Term
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Definition
| maintenance of virus genotype from generation to generation |
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Term
|
Definition
emergence of new viral strains
new biological properties
consequence of mutation and selection |
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Term
|
Definition
| Swapping of homologous sequences between two strands |
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Term
|
Definition
| 2 sequences mix and Progeny viruses are either type 1, type 2, or a hybrid of both |
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Term
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Definition
lethal mutation
silent mutation
persistence disadvantage
persistence advantage |
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Term
Influenza A
(orthomyxovirus) |
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Definition
Envelope glycoproteins: Haemagglutinin, Neuraminidase
Genome - 8 linear RNA segments |
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Term
|
Definition
major Ag for neutralising Ab
binding host receptors |
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Term
|
Definition
| release of progeny virus from cell surface |
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Term
|
Definition
| All aquatic avians are hosts all all 16 H and all 9 N subtypes |
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Term
|
Definition
spontaneous mutations in surface antigens from selection of variants in a partially immune population
Seen in SEASONAL FLU |
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Term
|
Definition
major change in surface antigenicity [due to process termed reassortment]
Pandemic flu – emergence of strains with new antigenic type (esp H) to which population has no prior immunity |
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Term
| Emerging/re-emerging disease |
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Definition
| pathogen that is newly recognised or newly evolved, or that has occurred previously but shows an increase in incidence or expansion in geographical, host or vector range |
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Term
|
Definition
| spread of disease to many people |
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Term
|
Definition
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