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Vision
Morrow 6/13/11 lecture 2 hrs
109
Histology
Undergraduate 4
06/06/2011

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Cards

Term
1) sclera
2) uvea
3) retina
Definition
what are the 3 main regions of the eye?
Term
cornea
Definition
what eye structure is included as part of the sclera region of the eye?
Term
choroid, ciliary body, iris
Definition
what eye strcture(s) are included as part of the uvea region of the eye?
Term
sclera
Definition
thick, opaque, white, outer fibrous covering of the eye
Term
aka the extrinsic eye muscles, they insert on the sclera
Definition
where do extraoccular muscles of the eye (ones that allow eye movement) insert on the eye?
Term
cornea
Definition
modified, transparent anterior portion of the sclera
Term
limbus
Definition
transitional zone between the cornea and sclera
Term
in the zone between the cornea and sclera known as the limbus
Definition
where is the canal of Schlemm found?
Term
drains the aqueous humor
Definition
what does the canal of Schlemm do?
Term
UV light makes the damage glow with fluorescien dye
Definition
what shows damage to the cornea? (the cornea can be damaged by abrasion, scratches, and ulceration)
Term
1) epithelium
2) Bowman's membrane
3) substantia propria (stroma)
4) Descemet's membrane
5) endothelium
Definition
what are the 5 layers of the cornea?
Term
non-keratinzed, stratified squamous epithelium
Definition
describe the outer surface of the cornea
Term
dense, regular, CT stroma (the substantia propria) containing fibroblasts called keratocytes
Definition
describe the layer that makes up the bulk of the cornea
Term
fibroblasts in the cornea that create typ 1 collagen in the substantia propria layer
Definition
what are keratocytes and where are they found?
Term
single layer of flattened endothelial cells
Definition
describe the posterior (interior) surface of the cornea
Term
type VIII
Definition
what type of collagen is in Descemet's membrane?
Term
fluid in the anterior chamber of the eye could leak out
Definition
why is it bad if Descemet's membrane is breached?
Term
stratified columnar epithelium (with a large number of goblet cells for lubrication)
Definition
what kind of epithelia covers the exposed sclera and inside of the eyelids?
Term
conjunctiva
Definition
a clear mucous membrane consisting of cells and underlying basement membrane that covers the sclera (white part of the eye) and lines the inside of the eyelids.
Term
conjunctivitis aka pink eye
Definition
if the inside of the eyelid and the exposed sclera become inflamed, what is this called?
Term
compound, tubuloacinar glands, similar to salivary glands
Definition
what kind of glands are the lacrimal glands?
Term
lysozyme
Definition
what is the antibacterial product secreted by lacrimal glands?
Term
lower eyelid, to the nasopharynx via the nasolacrimal duct
Definition
tear ducts at the medial canthus of which eyelid drain excess fluid in the eyes? to where? via what duct?
Term
skeletal muscle orbicularis oculi & levator palpebrae
Definition
name the muscle of the eyelid
Term
tarsus/tarsal plate
Definition
name the dense fibroelastic CT plate under the muscles of the eyelid
Term
Meibomian (tarsal) glands
Definition
name the oily glands in the eye-lid
Term
modified sebaceous glands that secrete oily product
Definition
what kind of glands are Meibomian glands?
Term
glands of Zeis and glands of Moll
Definition
name the 2 glands associated with the eyelashes
Term
Zeis = sebaceous glands
Moll = apocrine sweat glands
Definition
what type of glands are glands of Zeis? glands of Moll?
Term
uvea
Definition
middle vascular layer of the eye
Term
uvea
Definition
layer of the eye that nourishes the retina
Term
choroid, ciliary body, iris
Definition
name the components of the uvea
Term
between the sclera and retina
Definition
where is the choroid layer found?
Term
melanocytes that make melanin
Definition
what cells are found in the choroid layer that prevent the scattering of light to prevent glare?
Term
tapetum
Definition
name the blue/green/silvery layer of the eye that humans don't have that improves night vision and causes the "eye shine" phenomona
Term
no, they are not human
Definition
should you pick up a hitchiker, with a silvery glow in its eyes?
Term
central retinal artery and vein
Definition
name the vessel that supplies blood tot he retina and choroid
Term
along with the optic nerve, it divides and provides a unique branching pattern of retinal vessels, like a thumbprint
Definition
how do the central retinal artery and vein enter the eyeball?
Term
the central retinal vessel reflects light and causes a red glow inside the eye
Definition
what causes the red-eye effect on cameras?
Term
the ciliary body and iris
Definition
name the thickened anterior portion of the uvea
Term
smooth muscle
Definition
what kinf od muscle make up the ciliary body and the iris?
Term
the circumferential suspensory ligament aka/made up of zonula fibers (like parachute stings)
Definition
how does the ciliary body help suppor the lens (name the ligament)?
Term
melanin
Definition
zonula fibers are highly vascularized and pigmented with what?
Term
the iris
Definition
what surrounds the pupil and acts like an aperture that changes in size with changes in ambient light?
Term
constrictor pupillae, dilator papillae
Definition
name the muscle that constricts the pupil, name the one that dilates it.
Term
the amount of pigment in the stroma: small amount = blue, lots = brown
Definition
what determines the color of the iris?
Term
the lens changes shape to focus light on the retina via the muscles of the ciliary body
Definition
what allows for accomodation?
Term
they have no nuclei, and fill with crystallins that form lens fibers
Definition
describe the cells of the lens
Term
a thick basement membrane that forms the lens capsule
Definition
what surrounds the lens?
Term
aqueous humor in the anterior compartment
vitreous humor in the posterior compartment
Definition
which humor is in which compartment?
Term
the lens
Definition
what separates eye into the anterior and posterior compartments?
Term
the iris
Definition
what separates the anterior compartment into anterior and posterior chambers?
Term
thin watery = aqueous humor
thick = vitreous humor
Definition
which humor is thin and watery like CSF? which is thick and gel-like and supports the globe?
Term
the vitreous humor
Definition
what keeps the lens shape, eye shape, and keeps the retina glued down?
Term
secreted by the ciliary body, drains into the canal of Schlemm at the filtration angle
Definition
what secretes the fluid of the aqueous humor? what drains it?
Term
the aqueous humor
Definition
what provides nutrients to the lens and cornea since they are avascular structures?
Term
it is a non-refractile optical medium for light transmission so that light isn't distorted like when it goes through water
Definition
what is special about the aqueous humor involving refraction?
Term
retina
Definition
name the inner, photosensitive layer in the posterior eye that contains several layers of neurons and sensory cells
Term
the inner segments have organelles, the outer segments have stacked membrane-bound discs containing photoreceptor pigments
Definition
what is found in the inner and outer segments of the sensory cells of the retina?
Term
rods and cones
Definition
what are the 2 types of photreceptors?
Term
something that converts light energy into electrical impulses, the photoreceptors (rods and cones) do this
Definition
what is a transducer? what eye structures are transducers?
Term
rods
Definition
which photoreceptors are sensitive to light at 500nm (the green part of the spectrum)
Term
rods
Definition
which cells do nightvision, which is monochromatic vision?
Term
albedo
Definition
what do rod cells rely on to function (aka reflectance of light)?
Term
it is needed for visual purple(rhodopsin) which is a light sensitive chemical that allows your eye to adjust to light exposure
Definition
Why is vitamin A important for vision?
Term
exposure to light -> rhodopsin -> metarhodopsin -> retinal + opsin)
Definition
describe the light exposure/rhodopsin cascade
Term
cones, most mammals have dichromatic vision (2 types of cones for short and long wavelenghts) humans have trichromatic vision
Definition
what provides color vision? what do most mammals have? humans?
Term
S = short wavelengths, blue (425-450
M = med wavelengths, green (530-550)
L = long wavelenghts, red (560-600)
Definition
what are the 3 types of cones and their associated colors?
Term
UV reflectance patterns
Definition
some flowers have a ___ ____ ___ because insects have a 4th cone cell
Term
defects in cone cells
Definition
what causes color-blindness
Term
red-green (a form of dichromatic vision)
Definition
most common type of color-blindness
Term
it is x-linked (sex linked) so men are far more likely to get it
Definition
what is the inheritence pattern of red-green colorblind-ness?
Term
it is x-linked (sex linked) so men are far more likely to get it
Definition
what is the inheritence pattern of red-green colorblind-ness?
Term
protanopia (lack red cones)
deuteranopia (lack green cones)
Definition
what are the 2 types of red-green color-blindness?
Term
tritanopia
Definition
what do you call a person's disorder who lacks blue cones?
Term
-anomaly
Definition
if you have a decrease in the number of cones, it leads to color weakness . disorder of this type end in what suffix?
Term
achromatopsia
Definition
name the complete absence of cones and color vision
Term
1) neurons
2) pigment cells
3) support cells
Definition
name the 3 cell types of the retina
Term
1) cornea
2) aquesous humor of the anterior chamber
3) pupil
4) aqueous humor of the posterior chamber
5) lens
6) vitreous humor of posterior compartment
7) retina
Definition
describe the path of light as it enters the eye
Term
1) inner limiting membrane
2) afferent nerve fiber axons
3) ganglion cell layer
4) inner plexiform layer
5) inner nuclear layer
6) outer plexiform layer
7) outer nuclear layer
8) outer limiting membrane
9) photoreceptors
10) pigmented epithelial cell layer
Definition
name the layers of the retina as light would hit them
Term
inner limiting membrane
Definition
this layer of the retina is composed of expanded terminal processes of support cells (Muller cells)
Term
the optic nerve fiber layer (afferent nerve fiber axons)
Definition
this layer of the retina contains unmyelinated axons of ganglion cells on their way to the optic nerve
Term
ganglion cell layer
Definition
this layer of the retina is neuron cell bodies of the optic tract neurons with overlying axons on the way to the optic nerve
Term
inner plexiform layer
Definition
this layer of the retina is the synapses between interneurons and the optic tract neurons (ganglion cells)
Term
inner nuclear layer
Definition
this layer of the retina contains cell bodies of bipolar cells, amacrine cells, and horizontal cells
Term
outer plexiform layer
Definition
this layer of the retina contains synapses between photoreceptor axons and bipolar or horizontal cells
Term
outer nuclear layer
Definition
this layer of the retina is cell bodies of photoreceptors (rods and cones)
Term
outer limiting membrane
Definition
this layer of the retina is the layer of intercellular junctions between photreceptors and support cells (Muller cells)
Term
photoreceptors
Definition
this layer of the retina is the outer segments of rods and cones
Term
pigmented epithelial cell layer
Definition
this layer of the retina is a single layer of pigment cells containing melanin adjacent to choroid
Term
1) bipolar cells
2) horizontal cells
3) amacrine cells
Definition
what are the 3 types of integrating (inter) neurons?
Term
the inner nuclear layer
Definition
where are the 3 types of interneurons located in the retina?
Term
bipolar neurons
Definition
most numerous interneurons, make direct connections between photoreceptors
Term
horizontal cells
Definition
these interneurons provide lateral connections between photoreceptors
Term
amacrine cells
Definition
these internerons connect with bipolar neurons, optic tract neurons, and photoreceptors
Term
Muller cells
Definition
long, slender cells that extend from the inner limiting membrane to the outer limiting membrane
Term
Muller cells
Definition
analogous to the neruoglia of the cNS, they function as support cells, physically surrounded by axons of photoreceptor cells
Term
fundus (the opthalmoscope allows fundoscopic examination of the retina
Definition
name for the back of the eye
Term
ora serrata
Definition
anterior edge of the retina, just posterior to the ciliary body
Term
macula
Definition
in the center of the visual filed is a 1 sq mm spot on the retina with a concentration of cones known as the
Term
all cones, no rods, called the fovea centralis

this gives visual acuity
Definition
name the central portion of the macula, what cell type does it contain soley?
Term
fovea
Definition
no cell bodies or blood vessels overly cones in the central ____
Term
the optic disc (optic papilla)
Definition
a blind spot in the visual field where axons exit the retina into the optic nerve-no photreceptors are located there
Term
lamina cribosa
Definition
opening in the sclera for exiting axons
Term
glaucoma
Definition
increase intraoccular pressure due to increased production or decrease in drainage of aqueos humor that can lead to blindness
Term
cataracts
Definition
changes in the lens associated with aging due to cross linking of proteins leading to clouding of the lens
Term
macular degeneration
Definition
due to the accumulation of lipid within the choroid, leading to loss of cones int he macula
Term
presbyopia
Definition
age-related inability to change the shape of the lens during accomodation due to decreased reiliency
Term
retinal detatchment
Definition
due to retinal tears/head trama. treated by reattaching the retina with a laser
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