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Organic compound required in small amounts by an organism |
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B1 Food Sources: Lean Pork, Legumes, Whole grains, Brewer's yeast Required for alcohol oxidation |
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Alcohol, Folate Def, Protein Def |
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Wernicke-Korsakoff Syndrome |
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Form of Beriberi Major cause is ETOH |
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Yellow color, destroyed by exposure to light Sources: Dairy, eggs, meat, enriched breads and cereals |
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Occurs in combo with other BVit Def ANGULAR DERMATITIS |
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B3 Sources: Whole grain bread and cereal, milk, eggs, meat, dark veggies |
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Pellegra 4Ds - Dermatitis, Diarrhea, Dementia, Death Casal's necklace - symmetric |
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B6 Sources: Meats, cereals, legumes, lentils, nuts, fruits, veggies |
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Rare Characterized by weakness, irritability, nervousness, insomnia, difficulty walking |
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Loss of fine motor skills and ataxia |
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Found is basically all foods Sources: Organ meats, mushrooms, avocados, broccoli, whole grains |
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Panthothenic Acid Def/Tox |
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Present in all living cells Biotinidase frees biotin from protein bound form biocytin (biotin + leucine) |
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Seen only in genetically def biotinidase No Tox |
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Folate Sources: Meats, fruits, veg (asparagus), dry beans, peas, nuts, whole grains |
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Dermatitis, impaired growth Megaloblastic Anemia Neural Tube Defects - spina bifida and anencephaly |
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Overconsumption masks B12 def |
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B12 Foods of animal origin Must be bound to protein for abs |
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B12 With folate, makes homocysteine into methionine And can go other way |
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Pernicious Anemia (megaloblastic) No Tox |
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Vit C Sources: Citrus, Strawberries, Melons, Cabbage, Brussels Sprouts, Broccoli, Cauliflower |
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Antioxidant Protects Vit E |
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Scurvy
Relating to Iron/Folate: Fatigue, malaise, anemia |
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Critical for collagen production 1st sign of Def - impaired wound healing, joint pain, bone changes in infants, bleeding gums |
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May increase kidney stones through increased oxalate formation |
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Retinol/Carotene Retinol Sources - Red meat, liver, whole milk, cheese, butter Carotene sources - squash, carrots, peas, peaches, apricots |
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Keratinization: drying and hardening of epithelium of eye Xerophthalmia: all eye problems d/t vitamin A deficiency |
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Hypervitaminosis A Hypercarotenosis (yellow-colored skin) |
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Vit D Cod liver oil and fortification in milk Sunlight |
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Cholecalciferol converted to... |
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Definition
Must be converted to 25OH Vit D in liver (this is one in blood) Which must be activated in kidney to 1,25OH Vit D |
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PTH: Pulls Ca from bone 1,25OH Vit D: Deposits Ca into bone |
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Calcification of soft tissues |
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Megadoses may interfere with other Fat Sol Vit |
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Menaquinione Green leafy veggies |
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Blood clotting -Shot given at birth Bone formation |
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Well-absorbed Meat, esp. red meat |
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Not well-absorbed Legumes, raisins, prunes, molasses, fortified cereals, cooking in iron skillets |
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Tannins, soy proteins, phytates (type of fiber), Ca, Zn, Mn |
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Vit C, fructose, citric acid, stearic acid, HPro Foods |
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75% of Fe in blood as hemoglobin Binds O2 for transport in blood |
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Muscle protein that binds O2 for use |
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Anemia - Microcytic Most common nutritional def in world |
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Osteoporosis >2.5 SD Osteopenia Between 1 and 2.5 SD |
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Hypercalcemia - Only supplements Kidney Stones |
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Milk and Dairy, Meat, Legumes, Colas (except Root Beer), Whole grains |
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Hypophosphatemia Refeeding Syndrome Osteomalacia Muscle atrophy and weakness |
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Mineralization of soft tissues |
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Whole grains, nuts, green veggies |
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Oysters, Crab, Meat, Poultry, Milk, Nuts, Beans |
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Structure of Proteins - Zinc Finger |
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Dwarfism Hypogonadism Rough skin |
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Can interfere with Cu metabolism |
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Liver, oysters, clams, crabs, nuts, seeds, legumes |
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Uncommon, anemia unresponsive to Fe Supp |
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Menkes Steely Hair Disease Menkes Syndrome |
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Definition
Intestinal cells absorb Cu but does not release into circulation |
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Normal Cu absorption but low excretion into bile |
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Usually due to contamination of foods, water |
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Brazil Nuts, seafood, whole grains, organ meats |
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Selenium content heavily dependent on what? |
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Noted in LT TPN patients, PKU diets 1979 - Keshan disease is Se-Def China |
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Many symptoms, Garlic odor on breath is notable |
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Iodized salt, seaweed, fish and shellfish, milk, potato |
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Hypothyroidism: decreased resting metabolic rate Hyperthyroidism: increased RMR |
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Most common preventable cause of brain damage Goiter |
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