Term
who's the boss of visceral motor activity |
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Definition
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Term
what is another term for visceral motor system |
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Definition
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Term
what is the function of the visceral motor system |
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Definition
controls involuntary functions mediated by the activity of smooth muscle, cardiac muscle, and glands |
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Term
what are the 2 major divisions of the visceral motor system |
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Definition
sympathetic, parasympathetic |
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Term
funciton of sympathetic division of visceral motor system |
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Definition
mobilizes body's resources for dealing with challenges |
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Term
function of parasympathetic division |
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Definition
activity predominates during states of relative quiescence so energy can be restored: Rest and Digest |
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Term
where do parasympathetic preganglionic neurons origintate |
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Definition
either in the brainstem or in the sacral region of the spinal cord |
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Term
where do sympathetic preganglionic neurons originate |
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Definition
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Term
what are the 4 brainstem nuclei from which parasympathetic neurons arise |
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Definition
edinger-westphal nucleus, superior & inferior salivatory nuclei, dorsal motor nucleus of vagus, nucleus ambiguus |
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Term
which preganglionic parasympathetic neurons originate in the edinger-westphal nucleus |
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Definition
parasympathetic fibers of the oculomotor nerve (CN III) |
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Term
which preganglionic parasympathetic neurons originate in the superior and inferior salivatory nuclei |
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Definition
parasympathetic fibers of CN VII and IX |
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Term
which preganglionic parasympathetic neurons originate in the dorsal motor nucleus of the vagus |
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Definition
parasympathetic fibers of vagus |
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Term
which preganglionic parasympathetic neurons originate in the nucleus ambiguus |
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Definition
additional parasympathetic fibers that also project via the vagus nerve |
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Term
in what part of the brainstem is the edinger westphal nucleus |
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Definition
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Term
in what part of the brainstem is the dorsal motor nucleus |
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Definition
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Term
specifically where in the sacral spinal cord do parasympathetic preganglionic neurons arise from (what horn, what levels |
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Definition
lateral horn of the gray matter of spinal cord between S2-S4 |
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Term
what is the path of the preganglionic parasympathetic neurons that originate in the lateral honr of the gray matter of the spinal cord between S2-S4 |
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Definition
the axons of these neurons travel via pelvic splanchnic nerves to innervate parasympathetic ganglia in the lower 1/3 colon, rectum, bladder, and reproductive organs |
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Term
what nerve innervates the upper viscera |
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Definition
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Term
what innervates lower viscera |
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Definition
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Term
what are some parasympathetic activities |
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Definition
constrict pupils, slow heart rate, increase peristaltic activity of the gut, increase glandular secretions |
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Term
what is the enteric nervous system |
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Definition
an extensive system of independent nerve cells associated with the gastrointestinal tract |
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Term
do more neurons reside in the human GI tract or in the spinal cord? |
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Definition
more in the human GI tract |
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Term
if you want to consider that the visceral motor system has 3 divisions, what are its 3 divisions |
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Definition
sympathetic, parasympathetic, enteric |
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Term
what is the function of the Enteric Nervous System |
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Definition
enteric neurons work somewhat independently of the visceral motor system and help control mechanical and chemical conditions within the gut |
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Term
where are intrinsic enteric neurons located? |
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Definition
within the walls of the GI tract in 2 major plexuses: Auerbach's and Meissner's |
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Term
what are the 2 major plexues of the enteric nervous system |
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Definition
Auerbach's and Meissner's |
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Term
what is another term for Auerbach's plexus |
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Definition
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Term
what is the function of the neurons of the myenteric plexus |
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Definition
regulate peristalsis/muscular control of the guty |
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Term
what is another name for meissner's plexus |
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Definition
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Term
what is the function of neurons of the submucus plexus |
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Definition
chemical monitoring and glandular secretions |
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Term
what 3 neuronal systems control GI functions |
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Definition
enteric, parasympathetic, sympathetic |
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Term
where does parasympathetic innervation to the GI come from |
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Definition
dorsal motor nucleus of the vagus |
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Term
where does sympathetic innervation to the GI tract come from |
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Definition
sympathetic neurons from spinal cord byway of celiac and mesentary prevertebral ganglia |
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Term
can the enteric system function without vagus and without sympathetics |
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Definition
yes. It will still actively digest and move food along. |
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Term
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Definition
neurons that bring infromation back from viscera to CNS |
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Term
does the visceral motor system require sensory feedback? |
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Definition
yes: to modulate and control its many functions |
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Term
where are the cell bodies of many visceral afferents (GVA neurons) located |
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Definition
in small ganglia along the vagus nerve |
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Term
where do axons of GVA neurons project centrally |
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Definition
into the solitary nucleus of the brainstem |
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Term
what does the soliatary nucleus do once it has received sensory information from GVA neurons |
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Definition
integrates the sensory information and projects it onto the hypothalamus for further integration |
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Term
what is the key controlling center for autonomic function |
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Definition
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Term
what are some examples of visceral afferent information that the GVAs bring up to the CNS |
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Definition
nausea, GI distention due to overeating, pulse rate, respiration rate, blood pressure, how full the bladder/bowel is |
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Term
what is the major organizing center for visceral motor function |
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Definition
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Term
what part of the brain does the hypothalamus belong ot |
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Definition
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Term
what is the hypothalamus continuous with |
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Definition
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Term
what makes up the hypothalamus |
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Definition
large number of nuclei - each with their own pattern of connections and functions |
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Term
what is the key controlling center for general homeostatic funcitons |
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Definition
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Term
what is the path of GVA information, beginning with the vagus |
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Definition
vagus - NST - hypothalamus |
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Term
along with GVA information, what else projects to the hypothalamus |
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Definition
cerebral cortex amygdala, solitary nucleus |
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Term
what is another term for solitary nucleus |
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Definition
nucleus of the solitary tract = NST |
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Term
what does the hypothalamus do with all of the information/projections it receives |
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Definition
hypothalamic nuclei synthesize converging information and then project appropriate responses to preganglionic sympathetic and parasympathetic neurons in the brainstem and spinal cord |
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Term
what types of information does the hypothalamus integrate |
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Definition
visceral, cognitive, emotional |
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Term
what is the job of the hypothalamic nuclei |
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Definition
receive/integrate afferent stimuli and relay visceral motor responses |
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Term
describe the path of visceral info as it leaves organs as sensory and returns as motor |
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Definition
GVA from organs goes to the nucleus of the solitary tract. NST goes to hypothalamus. Hypothalamus integrates visceral sensory info with cognitive and emotional info. From the hypothalamus, it will activate either sympathetic or parasympathetic nerves to contro viscera. |
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Term
why is it that something I see can make me throw up |
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Definition
info from what you see goes to the hypothalamus. The hypothalamus controls vomiting centers |
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Term
what types of neurons leave the hypothalamus to go to the organs (GVA, GVE, GSA, GSE |
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Definition
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Term
from where (directly) does the hypothalamus receive visceral sensory information |
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Definition
nucleus of the solitary tract = NST |
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Term
is the hypothalamus the boss of sympathetics or parasympathetics |
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Definition
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Term
what are the basics of what the hypothalamus does |
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Definition
receives information from organs. Integrates it with cognitive/emotions. Sends direct responses down parasympathetics or sympathetics |
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Term
what 2 neurotransmitters does the visceral motor system use |
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Definition
acetylcholine and/or norepinephrine |
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Term
what is the primary neurotransmitter of sympathetic and parasympathetic preganglionic neurons |
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Definition
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Term
what are the 2 types of receptors that acetylcholine can activate on postganglionic neurons |
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Definition
nicotinic (nAChR) and muscarinic (mAChR) |
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Term
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Definition
ionotropic ion channels that mediate fast excitatory postsynaptic potentials |
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Term
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Definition
G-protein-linked receptors that mediate slower but prolonged postsynaptic potentials |
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Term
what neurotransmitter do sympathetic preganglionic neurons use |
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Definition
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Term
what neurotransmitter do parasympathetic preganglionic neurons use |
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Definition
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Term
which acetylcholine receptors mediate fast excitatory postsynpatic potentials on the postganglionic cell |
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Definition
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Term
which acetylcholine receptors mediate slow, prolonged postsynpatic potentials on the postganglionic cell |
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Definition
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Term
what is the result of acetylcholine being able to activate 2 kinds of receptors |
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Definition
preganglionic neurons can generate both rapid excitation and slower modulation on postganglionic neurons |
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Term
what kind of neurotransmitter is used by postganglionic sympathetic neurons |
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Definition
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Term
what is another term for norepinephrine |
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Definition
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Term
what kind of neurotransmitter is used by postganglionic parasympathetic neurons |
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Definition
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Term
why is the postganglionic sympatheticsystem sometimes referred to as an adrenergic system |
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Definition
postganglionic sympathetics release adrenalin/norepinephrine onto their targets |
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Term
why is the postganglionic parasympathetic system sometimes referred to as an cholinergic system |
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Definition
postganglionic parasympathetics release acetylcholine onto their targets |
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Term
what determines the specific effects of acetylcholine and norepinephrine from the postganglionic neurons |
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Definition
the type of receptor expressed on the target tissue |
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Term
from where does the heart receive sympathetic innervation |
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Definition
from neurons originating in the lateral horn of the spinal cord |
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Term
from where does the heart receive parasympathetic innervation |
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Definition
from neurons originating in the dorsal motor nucleus of the vagus |
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Term
what is the function of sensory receptors in the heart |
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Definition
sensory receptors monitor blood pressure changes in the great vessels and this information is conveyed via vagus nerve to the NST |
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Term
what sensory receptors are in the heart |
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Definition
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Term
what neurotransmitter is released by preganglionic parasympathetic neurons that synapse on the heart |
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Definition
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Term
what happens if blood pressure increases? |
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Definition
deformation of baroreceptors in the great vessels is conveyed through the vagus nerve GVA fibers to the nucleus of the solitary tract. The NST relays this information to the hypothalamus for integration. The hypothalamus responds by inhibiting preganglionic sympathetic neurons in the spinal cord as well as by activating preganglionic parasympathetic neurons in the dorsal motor nucleus of the vagus. Inhibition of sympathetic neurons and activation of parasympathetic neurons prevents release of norepinephrine and causes a release of acetylcholine, thereby decreasing herat rate |
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Term
what is the result of inhibition of preganglionic sympathetics to the heart |
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Definition
reduced stimulation of postganglionic sympathetics and therefore reduced stimulatory effect of norepinephrine on cardiac muscle |
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Term
what is the result of activation of preganglionic parasympathetic neurons |
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Definition
activation of postganglionic parasympathetic acetylcholine release decreases heart rate and force of heart contractions |
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Term
bladder is under control of what 3 systems |
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Definition
somatic, sympathetic, parasympathetic |
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Term
what is the function of sympathetic activity on the bladder |
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Definition
throughout the day, tonic sympathetic activity closes the internal sphincter and allows the bladder to fill |
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Term
what is the function of somatic innervation to the bladder |
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Definition
somatic motor nerve (pudendal nerve) tonically closes an external sphincter to prevent voiding |
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Term
what are the nerve roots of the pudendal nerve |
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Definition
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Term
what is the pathway that tells you that you need to pee |
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Definition
as the bladder fills, visceral afferent neurons project to the spinal cord and ultimately to the nucleus of the solitary tract and pontine micturation centers in the brainstem |
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Term
what is the pathway that allows you to release urine from the bladder |
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Definition
hypothalamus/pontine micturation centers initiate descending pathways which inhibit the sympathetics and the pudendal nerve, which have been closing the sphincters. The hypothalamus/pontine micturation centers activate parasympathetics in the S234 spinal cord which cause bladder contraction. |
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Term
if you have a spinal cord injury, how do you release urine from your bladder |
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Definition
the ascending sensory information from the bladder as well as the descending motor information to the bladder has been cut off. However, once you get enough volume in the bladder, urination is stimulated reflexively by parasympathetic nerve at the sacral spinal cord level, causing bladder to empty incompletely |
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Term
what is the problem of incomplete emptying of the bladder in SCI patients |
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Definition
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