1. Attachment: host specificity
- virus attaches to the animal cell
2. Penetration: virus enters the cell membrane
- "naked" virus = no membrane
- enter the eukaryotic cell by pinocytosis - active cellular process by w/c nutrients and other mol. are brought into a cell
- virus w/ memb. fused w/ cell memb.
- fusion in w/c the viral envelope fuses w/ the plasma memb. and releases the capsid into the cell's cytoplasm
- virus w/ memb. fused w/ cell memb. by phagocytosis
3. Uncoating: viral genetic material released fr. capsid; capsid is:
- digested in vesicles or released fr. vesicles
- digested in cytoplasm or
- digestion while still attached to cell memb.
4. Biosynthesis:
- transcription of the DNA = produce mRNA
- replication of the viral DNA = some viral proteins are made
- translation = ribosomes use mRNA to make proteins
5. Assembly: proteins capsid is assembled
- release: when a portion of the plasma memb., now the envelope, adheres to the virus
- budding: when envelope develops around the capsid/viruses
- proteins of virus
- membranes of host
- lysis: naked viruses
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