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Virology-Arteroviridae
virus
16
Veterinary Medicine
Undergraduate 3
05/31/2012

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Term
arterovirus infects...
Definition
...horses = Equine Viral Arteritis
Term
genotype of arterovirues=
Definition
+ssRNA

and nesting mRNAs
Term
does arterovirus have an ENV?
Definition
yes
Term
peplomers of arterovirus =
Definition
small
Term
capsid of arterovirus =
Definition
icosahedral
Term
sporadic outbreaks of equine viral arteritis are common when....
Definition
...groups of horses assembled, eg at war
Term
prevelance of equine viral arteritis
Definition
rare (but dz is widespread)
Term
most outbreaks of equine viral arteritis seen where?
Definition
on stud farms
Term
infection of equine viral arteritis transmitted ...
Definition
...by sexual transmission or by resp route
Term
equine viral arteritis replicates in...
Definition
...monocytes and epi cells
Term
signs of equine viral arteritis =
Definition
most the time assymptomatic

at v high blood titres of the virus:
1. fever (>41C)
2. rhinitis
3. conjunctivitis & XS lacrimation - pink eye
4. leukopenia (decr WBCs)
5. damage endothelium of bvs = urticaria (itchy rash with swelling) - vascular reaction of upper dermis
6. extensive oedema of ventral abdo and hindlegs
Term
equine viral arteritis infection in preg mare =
Definition
virus crosses placenta = abortion
Term
equine viral arteritis infection of stallion =
Definition
can become persistantly infected and virus shed in semen
Term
immunity against equine viral arteritis associated with...
Definition
...neutralising Abs
Term
vacc of equine viral arteritis =
Definition
1. live attenuated vacc but NOT safe for use in mares - protects animal developing symptoms but not from being infected

2. killed vacc with an adjuvant available for preg mares, but req boosting.
Term
dx of equine viral arteritis confirmed by...
Definition
...
virus isolation
detection of virus by RT-PCR (highly sensitive test used to detect RNA viruses)
serology
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