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Virology
Mosby Comprehensive Review
39
Veterinary Medicine
Not Applicable
02/16/2010

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Term
adjuvant
Definition
substances added to a vaccine commonly mineral oil, alum, bacterial fractions, some sugars, or combinations of these that increase the antigencity and therefore the degree of teh immune response
Term
adsorb
Definition
to attract and retain other material on the surface
Term
altered self
Definition
any change in the molecular configuration of ones cells that may result in attack by the immune system. This state may be a result of viral invasion of cells, cancer, radiation, or poisoning
Term
autolysis
Definition
rupture or death of a cell
Term
capsid
Definition
shell of a protein that protects the nucleic acid of a virus
Term
DNA
Definition
short for deoxyribonucleic acid, the physic basis for the genetic code.
Term
genome
Definition
entire genetic complement of an organism. In animals it involves DNA and RNA, but in viruses it is one or the other.
Term
inactivated
Definition
rendered inert or nonfunctional by exposure to heat of sufficient temperature and duration
Term
latent
Definition
quiescent state awaiting later reactivation, which may occur years later. In the case of latent viruses, they insert their DNA into the host cell DNA to be replicated together. Frequently stress is implicated in teh viruses resurgence and resultant disease state.
Term
lysin
Definition
agent that ruptures and therefore kills host cells
Term
lysogenic cycle
Definition
ability to cause lysis or produce lysins, ability to exit a host cell by rupturing that cell causing death.
Term
naked virus
Definition
a virus that does not have a lipid membrane
Term
nucleic acid core
Definition
molecule of DNA or RNA, either of which can be double or single stranded the term is used synonymously with viral genome.
Term
obligate intracellular parasite
Definition
a parasite that lives within a host cell.
Term
oncogenesis
Definition
production of tumors
Term
Parasite
Definition
one organism that survives at the detriment of another
Term
portal of entry
Definition
pathway by which a pathogenic agent gains entry to the body
Term
prion
Definition
proteinaceaous infections particle, the smallest known microorganism. Laboratory tests indicate that although this microorganism does not possess any nucleic acid, it consists of protein and is capable of producing desease..
Term
portal of entry
Definition
pathway by which a pathogenic agent gains entry to the body
Term
recombinant
Definition
produced through DNA technology using the pathogens genome to create the anigenicity and immune response. because the virus is not intact there is no risk of disease to the patient
Term
refractory
Definition
resistant capable of withstanding adverse conditions and surviving
Term
reverse transcriptase RNA
Definition
enzyme of RNA viruses that catalyzes the transcription of RNA to DNA, which is then incorporated into a genome of the host cell self recognized by the immune system as ones own molecular configuration and therefore tollerated
Term
RNA
Definition
one form of nucleic acid, of which there are 3 forms. ribosomal,messenger, and transfer. The codes for the assemble of proteins. Some viruses such as the retroviruses possess only RNA in there genome, but because they possess a reverse transcriptase enzyme, they can reverse code for DNA
Term
subclinical
Definition
used to describe the early stages or a ery mild form of a disease
Term
titer
Definition
strength per volume of a volumetric test solution
Term
T lymphocyte
Definition
Lymphocytes that do not produce antibody, rather they primarily act to destroy altered self in the body due to viral infection or neoplastic transformation
Term
tolerance
Definition
state of being tolerated by the immune system and therefor not attacked. in health this occurs in ones own body only, if it is conveyed to microorganisims, it will result in an immunodeficiency.
Term
viremia
Definition
stage of some infections where the virus enters the blood and spreads throughout the body.
Term
viricidal
Definition
term meaning virus killer, frequently used to describe disinfectant chemicals with this capacity
Term
viron
Definition
intact functional virus particle, capable of infecting a host cell
Term
Bovine Leukemia
Definition
Retrovius, no vaccine
Term
Spongiform encephalopathy
Definition
Prion, no vaccine
Term
Bovine Viral Diarrhea
Definition
Pestivirus, Vaccine available
Term
Bovine Calf scours complex
Definition
Rotavirus and coronavirus, vaccine available
Term
Bovine Foot and mouth
Definition
picornavirus, short term vaccine available
Term
Bovine Infections rhinotracheities
Definition
Herpesvirus, vaccine available
Term
Bovine Parainfluenza-3
Definition
Paramyxovirus Vaccine available
Term
Bovine Respiratory syncytial virus
Definition
Paramyxovirus, No vaccine
Term
Bovine Vesicular stomatitis
Definition
Vesiculovirus, no vaccine
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