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Definition
naked capsid-cubic
large DNA virus
protein inhibits signal trandsuction pathway for interferon
+-DNA
use of protein primer for end problem→add terminal protein + viral DNA pol→ dCTP? →dNTP’s displacement synthesis
blocks activation of PKR |
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Term
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Definition
code for own DNA polymerase
concatemers by recombination by two concatemer dimers
early-RNA pol + alt protein + mod protein
middle-RNA w/adp ribose + mot A protein
late-RNA + T4 sigma factor
large DNA virus
+-DNA virus |
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Term
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Definition
code for own DNA pol
terminal redundancy to form concatemers
+-DNA virus |
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Definition
dsRNA virus
semiconservative |
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Definition
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Definition
| uses host DNA synthesis machinery |
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Definition
hanta virus
+-ambisense, resemble -strand translate - strand to +mRNA to make transcriptase/replicase |
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Definition
mouse hepatitus and SARS
+ strand RNA virus: antigenome to make more + strands |
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M13 and fd
use host DNA machinery, ss circular DNA
-DNA |
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Definition
hep C-binds PKR to inhibit, west nile
+RNA |
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Definition
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Definition
| protein inhibits signal transduction pathway |
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Definition
herpes simplex-enveloped cubic and direct fusion
is an analog that blocks activation of RNase L and removes phosphate to not prevent the initiation of translation
epstein barr-proteins inhibit signal transduction for interferon and blocks activation of PKR
HSV-binds dsRNA to antagonize interferon
code for own DNA pol |
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Term
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Definition
influenza A
receptor mediated by enveloped, segmented
genome
-RNA virus by cap snatching and splicing mRNA
protein blocks binding of RIG-1
inhibits PKR |
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Term
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Definition
code for own DNA pol
ds circular DNA |
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Definition
SV40, polyoma
uses host DNA, ds circular DNA |
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Definition
measles, sendai
direct fusion
-RNA virus
- strand RNA |
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Term
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Definition
adeno-associated AAV
hairpin ends(self priming palindromes), sequence specific endonuclease cleavage, displacement synthesis
protein primers for end problem
eukaryotic DNA virus-monocistronic |
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Term
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Definition
vaccinia
code for own DNA pol
binds dsRNA to antagonize interferon
continuous ends for solution to end problem |
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Term
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Definition
segmented genome
dsRNA virus
protein binds dsRNA to antagonize interferon |
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Definition
HIV
direct fusion by enveloped, some receptor mediated
inhibits PKR
code for own replicase/transcriptase
-RNA to -DNA via reverse transcriptase |
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Term
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Definition
vesicular stomatitis VSV, rabies
VSV enveloped virus helical
-RNA
receptor mediated by enveloped
- strand RNA
VSV: DI particles from deletions panhandles or hairpins |
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sindbis, semiliki, forest virus, SFV
+ strand virus, make - strand by translating polyprotein |
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Definition
rhinovirus
polio-naked capsid cubic
protease cleaves PKR
narrow host range isn't infectious to mice in capsid but is without it Mab against polio
+RNA
and can inhibit PKR |
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Term
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Definition
annealing of + and - strands
reovirus dsRNA
overlapping genes in dsDNA
uncapped 5' ends |
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Term
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Definition
endosome: TLR3 binds dsRNA
cytoplasm: RNA helicase RIG-1 binds dsRNA and ssRNA 5'PPP while MDA-% recognizes long dsRNA |
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Term
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Definition
Mx protein induced
2'5'oligo A synthetase induced
RNA-activated PKR induced |
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Term
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Definition
| activates RNase L degrades RNA, protein synthesis inhibited --> cell dies |
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Term
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Definition
| prevents initiation of translation-->cell death |
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Term
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Definition
retain 5' and 3' BP
smaller take less time to replicate
interfere for proteins |
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