
Term
Tepoxlin
Definition
dual inhibitor of both cyclooxygenase and lipooxygenase so it blocks both arms of the arachidonic acis cascade
Term
Firoixib (previcox)uses
Definition
treat pain and inflammation associated with canine and equine osteoarthritis
Term
DMSO
Definition
dimathyl sulfoxide
Term
DMSO IS
Definition
free radical scavenger that has anti-inflammatory and analgesic effects
Term
Glucocoricids AKA
Definition
Corticosteroids steriods
Term
Proparacaine
Definition
Rapid acting topical anesthetic used for ophthalmic procedures like tonometry
Term
Lidocaine
Definition
3/4 of the administered does reaches the general circulation
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