Term
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Definition
Poxviridae
Iridoviridae
Asfarviridae
Herpesviridae
Adenoviridae
Polyomaviridae & Papilloviridae |
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
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Definition
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Term
| Negative sense ss RNA viruses |
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Definition
Bornaviridae
Rhabdoviridae
Filoviridae
Paramyxoviridae
Bunyaviridae
Arenaviridae |
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Term
| Positive sense ss RNA viruses |
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Definition
Calciviridae
Picornaviridae
Coronaviridae
Arteriviridae
Flaviviridae
Togaviridae |
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Term
| Coding regions for the viral genome |
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Definition
ORF
Non structural proteins
Structural proteins
Virulence factor |
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Term
| Non coding regions often referred to as untranslated region of the viral genome |
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Definition
Scaffolding structural elements
Regulatory elements
Non coding regions can function as virulence factors |
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Term
| Increased by interferons to shut down translation of virus infected cells |
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Definition
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Term
| B-cell memory is an active process maintained by the________, located in the lymph nodes. |
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Definition
| Follicular dendritic cell (FDC) |
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Term
| All sources of influenza come from? |
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Definition
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Term
| How does NS1 block the invasion of influenza? |
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Definition
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Term
| Alpha herpes virus uses what strategy for evading host mechanisms? |
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Definition
| Latency- hides in ganglia |
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Term
| Additional desirable properties of a vaccine? |
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Definition
Stable
No shedding of virus
Sustained protection
Contain compliance marker
Resistant to maternal antibody |
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Term
| For inactivated vaccines induction of __________ is key to preventing infection. |
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Definition
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Term
| Vaccinations for maximum safety? |
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Definition
Inactivated (killed) virus
Subunit vaccine |
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Term
| Vaccines for maximum efficacy? |
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Definition
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Term
| Targets the genome replication of herpes virus? |
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Definition
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Term
| 3 classes of retrovirus drugs |
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Definition
Nucleoside analog RT inhibitors
Non nucleoside analog RT inhibitors
Protease inhibitors |
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Term
| Disadvantages of electron microscopy? |
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Definition
Expensive
Technical requirements
Lack sensitivity |
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Term
| Cell cultures with a finite life span? |
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Definition
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Term
| Cell cultures that can live indefinitely? |
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Definition
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Term
| A lytic event for the infected cell caused by a type of virus infection; lacks specificity so it can't distinguish viruses. |
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Definition
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Term
| Which is more specific CPE (cytopathic effect) or FA (fluorescent antibody)? |
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Definition
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Term
| Most informative serological assay about "protective antibodies"? |
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Definition
| Serum Neutralization test |
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Term
| Growing virus up into a large quantity and breaking it down into a protein profile for DIVA is what test? |
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Definition
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Term
| Why develop a DIVA assay? |
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Definition
Eradication
Ring vaccinated for FAD |
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Term
| This binds to a receptor on a cell and induces the syntheses of proteins that place the cell in a virus resistant state? |
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Definition
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Term
| What signals the nucleus to make interferon? |
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Definition
| TLRs after a PAMP binds to it |
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Term
| The two categories of Acquired immune response? |
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Definition
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Term
| The 3 parts of Innate Immunity? |
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Definition
RNAi
Interferons and other cytokines
NK cells |
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Term
| The genome can be translated into protein directly |
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Definition
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Term
| A complementary copy must be made first |
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Definition
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Term
| All members of this family use reverse transcriptase for the initial steps of replication? |
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Definition
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Term
| In the penetration/uncoating stage what are the two ways viruses enter the cell? |
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Definition
Endocytosis
Membrane fusion |
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Term
| Assay that determines "serotypes" |
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Definition
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