Shared Flashcard Set

Details

Viruses
IDIT3
6
Medical
Professional
02/07/2011

Additional Medical Flashcards

 


 

Cards

Term
Will people who are hetero for CCR5 get HIV?
Definition
Yes. Progression will just be slower
Term
How does HIV bind to the host cell?
Definition
GP 120 binds to CD4 receptor and Chemokine receptor
GP 41 is the stalk of the lollipop, F-protein
Term
What are the chemokine receptors needed for HIV inf?
Definition
Cxcr4 and CCR5
Term
What is the end result of syncytium?
Definition
giant cells. multinucleated cells
Term
Three major genes that encode polyproteins for structural and enzymatic prots in HIV
Definition
GAG- group specific antigen, capsid proteins
POL- polymerase (RT), integrase, protease
Env-envelope glycoproteins; SU(gp120), TM (gp41)
Term
Progression on HIV
Definition
stage 1: spike in Viral counts
Stage 2: the CD4 and T cell count decreases and Viral count is low
Stage 3: Anti-HIV1 Ab counts drop and CD4 and T cells are really low... viral counts increase
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