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1) Adherence factor 2) Anti-phagocytic 3) Antigenic (leads to antibodies) |
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Activates plasmin to dissolve clots to facilitate spread |
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Breaks through connective tissue/proteoglycans |
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Streptococcus pyrogenic toxin |
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Definition
Activates the mediators of sepsis, such as IL-1 |
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Definition
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Binds IgG, preventing phagocytosis |
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Allows fibrin formation around organism |
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Definition
Inhibits release of GABA and glycine inhibitory neurotransmitters |
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C. perfringens: Alpha toxin- lecithinase |
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Definition
Splits lecithin in phosphocholine and diglycerides |
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Inhibits acetylcholine release |
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Definition
1) A-subunit: blocks eukaryotic protein synthesis by inactivating EF2 2) B-subunit: provides entry into cardiac and neural tissues |
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Term
Listeriolysin O and phospholipase |
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Definition
Allows escape from phagolysosome |
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