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Vitamins and Minerals
Module 4 Study Questions
75
Other
Graduate
05/19/2009

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Term
Phytate and oxalate inhibit zinc absorption by providing binding sites in the form of what element?
Definition
Oxygen
Term
Inhibition of zinc absorption by phytate can be reduced by what process?
Definition
Fermentation
Term
What effect does high intake of vitamin C have on copper absorption?
Definition
decreases
Term
Deficiency impairs taste sensation
Definition
zinc
Term
Participates in more enzyme systems than any other trace mineral
Definition
zinc
Term
Absorption facilitated by picolinic acid
Definition
zinc
Term
Absorption facilitated by citric acid
Definition
Both zinc and copper
Term
Absorption dependent on gastric hydrochloric acid
Definition
Both zinc and copper
Term
Mobilization of stores impaired by high iron intake
Definition
copper
Term
Blood concentrations rise during infection
Definition
copper
Term
Excessive accumulation in Wilson’s disease
Definition
copper
Term
Defective transport in Menkes syndrome
Definition
copper
Term
Mitochondrial electron transport
Definition
copper
Term
Alkaline phosphatase activity
Definition
Zinc
Term
Facilitates iron binding to transferring
Definition
copper
Term
Collagen cross-linking
Definition
copper
Term
Conversion of vitamin A for the visual cycle
Definition
Zinc
Term
Norepinephrine synthesis
Definition
copper
Term
Protein digestion
Definition
zinc
Term
Nucleic acid synthesis
Definition
zinc
Term
Do thionein polypeptides produced in response to zinc intake, have a higher affinity for copper or for zinc?
Definition
copper
Term
List the functions of metallothionein.
Definition
Intracellular binding ligand for copper
Impairs absorption of excessive dietary copper
Facilitates liver storage of zinc and copper
Scavenges superoxide and hydroxyl radicals
Intracellular binding ligand for zinc
Term
List the functions of ceruloplasmin.
Definition
Copper transporter
Oxidative enzyme
Antioxidant
Term
Does selenium exist in food only in the organic forms?
Definition
NO
Term
Are animal products generally considered better sources of selenium than plant products?
Definition
True
Term
How does the absorption of organic and inorganic forms of selenium compare?
Definition
Both are efficiently absorbed.
Term
Which form of organic and inorganic selenium is best absorbed from the gastrointestinal tract?
Definition
a) selenomethionine, b) selenate
Term
Associated with regional selenium deficiency in China
Definition
Both Keshan and Kashin-Beck disease
Term
Symptoms include cardiomyopathy
Definition
Keshan disease
Term
Symptoms include degeneration of joints and cartilage
Definition
Kashin-Beck disease
Term
Selenium deficiency is not likely the only causative factor
Definition
Both Keshan and Kashin-Beck disease
Term
What method was used to establish recommendations for selenium intake in the U.S?
Definition
Amount required to maximize plasma glutathione peroxidase activity
Term
What is the minimum intake of selenium that has been associated with the symptoms and biochemical signs of toxicity?
Definition
Amount required to maximize plasma glutathione peroxidase activity
Term
Which population group is most at risk for chromium deficiency?
Definition
Elderly
Term
Do phytates inhibit chromium absorption, selenium absorption, or both?
Definition
Both
Term
Substitutes for sulfur in amino acids
Definition
Selenium
Term
Trivalent form is most important in humans
Definition
Chromium
Term
High content in brewer’s yeast
Definition
Chromium
Term
Transported in the blood bound to transferring
Definition
Chromium
Term
Indicate the proposed influences and/or roles of chromium other than those associated with glucose tolerance.
Definition
Gene expression
RNA synthesis
Insulin potentiation
Term
Which vitamin enhances chromium absorption?
Definition
Vitamin C
Term
Consumption of what dietary component can raise urinary chromium excretion?
Definition
Simple sugars
Term
A mild chromium deficiency shares symptoms similar to Syndrome X except for which one?
Definition
Hypertension
Term
Iodine is added to what dietary component in order to help prevent iodine deficiency?
Definition
Salt
Term
What are goitrogens and where may they be found?
Definition
Lithium
Polycyclic hydrocarbons
Cabbage family vegetables
Term
How does iodine deficiency in infants differ symptomatically from maternal iodine deficiency?
Definition
While cretinism specifically refers to the consequences of maternal iodine deficiency, the severe neurological symptoms of cretinism appear only in the infant, not the mother.
Term
Which trace elements are essential for normal brain function?
Definition
Manganese
Term
Which trace element is involved with amino acid metabolism?
Definition
Arsenic
Term
Which micromineral is involved in sulfite metabolism?
Definition
Molybdenum
Term
Which trace element is involved in collagen formation?
Definition
Silicon
Term
Which trace element mimicks the action of insulin?
Definition
Vanadium
Term
Which micromineral is associated with the thyroid hormone thyroxine?
Definition
Iodine
Term
Which micromineral is required for mucopolysaccharide synthesis?
Definition
Manganese
Term
Which micromineral promotes the formation of hydroxyapatite?
Definition
Flourine
Term
Which trace element is a component of vitamin B12?
Definition
cobalt
Term
Gout is a symptom of overingestion of what micromineral?
Definition
Molybdenum
Term
Mottled teeth are a sign or symptom of overingestion of what trace element?
Definition
Fluoride
Term
Overingestion of what trace element is associated with kidney stones?
Definition
Silicon
Term
Green tongue is a sign or symptom from overingestion of what trace element?
Definition
Vanadium
Term
Which trace element is an antagonist to iodine and causes goiter?
Definition
Arsenic
Term
Which micromineral serves as a cofactor for xanthine oxidase in the metabolism of purines, pyrimidines, and pteridines?
Definition
Molybdenum
Term
Which trace element facilitates the use of ferric iron, but antagonizes ferrous iron absorption?
Definition
Nickel
Term
Which trace element is needed for glycosaminoglycan formation in joint tissue?
Definition
Manganese
Term
For which TWO minerals may nickel be an effective substitute in some enzyme systems?
Definition
Zinc
Magnesium
Term
How does the inorganic form of arsenic differ in toxicity from the organic form?
Definition
Inorganic forms of arsenic are more toxic than are organic forms of the element.
Term
Is hair analysis a good method to use for chronic exposure to excessive arsenic?
Definition
yes
Term
Indicate the tissue most influenced by boron.
Definition
Bone
Term
What are the best food sources of zinc?
Definition
Red meats and sea food
Term
What are the best food sources of copper?
Definition
Organ meats and shellfish
Term
Is zinc or copper more important for cytosol superoxide dismutase activity?
Definition
Copper
Term
Which forms of glutathione peroxidase are selenium-dependent
Definition
All?
Term
List the toxic metals known to interact with selenium in food or in the body
Definition
Iron copper and methionine (mercury)
Term
Does a selenium deficiency impair the effect of the thyroid hormone on adipose tissue? Why or why not?
Definition
Selenium is necessary for iodine metabolism – regulation of thyroid hormone – 5 types of proteins and 2,3 work on adipose tissue. So yes.
Term
List the best sources of fluoride.
Definition
Drinking water, grain, cereal products, fish and tea
Term
Boron affects the metabolism of which nutrients?
Definition
Phosphorus, calcium, vitamin D and magnesium
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