Term
|
Definition
This drug is similar to phenobarbital structurally. given PO, and can induce liver enzymes that raise its own & other drug metabolism. |
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Term
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Definition
C-IV controlled subatsnace used for status epilepticus (IV) and then followeed by PO therapy. Increases GABA |
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Term
|
Definition
C-IV controlled substance. Used orally for adjunct anticonvulsant therapy & behavior phobias. Side effects include sedation and ataxia. |
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Term
|
Definition
Used as adjunct anticonvulsant therapy. Takes several days to reach therapeutic state. Loading dose then maintenece dose required. Side effects include elctrolyte imbalences. |
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Term
|
Definition
Oral anticonvulsant that increases blood levels of GABA. Limited use in vet med due to side effects. Blood work is necessary on this drug. |
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Term
|
Definition
Rarely used in vet med due to side effects. Anticonvulsants effects only noted after accumulation of doses. |
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Term
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Definition
Calms animals; used to reduce anxiety and aggression. |
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Term
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Definition
Decreases irratability & excitment, may provide analgesic effects. |
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Term
|
Definition
Lesson anxiousness but does not make the animal drowsy. |
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Term
Phenothiazine derivatives |
|
Definition
These drugs block dopamine & alpha-1 receptors found in smooth muscle of peripheral blood vessels. They cause sedation and relieve fear. They do not cause analgesia. Commonly used prior to minor procedures or as pre-anesthetic agents. |
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Term
Phenothiazine derivatives |
|
Definition
These types of drugs can cause paraphimosis (penile prolapse in horses). |
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Term
|
Definition
These anti-anxiety drugs are C-IV controlled substances. They produce muscle relaxation and have some anti-convulsant activity. Sometimes used as appetite stimulants in cats. They do not provide analgesia. An example of this drug class is Diazepam. |
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Term
|
Definition
Reversal agaent for benzodiazepines |
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Term
|
Definition
This drug class binds to alpha-2 receptors on neurons to prevent release of norepinephrine. They produce calming effects, some analgesia, and muscle relaxation. They decrease ability to respond to stimuli. An example is: Xylazine. |
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Term
|
Definition
This drug can be combined with ketamine for short term procedures in horses and cats. It produces analgesia in horses but vomitting in cats. It can slow insulin secretion which causes transient hyperglycemia. |
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Term
|
Definition
What is the reversal agenet for Xylazine (Rompun)? |
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Term
|
Definition
This drug produces better analgesia in horses. Labaled for sedation in horses, but horses can still respond to stimuli. |
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Term
|
Definition
Labled for sedation and analgesia in dogs over 12 weeks old. Used for minor surgical procedures and restraint. It initialy causes BP to rise and HR to lower. The IV and IM doses are different! |
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Term
|
Definition
Reversal agent for Medetomadine (Domitor) |
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Term
|
Definition
Opioid or opioid like substances that require a prescription. They work on the CNS. Used for moderate-severe pain in smooth muscle, organs, & bones. |
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Term
|
Definition
Less potent then narcotics, not addictive, and work on the PNS receptor sites. |
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Term
|
Definition
Naturally obtained from the poppy plant. They produce analgesia and sedation, & relieve anxiety. They produce their action on opioid receptors located in nervous tissues. Cats and horses are very sensitive to them. |
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Term
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Definition
Found in pain areas of the brain. Cause analgesia, euphoria, respiratory depression, & physical dependence. |
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Term
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Definition
Found in cerebral cortex and spinal cord. Produce analgesia, sedation & miosis (constriction of pupils) |
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Term
|
Definition
Found in the brain, this opioid receptor controls whinning, hallucinations, and struggling effects. May cause mydriasis (dilation of pupils) |
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Term
|
Definition
What are the 3 opioid receptors? |
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Term
|
Definition
This drug can be used as an anti-diarrheal in calves. C-II controlled substance. |
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Term
|
Definition
C-II controlled substance that is a Mu agonist. Used for severe pain. Pre-anesthetic & anesthetic. |
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Term
|
Definition
C-II controlled substance that is a Mu agonist with a short duration of action. Used for acute pain. Extra-label use in animals. Pre-anesthetic. |
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Term
|
Definition
A C-II controlled substance that is a semi-synthetic opioid that is 5x more potent then morphine. Mu agonist. it is used post op to produce sedation & offset moderate-severe pain. Duration of action is 4 hours.
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Term
Butorphanol (Torbugesic) (Torbutrol) |
|
Definition
C-IV controlled substance, synthetic opioid with kappa and mu receptor activity. It is not a very strong analgesic. Short duration of action. Can be used as a analgesic, pre-anasthetic, & antitussive. |
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Term
Hydrocodone (Tussigon) (Hycodan) |
|
Definition
C-III controlled substance, synthetic opioid, used as an antitussive. When combined with acetaminophen it makes Vicodin for use in humans. |
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Term
|
Definition
C-II controlled substance that is a sunthetic opioid 200x more potent than morphine. Used as an analgesic/ tranquilizer & chemical restraint. Available as a transdermal patch. |
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Term
|
Definition
C-III controlled substance that provides long term analgesia (8-10 hours) Used post-op. Side effects are rae but include respiratory depression. |
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Term
|
Definition
C-III controlled substance that is a synthetic opioid used as an antitussive in dogs. It can be combined with acetaminophen for pain relief in humans. |
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Term
|
Definition
C-V controlled substance that is a synthetic opioid. When combined with atropine it makes an antidiarrheal. |
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Term
|
Definition
Known as narcotic antagonists, they block the binding of opioids to their receptors. Used to treat respiratory and CNS depression caused by opioid use. Given IV for rapid onset of action. Examples include Naloxone & Naltrexone |
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Term
|
Definition
This drug is given IV or IM and has a high affinity for mu receptors. It reverses Meperidine, morphine, & oxymorphone. |
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Term
Neuroleptanalgesics
Ex: Xylazine--> butorphanol
Acepromazine--> morphine |
|
Definition
This class of drugs are a combination of an opioid & a tranquilizer or sedative. They cause CNS depression and analgesia. Opioid anatgainists can reverse their opioid effects. Veterinarians tend to make their own. |
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Term
|
Definition
This local anesthetic is for topical use and injection. |
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Term
|
Definition
This local anesthetic is for opthalmic use. |
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Term
|
Definition
This local anesthetic is used topicaly applied to skin and can also be opthlamic or otic solution. |
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Term
|
Definition
This local anesthetic has a longer onset and is used in epidurals and as oral nerve blocks. |
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Term
|
Definition
CNS depressants used as anti-convulsants, anesthetics, & euthenasia solutions. Can be long or short acting. Can cause cardiovascular & respiratiry depression. Highly irritating to perivascular tissue. |
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Term
|
Definition
C-III controlled substance that is an ultra short acting thiobarbiturate. Lasts 5-30 minutes. Has to be reconstituted. Caution in sighthounds. |
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Term
|
Definition
C-III controlled substance that is an oxybarbiturate similar to ultra short acting thiobarbiturate. Used in sight hounds. |
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Term
|
Definition
This class of drugs cause muscle rigidity, amnesia, and mild analgesia. Used only for restraint, diagnostic procedures and minor surgeries. Can cause minor cardiac stimulation, respiratory depression and exaggerated reflexes. |
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Term
|
Definition
C-III controlled substance approved for use in primates and cats. Need to use an eye lubricant when in use. Usually used in combination with drugs like ace, xylazine, and/ or diazepam. |
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Term
|
Definition
A responce mechanism that serves to maintain a state of internal constancy. Most common form of regulation in endocrine system. |
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Term
|
Definition
A responce mechanism that results in the amplification of an initial change. Results in avalanche-like effects. |
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Term
|
Definition
These hormones regulate growth & proper functioning of thyroid, gonads, & various endocrine glands. |
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Term
|
Definition
Blood glucose is regulated in a naqrrow range by; |
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Term
|
Definition
Responds to a rise in BG levels by using glucose for energy in cells and storage of glucose in liver as glucagon. |
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Term
|
Definition
Increases BG levels by promoting the breakdown of liver glycogen into glucose. |
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Term
|
Definition
Carb, protein, & fat metabolism caused by lack of or insufficient use of insulin in animals. |
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Term
|
Definition
Raised blood glucose, glucouria, PU/ PD, and weight loss are signs of: |
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Term
|
Definition
Used to initialy treat DKA & control BG until animal is stabalized. Duration of action is about 1/2 hr to 2 hr. |
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|
Term
Intermediate-acting insulin |
|
Definition
Used to control BG in uncomplicated cases of Diabetes Mellitus. Duration of action in dogs is 6-24 hrs and cats, 4-10 hr. |
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Term
|
Definition
Poorly absorbed from the tissue, therefore it maintains a long-lasting BG level. Duration of action in dogs is 6-28hr, and cats, 6-24 hr.
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Term
|
Definition
Animals growth & reproduction are regulated by hormones produced in the: |
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Term
|
Definition
Affect many metabolic, growth, reproductive, & immune functions. Help regulate fat & carbohydrate metabolism. Help regulate heat production. |
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Term
|
Definition
Dull coat, symmetrical hair loss, weight gain w/o increase in appetite, listlessness, intolerance to cold, reproductive failure, and skin more susceptable to dermatitis and pyoderma etc are signs of: |
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Term
|
Definition
This disease is diagnosed through blood work, measuring T4, T3, & TSH. |
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Term
|
Definition
Usually seen in cats, signs of this disease include PU/PD, weight loss, voracious appetite, tachycardia,vocalization, and restlessness. |
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Term
|
Definition
This is the principle mineralcorticoid which acts to conserve Na+ ions &H20. |
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Term
|
Definition
This disease is caused by too little hormones produced. Progressive condition associated with adrenal atrophy usually caused by immune mediated inflammation. |
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Term
|
Definition
This disease is caused by adrenal tumors, pituitary tumors, or long-term administration of corticosteroids. |
|
|
Term
Proestrus-->Estrus--> Metestrus--> Diestrus--> Anestrus |
|
Definition
Name the Estrous cycle in order of what happens. |
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Term
|
Definition
When graafian follicle present with estrogen, the predominent hormone. |
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Term
|
Definition
Where ova are produced in the ovary. |
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Term
|
Definition
When corpus luteum is present with progesterone the predominent hormone. |
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|
Term
GnRH
(gonadatropin-releasing hormone) |
|
Definition
The hypothalmus releases this in responce to stimuli such as daylight length & feedback mechanisms. |
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|
Term
FSH
(follicle stimulating hormone) |
|
Definition
This causes growth & maturation of ovarian follicles. |
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Term
|
Definition
This causes ovulation of mature follicles & formation of corpus luteum. |
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Term
|
Definition
This breaks down the CL at the end of pregnancy & at the end of diestrus in non-pregnant animals. |
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Term
|
Definition
Male sex hormones produced in testes, ovaries, & adrenal cortex. |
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Term
|
Definition
This hormone is used in vet medicine to treat infertility & hypogonadism. It is a C-III controlled substance. |
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Term
|
Definition
Side effects of using this hormone include; perianal tumors, prostatic disorders, & behavior changes. |
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|
Term
Zinc gluconate neutralized by arginine. (Neutersol) |
|
Definition
This is used as an injecctable chemicle sterilant that is injected into the testicles of 3-10mo old male dogs. It causes atropy of the tetsicles. |
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Term
|
Definition
This hormone is produced by the ovaries, testicles, adrenal cortex, & placenta. Promotes female sex characteristics, stimulates and maintains reproductive tract, and is necessary for uterine contractions in responce to oxytocin. |
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Term
|
Definition
This female hormone is produced & secreted after ovulation which lowers uterine activity when the female is in estrus or pregnant. |
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Term
|
Definition
This causes CL lysis which result in lower progesterone levels initiating a new estrus cycle. It should NOT be used in pregnant women. |
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Term
Growth Promoting hormones. |
|
Definition
Anabolic agents which improve efficiency in the rate of conversion from food to tissue. |
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Term
|
Definition
Used for tissue buildong in dogs, cats, & horses with anorexia, weight loss, and debilitation. Also promotes RBC formation. C-III controlled substance. |
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|
Term
Antisalogues
(saliva-stopping) |
|
Definition
Anticholinergic drugs which block the effect of ACh therby reducing GI motility & decreasing secretions. Ex: Glycopyrolate. |
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Term
|
Definition
A result of the intestinal tract's failure to adequately absorb fluids from intestinal contents. |
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|
Term
Antidiarrheals, probiotics, & antibiotics. |
|
Definition
These three types of medications help with diarrhea. |
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Term
|
Definition
These decrease peristalsis allowing fluid absorption. |
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Term
|
Definition
hese block ACh from the PNS nerve endings, thereby lowering GI secretions & motility, which helps with tenesmus. |
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Term
Protectants/ absorbents
(Antidiarrheals) |
|
Definition
A substance administered to absorb gases, toxins, bacteria, etc from GI tract. Exaples; Bismuth, activated charcoal. . |
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|
Term
Opiate-related agents.
(Antidiarrheal) |
|
Definition
Analgesics that control diarrhea by lowering intestinal secretions & flow of feces. Bringing up segmental contractions which bring up intestinal absorption. Example; Imodium. |
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Term
|
Definition
Preperations containing benificial bacteria that help re-seed the gut. Based on the theory that some diarrhea is due to the disruptpon of the normal GI flora. Ex; Plain yogurt, FortiFlora. |
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Term
|
Definition
Antibiotic that is effective against anaerobic bacteria. Used as an antidiarrheal on the theory that the normal flora may go higher then the number of anaerobic bacteria. |
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|
Term
Laxatives
(Stool Loosening) |
|
Definition
This class of drugs loosen the bowel contents & encourages evacuation of stool. |
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Term
|
Definition
This class of drugs includes these 4 categories; Osomotic, stimulant, bulk forming, & emollients. |
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|
Term
Osmotic Laxatives
(Hyperosmotics) |
|
Definition
This type of laxative uses salt to pull water into the colon thereby raising water content in the feces which will cause a rise in bulk & stimulate peristalsis. Example: Lactulose. |
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Term
|
Definition
This laxative can be used to lower amonia in liver disease patients. Not reccomended for cats & other aniamls wit CHF or CRF. |
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Term
|
Definition
This category of laxatives increases peristalsis. Example: Ducolax (Bisacodyl) |
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Term
|
Definition
This category of laxatives are natural or semi-synthetic substances that absorb water into the intestine, increase fecal bulk, stimlate peristalsis, & most contain psyllium, or plantage seed. xample: Metamucil, Bran |
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Term
|
Definition
This catagory of laxatives are stool softners which reduce stool surface tension, reduce water absoption through the colon & lubricate. Examples: Ducosate sodium (DDS) & mineral oil.
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Term
Antiemetics
(Vomit stopping) |
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Definition
This class of drugs helps control vomitting. |
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Term
|
Definition
Vomitting is controlled by this part of the brain with ACh ss the neurotransmitter. |
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Term
|
Definition
Which cranial nevre is stimulated to cause vomitting? |
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Term
Phenothiazine derivatives
(Antiemetics) |
|
Definition
This catagory of antiemetics inhibit dopamine in the CRTZ (Chemoreceptor trigger zone) decreasing stimulation to vomit. Examples: cepromazine, & Chlorpromazine. |
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|
Term
Antihistamines
(Antiemetics) |
|
Definition
This catagory of antiemetics is used in small animals to control motion sickness, vaccine reactions, & inner ear problems. They work to block input from vestibular system to the CRTZ. Examples: Benadryl, Dramaine. |
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|
Term
Procainamide derivatives
(Antiemetics) |
|
Definition
This cataory of antiemetics block the chmeoreceptor trigger zone & speed up gastric emptying They strengthen cardia sphinter tone and raise gastric contractions. Example: Reglan |
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|
Term
Serotonin Receptor Antagonists
(Antiemetics) |
|
Definition
This catagory of aniemetics block serotonin receptors peripherally & centrally. Examples: Zofran, Anzemet. |
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Term
|
Definition
This antiemetic drug is a neurokinin (NK1) receptor antagonist that is centraly acting. SQ and PO formulations. |
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|
Term
Emetics
(Vomit producers) |
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Definition
This class of drugs induce vomiting either centrally or peripherally. Used in the treatment of poisoning, toxicity, and drug overdose. |
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Term
|
Definition
This catagory of emeics stimulates dopamine receptors in the CRTZ. Examples: Apomorphine, Xylazine in cats. |
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|
Term
Periherally acting emetics. |
|
Definition
This catagory of emetic drugs cause irritation to the gastric mucosa & centrally stimulate the CRTZ. Example: Syrup of Ipecac. |
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Term
|
Definition
This class of drugs promote ulcer healing by neutralizing HCl & reducing pepsin activity. |
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Term
|
Definition
This catagory of antacids are absorbed into the blood. |
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Term
|
Definition
This catagory of antacids remain in the GI tract. Examples: Milk of magnesia, Maalox, Amphogel. |
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Term
|
Definition
This catagory of antacids prevent acid reflux by blocking H2 receptors of gastric parietal cells. Examples: Famotadine, Tagament, Zantac. |
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|
Term
Mucosal protectant antacids |
|
Definition
This catagory of antacids are pepsin inhibitors. Example: Sulcralfate (Carafate) |
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Term
|
Definition
This mucosal protectant antacid drug is a derivative of sucrose thats non-absorbable & combines with protein to form adherent substance that covers the ulcer. |
|
|
Term
Prostaglandin Analog antacids |
|
Definition
This catagory of antacids supress gastric secretions & raise mucus production in GI tract. |
|
|
Term
Proton Pump inhibitors (PPI's) |
|
Definition
This catagory of antacid drugs inhibits H ion transport into the stomach so cells can not secret HCl. Examples: Prilosec, Prevacid. |
|
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Term
|
Definition
This class of drugs reduce or prevent foam formation. Used in ruminants that are subject to frothy bloat. Examples: Polaxaline, Polymerized methyl silcone, & mineral oil. |
|
|
Term
Prokinetic Agents
(Motility enhancers) |
|
Definition
This class of drugs increase GI motility to enhance movement of material through it. Examples: Dopaminergic antagonists, parasympathomimetics, & serotonergc agents.
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Term
|
Definition
These may need to be supplemented into the dietof a patient with pancreatic exocine insufficiency. |
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Term
|
Definition
This class of muscle function drugs are used to reieve signs of redness, pain, swelling, heat, and decreased range of motion. Can be steroidal or non-steroidla. |
|
|
Term
Steroidal anti-inflammatories. |
|
Definition
This catagory of anti-inflammatory drugs are corticosteroids that have anti-inflammatory effects, Examples: Prednisone, Dexamethasone. |
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|
Term
Non-steroidal anti-inflammatories. |
|
Definition
This catagory of anti-inflammatory drugs are synthetic products that are unrelated to substances produced by the body. they inhibit prostaglandin synthesis. Eamples: Rimadyl, Metacam. |
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Term
|
Definition
This class of drugs is used to paralyze muscles. Given IV to paralyze muscles by disrupting the trasmission of nerve impulses from motor nerves to skeletal muscle fibers. Examples: Panacuronium, Neostigmine. |
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|
Term
Spasmolytics
(Spasm stopping) |
|
Definition
This class of drugs stop spasms. Used to treat accute episodes of muscle spasticity associated with neurological & musculoskeltal disorders. Example: Robaxin. |
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Term
|
Definition
This class of drugs can be used as prention or treatment for malignant hyperthermia. |
|
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Term
|
Definition
This claas of drugs promote tissue building which increases muscle mass. C-III controlled substance. Used also to promote growth, counteract post-surgical debility, & treat diseases such as muscle atrophy, & orthopedic conditions. |
|
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Term
|
Definition
his anabolic steroid can be used to stimulate RBC production. |
|
|
Term
Intracellular fluid
(ICF) |
|
Definition
Fluid within the cell. 2/3 of fluid in body. |
|
|
Term
Extracellular fluid
(ECF) |
|
Definition
Intrvacsular fluid and intestinal fluid together. 1/3 of fluid in body. Found in plasma and between cells. |
|
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Term
|
Definition
Sodium defficiency. Low Na intake or excessive loss through volume. |
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|
Term
|
Definition
Potassium deficiency. Low K intake over time, or loss through GI or urine. |
|
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Term
|
Definition
This route for fluid therapy is for short term illness on small animals and neonates. Given by tube, bottle feeding, nasogastric tube, or gastrostomy |
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Term
|
Definition
This route for fluid administration is for mild to moderate dehydration, not for large amounts of fluids. 5-10mls/lb Isotonic fluid only. No additives! |
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Term
|
Definition
This route for fluid administration is administered to the flank area or between scapulae but can really be given anywhere. |
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Term
|
Definition
Used for moderately to severe dehydrated animals, and hypovolemic animals. A catheter must be placed. Watch for fluid overload. |
|
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Term
|
Definition
Route used in small animals, birds, and pocket pets. Fluids go directly into bone marrow. |
|
|
Term
Femur( trochanteric fossa)
Humerous (greater tubercle) |
|
Definition
hen using the intraosseous oute, these bones are usually used. |
|
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Term
|
Definition
What must be avoided when administering an intraosseous injection? |
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Term
|
Definition
This route is used in young animals but not if they have diarrhea. It has great eletrolyte absorption but difficult to keep fluids in. |
|
|
Term
|
Definition
This route can be used as a last resort if you can not get a vein. |
|
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Term
|
Definition
This route is usually used on rats and mice. Useful if IV access is not available. Isotonic fluids. |
|
|
Term
Just lateral to midline. Between the umbilicus and pelvis. |
|
Definition
This is where an intraperitoneal injection should be administered |
|
|
Term
|
Definition
This tyoe of fluid is sodium based electrolyte solutions. Glucose in water. Similair to plasma fluid. Can be isotonic, hypotonic, or hypertonic. |
|
|
Term
|
Definition
Same as fluid component of blood and extracellular water. No change in osmolality of blood. |
|
|
Term
|
Definition
Lower osmolality of blood. May cause RBC swelling. |
|
|
Term
|
Definition
Jigher osmolality of blood. Causes RBC to shrink. |
|
|
Term
|
Definition
0.9% NcCl, Lactated ringers solution, Normosol, and Plasmalyte are akk eamples of what type of fluids? |
|
|
Term
|
Definition
5% dextrose in water(DSW), and 0.45% saline are examples of what types of fluids? |
|
|
Term
|
Definition
0.9% Na with 5% dextose, & 3% normal saline are examples of what type of fluids? |
|
|
Term
|
Definition
Signs of this problem include: dyspnea, tachypnea, fluid in the SQ space, or weight gain. |
|
|
Term
|
Definition
Fluids with large molecules. Caused fluid to move into vascular space. Increases osomotic oressure. |
|
|
Term
|
Definition
Plasma, albumin, and whole blood are what types of fluids? |
|
|
Term
|
Definition
This can be stored for years. It contains albumin and lobulins. Used in treatment of liver disease with coagulation factor deficienc. |
|
|
Term
|
Definition
Only human products available so must be careful and can be fatal. Type of colloid. |
|
|
Term
|
Definition
Increases HCT in anemic animals. Expires in 28-0 days. Blood typing is recommended. |
|
|
Term
|
Definition
This synthetic colloid is a large polysaccharide from sugar beets. Comes in 2 cncentrations: and 40 and 70.Example: Hetastarch. |
|
|
Term
|
Definition
Purified polymerized bovine hemoglobin. Distributes O2 via plasma rather than RBC's. Does not require blood typing or ross matching. Contraindicated with CHF. |
|
|
Term
|
Definition
In emergencies Atropine is used for? |
|
|
Term
Bolus 1/4 of shock dose.
Shock |
|
Definition
Crystalloid solution is used for what in an emergency? |
|
|
Term
Severe allergic reactions. |
|
Definition
Dexmethasone is used for what in emergencies? |
|
|
Term
Seizures
Status epilipticus |
|
Definition
Diazepam is used for what in emergencies? |
|
|
Term
|
Definition
Epinephrine is used for what in emergencies? |
|
|
Term
|
Definition
Doxapram is used for what in emergencies? |
|
|
Term
|
Definition
Lidocaine is used for what in emergencies? |
|
|
Term
|
Definition
Mannitol is used for what in emergencies? |
|
|
Term
|
Definition
Naloxone is used for what in emergencies? |
|
|
Term
Severe allerguc reactions |
|
Definition
Prednisone Sodium is used for what in emergencies? |
|
|