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- Papovaviruses - Adenoviruses - Herpesviruses - Cytomegaloviruses - Epstein-Barr Virus (EBV) - Varicella Zoster Virus - Poxvirus |
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- most common infection = Verrucae (skin wart) |
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- URI – common cold - Pharyngoconjunctival fever, conjunctivitis - Epidemic keratoconjunctivitis - Pneumonia - sometimes |
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- Type 1 (80% lips 20% genital) and type 2 (80% genitalia, 20% oral) - Human the only known reservoir - Direct contact - Herpes labialis and genitalis - Sporadic fatal encephalitis |
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- Neoplastic, transplant, immunosupressed |
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- Infectious mononucleosis (Kissings disease) – enlarged and tender lymph nodes, fever, sore throat, disease of teenagers and young adults - Heterophile antibody- diagnostic test - African form of burkitt’s lymphoma, nasopharyngeal carcinoma - nasal swab for EBV, then if positive, endoscopy for CA |
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- Chicken pox and herpes zoster (shingles) - don't need to culture, just treat |
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- Molluscum contagiosum - KIDS - Skin disease afflicts children and young adults - Shiny papules on skin and mucous membranes - Self limited - goes away - Good hygienic practices |
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- Consists of one group - Influenza viruses - Immunologic types A,B,C based on projecting glycoproteins that has hemagglutinin activities (HA) and neuraminidase activity (NA), H and N - High frequency of antigenic variation - Antigenic drift and antigenic shift (major change) - Minor shift – endemic, major shift - epidemic |
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- Influenza A viruses - Most prone to antigenic change - Four shifts since 1933 - Hemagglutinin inhibition (HA) and neuraminidase inhibition (NA) - H0N1 > H1N1 >H2N2 > H3N2....H5N1 - Pandemic influenza A (H1N1) first reported in Mexico, 18,000 deaths MOST COMMON |
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- Interpersonal transfer of influenza by sneezing or coughing - Aerosolization, nursing home, classrooms, ships - Epidemic spread in populations that partial immunity |
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- sudden onset high temperature>102, myalgia, sore throat, headache, cough, anorexia, and potentially pneumonia - do not give bed rest and fluids, give tamiflu |
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- adenovirus, RSF, coronavirus, parainfluenza, rhinovirus |
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- Parainfluenza viruses – larygotracheobronchitis (croup), bronchiolitis and PNA - Mumps virus - parotitis - Measles virus - Respiratory syncytial virus |
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- Polioviruses – spinal poliomyetlitis - Coxsackieviruses – myositis and herpangina (fever, headache, sorethroat, stiffneck, anorexia) - Echoviruses – aseptic meningitis and enteritis, rash, rare - Rhinoviruses – common cold (most common cause) |
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Patient comes in w/ diffuse rash...no temperature, don't look too sick, still active, good appetite, had rash for last 3 days |
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Definition
- virus - most likely echovirus, coxsackivirus - no treatment |
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rare causes of meningitis |
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- people die of hematological changes causing hemorrhage - decoagulation problem - fever, nausea and vomiting, headache, muscular pain, malaise, inflammation of the pharynx, and diarrhea accompanied with bloody discharge, and the development of maculopapular rashes along with bleeding at other body orifices |
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- Adenovirus, RSV, coronaviruses, parainfluenza, rhinoviurses are easily confused |
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