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administration of multiple drugs concurrently in smaller quantities than would be required if each were given alone, to produce sedation, tranquilization, muscle relaxation, analgesia, or a variety of other effects needed for a particular patient. Maximizes benefits, minimizes adverse effects, and gives the anesthetist the ability to produce anesthesia with the degree of CNS depression, muscle relaxation, analgesia, and immoblization appropriate for the patient and procedure |
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regional anesthesia produced by injection of a local anesthetic or analgesic into the epidural space surrounding the spinal cord |
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a reversible state of unconsciousness, immobility, muscle relaxation, and loss of sensation throughout the entire body produced by administration of one or more anesthetic agents |
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a sleeplike state from which the patient can be aroused with sufficient stimulation |
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a loss of sensation in a small area of the body produced by administration of a local anesthetic agent in proximity to the area of interest |
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a drug induced sleep from which the patient is not easily aroused and that is most often associated with the administration of narcotics |
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painful or physically harmful |
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a specific stage of general anesthesia in which there is a sufficient degree of analgesia and muscle relaxation to allow surgery to be performed without pain or movement |
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TI; a ratio of the toxic to the theraputic dose of a drug, used to measure relative safety. A drug with a wide theraputic index (much more of the drug is required to intoxicate a patint than is required to treat it) is relatively safer than a drug with a narrow theraputic index (one for which the toxic and theraputic doses are similar). Most anesthetic agents have a very narrow theraputic index so the consequences of a calculation or adminstration error may be serious |
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A loss of sensation of a localized area produced by administration of a local anesthetic directly to a body surface or to a surgical or traumatic wound |
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a drug-induced state of calm in which the patient is reluctant to move and is aware of but unconcerned about its surroundings |
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drug-induced CNS depression and drowsiness that vary in intensity from light to deep |
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