Term
| 4 acute neurological syndromes |
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Definition
| encephalitis, meningitis, post-infectious encephalomyelitis, flaccid paralysis |
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Term
| 4 chronic neurological conditions |
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Definition
| SSPE, PML, TSE, retrovirus diseases |
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Term
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Definition
| togaviridae, flaviviridae |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| G protein is required for adsorption; virus? |
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Definition
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Term
| M protein is required for budding |
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Definition
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Term
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Definition
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Term
| ascending paralysis, convulsions, no sphincter control; dx? |
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Definition
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Term
| dysphagia, hydrophobia, hyperexcitability, insomnia, delirium; dx? |
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Definition
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Term
| 1. host receptor for rabies virus 2. for CMV |
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Definition
| 1. nicotinic ACh receptors 2. C3d |
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Term
transmission of...
1. filovirus
2. of EEE |
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Definition
1. direct contact
2. Culiseta bird to Aedes mosquito |
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Term
| active and passive immunization is available for... |
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Definition
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Term
| production of N protein is [more/less] than production of L protein in rubeola virus |
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Definition
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Term
| replication in lymphoid tissue, primary viremia 2d post-exposure, then secondary viremia 7d post-exposure (symptom onset); bug? |
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Definition
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Term
incubation time for...
1. rabies
2. measles
3. mono |
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Definition
1. rabies: months to years
2. measles: 10d
3. mono: 6 wks |
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Term
| child with maculopapular rash that begins on face and head and becomes confluent; dx? |
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Definition
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Term
| complications of measles (5) |
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Definition
| encephalites (PIE, MIBE, SSPE), pneumonia, otitis media, ocular defects, immune suppression |
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Term
1. what disease occurs weeks post-measles infection?
2. months?
3. years? |
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Definition
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Term
| AIDS pt presents with myoclonus and convulsions and hx of viral infection; dx? |
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Definition
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Term
| autoimmune demyelinating disease with antibodies against MBP; dx? |
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Definition
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Term
| high anti-measles titers in CSF; personality changes, poor schoolwork; dx? |
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Definition
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Term
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Definition
| lack of M protein or mutant M protein creates a variant measles strain that is not cleared |
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Term
| genome and structure of JC virus |
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Definition
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Term
| chronic demyelination that is fatal within 3-6mo; latent in brain, kidney, and B cells; dx? |
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Definition
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Term
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Definition
| temporal lobe and olfactory cortex |
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Term
| what strains are more likely to cause HSV encephalitis? meningitis? |
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Definition
| HSV-1 -> encephalitis. HSV-1 and 2 -> meningitis |
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Term
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Definition
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Term
latency location for...
1. VZV
2. Japanese encephalitis
3. JC virus |
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Definition
1. trigeminal ganglion or DRG
2. lymphocytes
3. brain, kidney, B cells |
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Term
| what viral infections present only in immunocompromised pts? (3) |
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Definition
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Term
| clinical presentation of congenital CMV (8) |
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Definition
| epileptic, retarded, blind, deaf, hemolytic anemia, thrombocytopenic purpura, jaundiced, small for gestational age |
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Term
| 50% of pts have cold agglutinins, autoimmune hemolytic anemia, and mild thrombocytopenia; dx? |
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Definition
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Term
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Definition
| humoral and cellular; dsRNA elicits IFN response |
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Term
| what diseases do we have vaccines for the vector but not human? (4) |
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Definition
| EEE, WEE, VEE, Japanese encephalitis |
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Term
| severe disease in <1yo; commonly asymptomatic in adults; dx? |
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Definition
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Term
| fever, rash, polyarthritis; transmitted by rodent and mosquito; dx? |
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Definition
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Term
| age range affected by LaCrosse encephalitis and clinical S&S |
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Definition
| <16yo, subclinical (fever, flu-like) |
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Term
| which arbovirus is not arthropod borne? |
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Definition
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Term
| hemorrhagic fever and renal disease in Korea but lung disease in US; dx? |
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Definition
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Term
1. MRI shows symmetrical high signal in pulvinar; dx?
2. MRI shows bilateral high signal in anterior basal ganglia; dx? |
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Definition
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Term
| age range for TSE and clinical presentation |
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Definition
| 40-70yo with rapid neurological degeneration, spongiosus on gross, amyloid plaques on biopsy |
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Term
| encephalites that are particularly fatal (3) |
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Definition
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