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Viruses. The Final Chapters
Well, its half of the final exam unfortunately. Mr. Brady, LCCCCCCC
81
Microbiology
Undergraduate 2
05/05/2014

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Term
Ivanowski
Definition
Dude that coined the term "filterable virus"
Term
Tobacco Mosaic Virus (TMV)
Definition
"First" virus, helical capsid
Term
Bacteriophage
Definition
Virus that kills bacteria.
Term
Viroid
Definition
Naked circles of RNA that attack PLANTS
Term
Prion
Definition
Smallest agents of disease
Proteins, not nucleic acids
ex diseases: Creutzfeldt-Jakob Disease, Bovine Spongiform Encephalitis, and Kuru
Term
Creutzfeldt-Jakob Disease, Bovine Spongiform Encephalitis, and Kuru
Definition
Examples of Prion diseases. Dammit.
Term
Virion
Definition
Term for an individual virus particle
Term
Virus
Definition
Infectious, noncellular particles which can redirect the metabolism of living cells
Term
Lack organelles
No metabolism, can't make ATP
Only one type of nucleic acid
Can't reproduce by themselves
Definition
General info about viruses
Term
Envelope
Definition
Piece of the host cell membrane taken by the virus when it kills the cell; not all viruses have it
Term
Core (Nucleic Acid)
Covering (Capsid and Envelope)
Definition
Components of a virus
Term
Capsid
Definition
All viruses have it, it surrounds the core
Term
Capsomers
Definition
building blocks of a capsid
Term
Natural Killer Cells
Definition
Cells that can detect and kill the virus even when it has an envelope
Term
Neutrophil
Definition
WBC that can't detect a virus when its enveloped
Term
Helical Capsids
Definition
Rod shaped capsomers, "slinky", example = TOBACCO MOSAIC VIRUS
Term
Polygon Capsid
Definition
capsid shapes look geometric "daisy death star" Hexon, Penton
ex. Polio, adenovirus
Term
Hexon capsomer
Definition
form sides of a geometric capsid
Term
Penton capsomer
Definition
Form corners of a geometric capsid
Term
Naked virus
Definition
type of virus that has no envelope
Term
enveloped virus
Definition
type of virus that has an envelope
Term
Complex virus
Definition
POX virus - large with a DNA core, no real capsid, just layers of lipoproteins
Term
Capsid (Contains Nucleic Acids)
Collar + Sheath (inject nucleic acid)
Tail Fibers (for attachment)
Tail Pins (also attachment)
Definition
Parts of a bacteriophage
Term
3210
Definition
Jimmy Neutron's House Address
Term
DNA Viruses
Definition
6 Families
Smallpox, Herpes simplex, Epstien-Barr, Adenovirus, Papillomavirus, Hepatitis B, Parvovirus
Term
RNA Viruses
Definition
13 Families, includes Hep A, poliovirus,rhinovirus, rubella, ebola, hanta, influenza, rabies, AIDS
Term
rhabdovirus
Definition
virus is bullet shaped, causes rabies
Term
togavirus
Definition
virus looks like it has a cloak- west nile virus
Term
adenovirus
Definition
virus attacks glands
Term
rhinovirus
Definition
virus attacks nose, common cold, nonenveloped RNA
Term
picornavirus (pico-RNA-virus)
Definition
a very small RNA virus
Term
reovirus (Respiratory Enteric Orphan viruses)
Definition
virus that causes no known disease
Term
Lytic cycle
Definition
Series of steps in which a virus enters the cell and DESTROYS IT
Term
Virulent Phage
Definition
Virus that does the Lytic cycle- enters and destroys cells
Term
Penetration
Duplication
Assembly
Maturation
Lysis
"Penetrate, DAM!, its destroyed"
Definition
Steps of lytic cycle in order
Term
Lysozyme
Definition
Enzyme in bacteriophage that digest the pilus
Term
"Ghost" of the Bacteriophage
Definition
An empty capsid on the outside of the cell
Term
Eclipse Period
Definition
When the virus is inside the host cell and cannot be detected, harder for WBCs to detect/destroy
Term
Lysogenic Cycle
Definition
A series of steps where the virus DOES NOT DIRECTLY KILL
Term
Temperate Phage
Definition
Does the lysogenic cycle (does not directly kill)
Term
Prophage
Definition
Viral DNA which has gone dormant, wait for trigger
Term
Lysogenic bacterium/cell
Definition
contains the prophage
Term
Poxvirus
Definition
produce skin pustules which leave depressed scars, Enveloped DNA virus
Term
Smallpox and cowpox, not chicken pox
Definition
Examples of pox viruses
Term
Variola minor / Variola major
Definition
Forms of small pox
Term
Macular
Definition
flat pox rash
Term
papular
Definition
raised pox rash
Term
vesicular
Definition
fluid filled pox rash
Term
pustular
Definition
dead cell filled pox rash
Term
Herpesvirus
Definition
produces creeping rash, loose fitting envelope - 2 types
Term
HSV1 - labialis or Ocular herpes
HSV2 - Herpes genitalia (STD)
Definition
2 types of herpes
Term
Varicella-Zoster Virus (VCV)
Definition
Causes chicken pox and shingles, airborne, vaccine = Varivax
enveloped DNA virus
Term
Reye's Syndrome
Definition
Severe complication of chicken pox linked with asprin
Term
Shingles
Definition
VCV goes dormant on spinal or facial nerve
Corticosteroids or gaba protein used in treatment
Term
Ebstein-Barr Virus (EBV)
Definition
Infectious mononucleosis, enveloped DNA virus
Term
Burkin's lymphoma
Definition
Lumpy Jaw w/ EBV, aflotoxin, malaria, milkbush
Term
Aflotoxin
Definition
builds on moldy peanuts, linked to burkins with EBV
Term
Hepadnavirus
Hep B
Definition
Attacks liver, jaundice, vaccine is HBIG
Enveloped DNA Virus
Term
Adenovirus
Definition
Common cold, nonenveloped DNA virus
Term
Papovavirus
Definition
causes warts, STD condyloma acuminate, nonenveloped DNA
Term
papillomas, verrucas, warts
Definition
3 words for wart
Term
Jaundice
Definition
Yellowing of skin (Hep)
Term
Parvovirus
Definition
Smallest virus, causes erythema contagiosium - infectious in children. nonenveloped DNA
Term
Paramyxovirus
Definition
mumps or parotitis, RNA Enveloped Virus, viremia, meningitis, orchitis
vaccine = MMR
Term
Morbillivirus
Definition
measles (rubeola), kopliks spots, mmr, RNA enveloped
Term
Rhabdovirus
Definition
rabies, enveloped RNA virus, neurotropic, negri bodies, vaccine HDCV Imovax, RVA
Term
Neurotropic
Definition
attacks nerves
Term
Negri bodies
Definition
masses of virions in the neurons appearing as black spots in spinal cord
Term
Rubella
Definition
Togavirus that causes German measles, makes monsters, RNA enveloped
vaccine = MMR
Term
Flavivirus
Definition
Togavirus, West nile and Yellow fever, enveloped RNA, Vector = Culex Mosquito
Term
Culex Mosquito
Definition
Vector for the Togavirus, Flavivirus
Term
Aedes aegypti
Definition
Vector for yellow jack
Term
attenuated yellow fever
Definition
yellow jack/ yellow fever vaccine
Term
Retrovirus
Definition
Contain Reverse transcriptase
Term
HIV
Definition
Retrovirus, Lentivirus, enveloped RNA, infects macrophages and lymphocytes - esp helper T cells, Latent period
Term
Ebola
Definition
Filoviridae, Enveloped RNA, explosive destruction of immune system
Term
Maburg virus
Definition
sever hemmorhagic fever, zoonotic, enveloped RNA
Term
Bunyaviridae
Definition
Hantavirus, Hemorrhagic fever, enveloped RNA
Term
Orthomyxoviridae
Definition
Influenza, 3 Types ABC
Term
Enterovirus
Definition
Nonenveloped RNA, picornavirus, polio, vaccine - Salk or Sabin
Term
HepA
Definition
Nonenveloped RNA that affects liver
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