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VETT 213 Pharmacology & Medical Theraputics III
Wk 1 General Pharmacology
38
Veterinary Medicine
Not Applicable
01/20/2013

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Cards

Term
a. Agonist
Definition
a drug that brings about a specific action by finding with the appropriate receptor
Term
b. Efficacy
Definition
the extent to which the drug causes the intended affects the patient
Term
c. therapeutic index
Definition
expresses a relationship between a drug’s therapeutic and harmful effects
Term
d. receptor
Definition
a group of specialized molecules on or in a cell the bond with the drug to produce an effect
Term
e. contraindication
Definition
a reason not to use a drug in a particular situation
Term
f. withdrawal time
Definition
the amount of time that must elapse between the end of drug therapy and the elimination of that drug from the patient’s tissues or products
Term
2. Four sources of drugs used in veterinary medicine
Definition
- Animal products
- plant materials
- minerals
- synthetic products
Term
What are four components of a drug regimen?
Definition
The dose, the route of administration, the frequency of administration, and the duration of administration
Term
. Discuss the conditions that must be met before a valid
veterinarian client patient relationship can be shown to exist
Definition
• the veterinarian must assume responsibility for making clinical judgments in relation to the health of the animal
• the veterinarian must have recently seen the animal and be acquainted with its care
• the veterinarian must be available for follow-up care of the animal
Term
Discuss the responsibilities of a veterinary technician in the administration of drug orders
Definition
carry out the veterinarian’s orders correctly, read the drug label three times, administer the correct dose by the correct route. Be aware of expected effects, potential adverse side effects to be able to monitor the patient
Term
. Describe the sequence of events that a drug undergoes from administration to excretion
Definition
first absorbed or directly placed into the bloodstream
• in the blood, the drug may bind with a plasma protein or may exist in a free state
• circulating blood distributes the drug to the capillary level
• drug leaves the circulation enters the interstitial fluid
• interstitial fluid base to sell allows the drug to enter the cell or binder surface receptors
• drug then exits the cell back into fluid, reenter circulation, transported to the liver for metabolism.
• After metabolized, metabolite transported to the kidneys for excretion
Term
List 11 possible routes for administering a drug to a patient
Definition
• oral - simple, many factors may influence rate of absorption, may not be appropriate if vomiting
• sub Q-absorption may be slow, hypertonic solutions should not be given by this route
• IM -faster absorption than sub Q, care not to inject into blood vessels
• IV-immediate access to bloodstream, dilution of irritating drugs, may have toxic or allergic reaction
• IP-maybe use for fluids some other solutions when other routes not available, slow absorption
• IA seldom used, may produce seizures or death
• IC - primarily for emergency drugs or euthanasia
• Intramedullary-small animals, damaged veins
• inhalation, drugs to the respiratory system
• topical-skin or mucous membranes, may be facilitated by carrier substances
• intradermal-primarily for allergy testing, diagnosing tuberculosis
Term
list some of the factors that influence drug absorption
Definition
• method of absorption
• pH of the drug and ionization status
• absorptive surface area
• blood supply to area
• drug solubility
• dosage form
• status of G.I. tract
• interactions with other drugs
Term
most biotransformation of drugs occurs in
Definition
liver
Term
Most drug excretion occurs via which of the following?
Definition
Kidneys
Term
drugs usually produce their effects by combining with specific cellular
Definition
receptors
Term
The drug named as chosen by the manufacturer and that is the exclusive property of that company is called__
Definition
proprietary or trade
Term
What are six items that must be included on a drug label
Definition
• drug names (generic and trade)
• drug concentration and quantity
• name and address of manufacturer
• controlled substance status
• manufactures control Lot number
• expiration date
Term
. What are three government agencies that regulate the development approval and use of animal health products?
Definition
FDA, EPA, USDA
Term
why do so many veterinary clinics dispense rather than prescribe most of the drugs they use?
Definition
profit
Term
What is the purpose of FARAD?
Definition
Resources concerning avoidance of drug residues in animals
Term
Extra label veterinary drug use was made legal by what act of Congress?
Definition
animal medicinal drug use clarification act – AMDUCA
Term
Define compounding
Definition
diluting or combining of existing drugs
Term
what are the potential dangers of residues in animal products?
Definition
Allergic reactions/neoplasia in people, antibiotic resistant strains of bacteria
Term
List three classes of drug interactions
Definition
• pharmacodynamic
• pharmacokinetic
• pharmaceutics
Term
Drug interaction can be anticipated when two drugs are given that are both metabolized by the__
Definition
liver
Term
Ethical product
Definition
an ethical product is one sold only through veterinarians as a policy of the manufacturer rather than by FDA requirements
Term
. Once a drug has been biotransformed, it is called a__
Definition
metabolite
Term
An (A)__is a reason to use the drug
Definition
Indication
Term
The diagnostic method of choosing a drug is based on all the following except__.
Practical experience
assessment of the patient
obtaining a history
performing laboratory tests
Definition
Practical experience
Term
Extra label use means__.
A. sold over-the-counter
B. Using a drug in a way not specified by the label
C. Using the drug according to the empirical method
D. Deciding how long the drug should be given.
Definition
Using a drug in a way not specified by the label
Term
. All the following are true about the VCPR except:
A. The veterinarian has seen and treated all the client’s pets except a dog for which the owner would like heartworm preventative.
B. The veterinarian has assumed responsibility for making clinical judgments about the health of the animal and the need for treatment and the client has agreed to file the veterinarians instructions
C. Veterinarian has sufficient knowledge of the animal tissue diagnosis veterinarian must have recently seen the animal must be acquitted with its husbandry
D. The veterinarian must be available for follow-up evaluation of the patient
Definition
A. The veterinarian has seen and treated all the client’s pets except a dog for which the owner would like heartworm preventative.
Term
.__Is the complex sequence of events that occurs after a drug is administered to a patient.
Definition
Pharmacokinetics
Term
define pharmacodynamic
Definition
what the drug does to the body.
Term
__Is the body’s ability to change the drug chemically from the form in which it was administered into a form that can be eliminated from the body.
Definition
Metabolism (biotransformation
Term
The__of the drug represents the degree to which a drug produces its desired response in a patient.
Definition
Efficacy
Term
An adverse drug reaction is always life-threatening
Definition
False
Term
All the following agencies regulate animal health products except__.
A. FDA
B. EPA
C. AVMA
D. USDA
Definition
AVMA
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