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a drug that brings about a specific action by finding with the appropriate receptor |
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the extent to which the drug causes the intended affects the patient |
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expresses a relationship between a drug’s therapeutic and harmful effects |
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a group of specialized molecules on or in a cell the bond with the drug to produce an effect |
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a reason not to use a drug in a particular situation |
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the amount of time that must elapse between the end of drug therapy and the elimination of that drug from the patient’s tissues or products |
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2. Four sources of drugs used in veterinary medicine |
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- Animal products - plant materials - minerals - synthetic products |
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What are four components of a drug regimen? |
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The dose, the route of administration, the frequency of administration, and the duration of administration |
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. Discuss the conditions that must be met before a valid veterinarian client patient relationship can be shown to exist |
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• the veterinarian must assume responsibility for making clinical judgments in relation to the health of the animal • the veterinarian must have recently seen the animal and be acquainted with its care • the veterinarian must be available for follow-up care of the animal |
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Discuss the responsibilities of a veterinary technician in the administration of drug orders |
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carry out the veterinarian’s orders correctly, read the drug label three times, administer the correct dose by the correct route. Be aware of expected effects, potential adverse side effects to be able to monitor the patient |
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. Describe the sequence of events that a drug undergoes from administration to excretion |
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first absorbed or directly placed into the bloodstream • in the blood, the drug may bind with a plasma protein or may exist in a free state • circulating blood distributes the drug to the capillary level • drug leaves the circulation enters the interstitial fluid • interstitial fluid base to sell allows the drug to enter the cell or binder surface receptors • drug then exits the cell back into fluid, reenter circulation, transported to the liver for metabolism. • After metabolized, metabolite transported to the kidneys for excretion |
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List 11 possible routes for administering a drug to a patient |
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• oral - simple, many factors may influence rate of absorption, may not be appropriate if vomiting • sub Q-absorption may be slow, hypertonic solutions should not be given by this route • IM -faster absorption than sub Q, care not to inject into blood vessels • IV-immediate access to bloodstream, dilution of irritating drugs, may have toxic or allergic reaction • IP-maybe use for fluids some other solutions when other routes not available, slow absorption • IA seldom used, may produce seizures or death • IC - primarily for emergency drugs or euthanasia • Intramedullary-small animals, damaged veins • inhalation, drugs to the respiratory system • topical-skin or mucous membranes, may be facilitated by carrier substances • intradermal-primarily for allergy testing, diagnosing tuberculosis |
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list some of the factors that influence drug absorption |
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• method of absorption • pH of the drug and ionization status • absorptive surface area • blood supply to area • drug solubility • dosage form • status of G.I. tract • interactions with other drugs |
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most biotransformation of drugs occurs in |
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Most drug excretion occurs via which of the following? |
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drugs usually produce their effects by combining with specific cellular |
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The drug named as chosen by the manufacturer and that is the exclusive property of that company is called__ |
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What are six items that must be included on a drug label |
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• drug names (generic and trade) • drug concentration and quantity • name and address of manufacturer • controlled substance status • manufactures control Lot number • expiration date |
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. What are three government agencies that regulate the development approval and use of animal health products? |
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why do so many veterinary clinics dispense rather than prescribe most of the drugs they use? |
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What is the purpose of FARAD? |
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Resources concerning avoidance of drug residues in animals |
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Extra label veterinary drug use was made legal by what act of Congress? |
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animal medicinal drug use clarification act – AMDUCA |
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diluting or combining of existing drugs |
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what are the potential dangers of residues in animal products? |
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Allergic reactions/neoplasia in people, antibiotic resistant strains of bacteria |
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List three classes of drug interactions |
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• pharmacodynamic • pharmacokinetic • pharmaceutics |
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Drug interaction can be anticipated when two drugs are given that are both metabolized by the__ |
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an ethical product is one sold only through veterinarians as a policy of the manufacturer rather than by FDA requirements |
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. Once a drug has been biotransformed, it is called a__ |
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An (A)__is a reason to use the drug |
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The diagnostic method of choosing a drug is based on all the following except__. Practical experience assessment of the patient obtaining a history performing laboratory tests |
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Extra label use means__. A. sold over-the-counter B. Using a drug in a way not specified by the label C. Using the drug according to the empirical method D. Deciding how long the drug should be given. |
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Using a drug in a way not specified by the label |
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. All the following are true about the VCPR except: A. The veterinarian has seen and treated all the client’s pets except a dog for which the owner would like heartworm preventative. B. The veterinarian has assumed responsibility for making clinical judgments about the health of the animal and the need for treatment and the client has agreed to file the veterinarians instructions C. Veterinarian has sufficient knowledge of the animal tissue diagnosis veterinarian must have recently seen the animal must be acquitted with its husbandry D. The veterinarian must be available for follow-up evaluation of the patient |
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A. The veterinarian has seen and treated all the client’s pets except a dog for which the owner would like heartworm preventative. |
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.__Is the complex sequence of events that occurs after a drug is administered to a patient. |
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what the drug does to the body. |
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__Is the body’s ability to change the drug chemically from the form in which it was administered into a form that can be eliminated from the body. |
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Metabolism (biotransformation |
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The__of the drug represents the degree to which a drug produces its desired response in a patient. |
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An adverse drug reaction is always life-threatening |
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All the following agencies regulate animal health products except__. A. FDA B. EPA C. AVMA D. USDA |
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