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Seven classifications of Taxonomy |
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Kingdom, phylum, class, order, family, genus, species |
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order of rodents, largest order, located worldwide, hindgut fermenters, hind limbs > fore limbs, large eyes, prominant ears, most build nests, like to gnaw and chew, have a Harderian gland behind the eye, rarely vomit, have a simple stomach with large cecum and colon, herbivorous, copophagic, high metabolic rate, no sweat glands and unable to pant, open rooted incisors (some have open rooted molars as well), no premolars or canines |
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The gland located behind the eye of rodents which secretes lubricants to the eye |
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Largest rodent in the world |
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Largest rodent in North America |
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Signs of overheating in Rabbits |
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Salivation and licking forelegs to cool off, cannot pant or sweat, prostrating self, and seizures |
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teeth that grow continuously throughout the life of the animal |
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The gap between the incisors and molars of rodents (have not canines or premolars) |
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The distance between the anus and the genital papilla, primary way of sexing rodents, males typically have 2x the distance of females |
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"domestic mouse", most common animal in research, ~3 yr lifespan, weigh ~ 30g |
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strains that have parent x offspring or brother x sister for at least 20 generations, they are homozygous and have nearly identical DNA |
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Hairless, have no thymus, used in tumor research |
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Recently bred mice abort if exposed to a strange male |
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females housed together with no male go into anestrous and syncronize estrus |
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Blood collection sites (Mice) |
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Definition
Orbital sinus, cephalic, lateral tail vein, cardiac puncture |
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SQ, Intraperitoneal (IP) AVOID IM |
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Using a dosing needle to force feed an animal. The dosing needle inserts down the throat and into the stomach. |
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Clinical Signs of Pneumonia |
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Definition
Teeth chattering, dyspnea, weight loss, conjunctivitis |
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Virus: Sendai virus - most common Bacterial: Mycoplasma, Bordetella, Pasturella, Klebsiella |
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Bacteria causing hepatitis and inflammatory bowel disease |
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Caused by Clostridium piliforme, seen in young and stressed animals, signs are diarrhea, dehydration, anorexia, sudden death, common in pet shop animals, post mortem shows milliary pale foci in liver, seen in Mice, Gerbils, Rabbits |
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Seen with dermatitis, bite wounds, conjunctivitis, pharyngitis, and cervical lymphadenitis |
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caused by coronavirus, highly contagious, common in research colonies, does not persist, stop breeding for 8-15 weeks until it resolves |
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Epizootic Diarrhea of Infant Mice (EDIM) |
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Definition
Rotovirus, occurs in young animals 1-3 wks old, causes stunted growth and soft yellow feces |
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Lymphocytic Choriomeningitis |
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Definition
flu-like symptoms, zoonotic |
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4 Bacterial Diseases in Mice |
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Definition
Pneumonia, Helicobacter, Tyzzer's Disease, Staph/Strep |
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Definition
Sendai Virus - m.c. cause of Pneumonia Mouse Hepatitis Virus (Coronavirus) EDIM (Rotovirus) Lymphocytic Choriomeningitis Ectromelia (pox virus) Parvovirus Encephalomycarditis virus Hantavirus (zoonotic, wild mice, SW US) |
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Dominant mouse chews the hair on other mice, see rough coat and skin lesions, perpetrator is unaffected |
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Most common squamous cell tumor in mice, most are malignant, seen in older mice |
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