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VTT244 Pharmacology
Gastrointestinal Medications
24
Veterinary Medicine
Not Applicable
09/23/2013

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Cards

Term
Prostaglandins good are
Definition
Pge and Pgl
Term
Histamnie receptors
Definition
H2, located in the parietal cells, HCI
Term
Acetylcholine is in
Definition
the parasympathetic system
Term
Gastrin released
Definition
from the stomach wall in response gadtric distention-
-protein in the stomach
-stimulation by parasympathetic system
Term
CRTZ means
Definition
Chemorecepotor trigger zone
Term
CRTZ means
Definition
Chemorecepotor trigger zone
Term
CRTZ receptors designed to
Definition
detect toxins in the bllod and CSF
Term
Apomorphine
Definition
is an opiod so it must stimilat the CRTZ before the emetic center
-driectly stimulates dopamine receptors
Term
Xylazine
Definition
Stimulates the alpha receptors in CRTZ and emetic center in cats
-50-50 in dogs
Term
H2O2
Definition
works inconsistently
-can result in gastriris
Term
Antiemetic drugs
Definition
-cerenia
-metoclopramide
-centrine
-ondansetron(zofran)
Term
Cerenia
Definition
approved in use in dogs 8 weeks and 16 weeks in cats.
-
Term
cerenia acts
Definition
centrally by inhibiting Substance P, the key nurotrasmitter involved in vomiting.
Term
Metoclopramide acts
Definition
centrally anti-emetic as it antagonizes dopamine receptors in the CRTZ
Term
Centrine
Definition
Anticholinergic. antipasmodic
Term
ondansetron
Definition
5-ht3 receptor
-for severe vomiting when concevential antiemetic are ineffctive
Term
Anticholinergics
Definition
block the parasympathetic effect and allow the sympathetic effect to dominate resulting in decreased motility
Term
Opioidss
Definition
increase segmental contractions which deceasese gut motility and slows the transit time of intestinal contents
Term
Hypersecretion blockers
Definition
stimulation of mucosal cells of the GI tract results in secretion of ions that osmotically pull water to them, thus incrasing the water content of intestinal contents
Term
antacids uses
Definition
to decrease the acidity on the stomach or rumen
Term
Systemic antacids require
Definition
absorptione. circulation, and attachment to receptors on the stomach cells in order to work
Term
h2 blockers drugs
Definition
cimetidine (tagamet)
ranitidine (zantac)
Famotidine (pepcid)
Term
Prebiotics
Definition
tarfet the microbes already present in the GI trast acting as food for the microbes with beneficial cobsequences to the animal
Term
probiotics
Definition
contain good bacteria the help improve the digestibility of ingredients
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