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Vet 1010: Lab Animal Medicine
Mouse, Rat, Hamster, Gerbil, Rabbit, Guinea Pig, Chinchilla, and Frog
222
Veterinary Medicine
Undergraduate 1
01/28/2011

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Cards

Term
Name Four of the Genetic Characteristics
Definition
Outbred, Transgenic, Inbred, Congenic
Term
What is Outbred?
Definition
Strains are the result of random mating to achieve genetic variations.
Term
What is Inbred?
Definition
result of inter-family matings for a minimum of 20 consecutive generations
Term
What is Congenic?
Definition
Genetically differ at one particular locus on the gene.
Term
What is a lab mouse used for?
Definition
research
Term
what is a lab mouse defined by?
Definition
ecological and genetic characteristics
Term
What studies/research are lab mice used for?
Definition
toxicology, biomedical
Term
What represents the diversity of the human population?
Definition
Outbred
Term
Outbred, Transgenic, Inbred, Congenic is all characteristics of?
Definition
Genetic
Term
What are Inbred Genetic lab mice used for?
Definition
Transplantation research
Term
Name an example of an Inbred Strains
Definition
BALB/c strain
Term
Name an example of Outbred Strains.
Definition
CD-1
Term
What is transgenic?
Definition
result of micro injection of DNA into mouse eggs for the production of very specific disease models.
Term
what are transgenic used for?
Definition
cancer research
Term
Name the 5 ecological charateristics.
Definition
Axenic, Gnotobiotic, Specific Pathogen Free, Barier sustained, Conventional
Term
What is Axenic?
Definition
Germ Free
Term
Axenic animals are derived from ........
Definition
Hysterectomy due to contamination factors
Term
where are axenic lab mice kept?
Definition
maintained in a germ free isolation housing system.
Term
What is Gnotobiotic
Definition
Germ free mice that have been introduced to one or more known nonpathogenic microorganism
Term
Where are Gnotobiotic housed in?
Definition
isolators or barrier units
Term
What does SPF stand for?
Definition
Specific Pathogen Free
Term
What is Specific Pathogen Free?
Definition
free from specific pathogenic organisms
Term
What does VAF stand for?
Definition
Viral Antibody Free
Term
What is conventional?
Definition
Housed with no special precautions; wild
Term
Conventional's are typically SPF/VAF in origin.
Definition
True
Term
What is Sentry?
Definition
used to ensure that the animals maintain their expected health status.
Term
What housing is used for sentry?
Definition
barrier-sustained and conventional
Term
What is the lifespan of the mouse?
Definition
2 years
Term
What is a mouse prone to?
Definition
Neoplasia and trauma
Term
What is neoplasia?
Definition
new growth; mass
Term
What is located in the housing of a mouse?
Definition
Hardwood shavings or chips
Term
Why can's softwood chips be in housing of a mouse?
Definition
potentially cause liver damage and epithelial damage
Term
When does a female mouse reach sexual maturity?
Definition
50 days
Term
What is the scientific name for mouse?
Definition
Mus musculus
Term
What is the scientific name for a rat?
Definition
rattus norvegicus
Term
Name 7 of the rat breeds.
Definition
Fancy, Albino, American Blue, Black&White hooded, Siamese, Male Dumbo, and Zucker.
Term
What is the most common house rat?
Definition
Black & White Hodded
Term
What is the lifespan of a rat?
Definition
up to 3 years
Term
When does a rat reach sexual maturity at?
Definition
1.5 to 2 months
Term
how long is the gestation of a rat?
Definition
22 days
Term
What are rats susceptible to?
Definition
neoplasia esp. in mammary gland tumors
Term
What health problems do rats have?
Definition
mycoplasma respiratory infections and susceptible to neoplasia in mammory gland tumors
Term
What are harderian glands?
Definition
gland located in the corner of a rats eyes that secretes porphyrin
Term
What animal has harderian glands?
Definition
rat
Term
Where are harderian glands located?
Definition
in the corner of the eyes
Term
[image]
Definition
ALBINO RAT
Term
[image]
Definition

MALE

DUMBO

RAT

Term
[image]
Definition
FANCY RAT
Term
[image]
Definition
BLACK & WHITE HOODED RAT
Term
[image]
Definition
AMERICAN BLUE RAT
Term
[image]
Definition
SIAMESE RAT
Term
[image]
Definition
ZUCKER RAT
Term
What is the scientific name for a Syrian Hamster?
Definition
Mesocricetus auratus
Term
What is a Syrian Hamster used for?
Definition
as a pet and research model
Term
What types of models does Syrian Hamsters with Inbred strains make?
Definition
epilepsy, muscular dystophy, and heart failure
Term
What does Syrian Hamsters have that make them useful in studies?
Definition
unigue pouch used to transport food, but for research on tumor induction, tissue & organ transplant, and microcirculation
Term
What is life expectancy of a Syrian Hamster?
Definition
18-24 months
Term
Why does a Syrian Hamsters urine have a milky appearence?
Definition
high pH of 8 and it's full of crystals
Term
Syrian Hamsters are nocturnal.
Definition
True
Term
Does Syrian Hamsters choose different areas of their cage or the same area for food storage, nesting, defecation, and unrination?
Definition
Different
Term
Do Syrian Hamsters burrow, hoard food, escape, and are naturally social?
Definition
FALSE-all but the social is true. They are best kept separate.
Term
Are males or female Syrian Hamsters bigger?
Definition
Females-they are also stronger and more aggressive
Term
Name some characteristics of female Syrian Hamsters.
Definition
larger, stronger, and more aggressive
Term
What are Flank Glands?
Definition
sebaceous glands are used to mark territory.
Term
What are omnivores?
Definition
can supplement diet with fresh fruits and vegtables
Term
How do you restrain a Syrian Hamster?
Definition
grasp by loose skin over the neck and shoulder using whole hand
Term
Syrian Hamsters are very ____ sleepers; cab be _________ if awakened and startled.
Definition
deep; aggressive
Term
What are the ways to handle a Syrian Hamster?
Definition
Gently scoop up in the palm of the hand/container or to use the Smile restrain technique
Term
How long is the gestation period for hamsters?
Definition
16 days
Term
How long do you leave the female and her litter alone for?
Definition
At LEAST 7 days postpartum
Term
How long is the estrus cycle of the hamster?
Definition
4 days
Term
What is fecundity?
Definition
fertile
Term
During what season does hamster exhibit a normal decrease in fecundity and mortality in litters will increase?
Definition
Winter
Term
Where on a hamster can you take a sample from?
Definition
cephalic, tarsal, lingual, or jugular
Term
Where is lingual?
Definition
tongue
Term
Which venipuncture sites on a hamster requires sedation?
Definition
Lingual and jugular
Term
What is an important thing to do before sedating a hamster?
Definition
calculate amount to collect
Term
Name some health conditions hamsters have.
Definition
Wet Tail, Tyzzer's disease, Salmonella spp., Lymphocytic Choriomeningitis virus, Antibiotic Sensitivity, Pneumonia, Endoparasites, and ectoparasites.
Term
What are the zoonotic conditions hamsters get?
Definition
Salmonella and Lymphocytic
Term
Name some Hamster breeds.
Definition
Syrian/Golden Hamster, Brown & White Syrian, Sable/Short Haired, Teddy Bear, and Albino.
Term
What is the scientific name for a Mongolian Gerbil?
Definition
Meriones Unguiculatus
Term
What is the lifespan of a Gerbil?
Definition
3 years
Term
What animals have a harderian gland?
Definition
Syrian Hamster and the Mongolian Gerbil.
Term
Mongolian Gerbils need ____ water and therefore urinate _____ amounts.
Definition
Low small
Term
What temperatures can Mongolian gerbils tolerate?
Definition
32-92 F
Term
What animal has better temperature regulation?
Definition
Mongolian Gerbil
Term
What gerbil breed is the main lab breed?
Definition
Mongolian
Term
Are Mongolian Gerbils herbivorous, omnivorous, or granivorous?
Definition
Herbivorous and granivorous
Term
Does the Male or Female Mongolian Gerbil Hoard?
Definition
Both-Femal moreso
Term
Are mongolian Gerbils active at night or day?
Definition
Day
Term
what are Mongolian Gerbils susceptible to?
Definition
epileptic type seizures after excitement, stress, and sudden noises. recovery spontaneously
Term
What can cause an epileptic type seizure in a Mongolian Gerbil?
Definition
excitement, stress, and sudden noise
Term
What are Monoglian gerbils used for in research?
Definition
Mainly radiation, epilepsy, infectious disease, endocrinology, and lipid metabolism.
Term
Why is the Mongolian Gerbil so useful in radiation studies?
Definition
more resistant to radiation
Term
There are ____ variations with a ____ range of sizes for Mongolian gerbils.
Definition
Many/wide
Term
Mongolian gerbils are what type of dwellers?
Definition
Desert
Term
Name some characteristics for the Mongolian Gerbil.
Definition
Gentle, friendly, curious, day active
Term
What is the gestation period for Mongolian Gerbils?
Definition
25 days
Term
How long is the estrus cycle in a Mongolian Gerbil?
Definition
4-6 days
Term
Mongolian Gerbils are _________ with the other sex.
Definition
Monogamous
Term
If a male Mongolian Gerbil is seperated after the female gives birth he should be returned within how long?
Definition
2 weeks
Term
Why would a male Mongolian Gerbil be removed from a female that just gave birth?
Definition
to avoid postpartum mating.
Term
How do you handle a Mongolian Gerbil for examination?
Definition
grip the base of the tail with one hand and the loose skin around the neck and shoulder with the other
Term
How do you handle a gerbil?
Definition
scoop up with both hands and be sure they don't jump out
Term
why should you never grab a gerbil or lizard by the tail?
Definition
It will deglove.
Term
what does the Mongolian Gerbil not tolerate?
Definition
being on their backs.
Term
What are some health conditions of the Mongolian Gerbil?
Definition
Tyzzer's Disease, Nasal Dermatitis, Salmonella, Malocclusion, Tumors
Term
What are some of the problems associated with limited access to water with Mongolian Gerbil?
Definition
lower fertility rates, decreased body weights, and higher mortality
Term
What is another
Definition
Term
What is another words for Nasal Dermatitis?
Definition
Sore Nose
Term
What usually causes Nasal dermatitis or "Sore Nose"?
Definition
Stess and anxiety by product
Term
What does Intraperitoneal mean?
Definition
into abdominal Cavity (IP)
Term
Where can you get a sampling from in the Mongolian Gerbil?
Definition
SQ, IM, IV
Term
What is the scientific name for Rabbit?
Definition
Oryctolagus Cuniculus
Term
How are Rabbit breed divided by?
Definition
Size, shape, color, and variations.
Term
What are the three divisions of rabbits?
Definition
Large, Medium, and Small.
Term
What is Propophageic?
Definition
animals that eat their poop
Term
What is the most common SPF rabbit produced commercially for research?
Definition
New Zealand White
Term
What is the most common SPF rabbit produced commercially for research?
Definition
New Zealand White
Term
Name some characteristics of rabbits.
Definition
docile, alert, gregarious burrowers, crepuscular
Term
Aggressive or Nervous rabbits may do what?
Definition
stomp their hind feet and spray urine
Term
What noise can rabbits make?
Definition
high pitched scream
Term
Are rabbits herbivorous, omnivorous, or carnivorous?
Definition
herbivorous
Term
What does crepuscular mean?
Definition
active at twilight
Term
What is the normal temperature of a rabbit?
Definition
101.3-104.
Term
What is the life expectancy of a rabbit?
Definition
5-6 years
Term
rabbits reguire a _____ _____ diet that will decrease hairballs.
Definition
High fiber
Term
What serves as the rabbit's heat regulatory organ?
Definition
Highly vascularized ears
Term
What teeth do rabbits have?
Definition
a pair of incisors in the top, a smaller pair (peg teeth) behind them
Term
decribe rabbit urine.
Definition
thick, cloudy, contains crystalline material
Term
Decribe the daytime feces.
Definition
hard, dark green, round.
Term
How long after eating does these type of feces produce?
Definition
4 hours
Term
Describe Nightime feces.
Definition
moist, strong in odor, bright green, mucus covered.
Term
Do rabbits eat nighttime or daytime feces?
Definition
Nighttime
Term
Why does eating nighttime feces benefit rabbits?
Definition
increase the digestibility of protein and maintain adequate nutrition and intestinal flora.
Term
Rabbits can easily get ____ _____ if not supported properly.
Definition
spinal fractures
Term
How do you pick up a rabbit?
Definition
grasp loose skin over neck area and support the hind limbs with the other.
Term
Rabbits can be picked up by the ears. (t/f)
Definition
FALSE
Term
What should you do before handling a rabbit?
Definition
approach slowly and speak softly to avoid startling
Term
When placing a rabbit
Definition
Term
When placing a rabbit into the cage what should you do?
Definition
Place hind end first
Term
What should you watch when handling a rabbit?
Definition
powerful bites, charging and scratching
Term
Can rabbits be placed on their backs?
Definition
yes- in the handlers lap carefully
Term
What is the gestation period for rabbits?
Definition
28-31 days
Term
What animal does not have an estrous cycle?
Definition
Rabbit
Term
During parturition what should you not do?
Definition
do not disturb the doe
Term
What do you call a female rabbit?
Definition
doe
Term
What do you call baby rabbits?
Definition
kits
Term
t/f : Rabbits are induced ovulators.
Definition
True
Term
Where do you get a blood draw from?
Definition
Saphenous or ear vein
Term
you can do a SQ, IM, or IV on a rabbit. t/F?
Definition
True
Term
What are some health conditions of the rabbit?
Definition
pasteurellosis, trichobezoars, coccidiosis, dermatitis/alopecia
Term
what is trichobezoars?
Definition
hairballs
Term
What is the scientific name for a guinea pig?
Definition
Cavia porcellus (CAVY)
Term
Name some Guinea Pig breeds.
Definition
Silkie, Teddie/Rex, Texal, Crested, coronet, Hairless, Peruvian, Short Haired, English, Dutch Colored Abyssinian
Term
What is hypsodontic teeth?
Definition
Teeth that keep growing
Term
What will Guinea Pigs do at unexpected movements or sounds?
Definition
Term
What is the scientific name for a Chinchilla?
Definition
Chinchilla Langier
Term
What is Scurvy?
Definition
Lack of Vitamin C
Term
What is Malocclusions?
Definition
slobbers
Term
What is cervical lymphadenitis?
Definition
Lumps
Term
What are some health conditions of Rabbits?
Definition
scurvy, malocclusions, cervical lymphadenitis, bacterial pneumonia, salmonella, anesthesia complications, and dermatitis
Term
t/f: Accessing veins for injections or bleeding requires sedation or anesthesia in Guinea Pigs.
Definition
True
Term
What are the most common Guinea Pig breeds for pets?
Definition
Peruvian, Abyssinian, and English
Term
Name characteristics of the guinea pig.
Definition
nervous but tame and easily handled, poor jumping/climbing, may freeze/stampede at unexpected noise/movement
Term
what is the l-gluconolactone oxidase enzyme
Definition
involved in the synthese of ascorbic acid from glucose
Term
What does Guinea pigs have to have added to their diet?
Definition
Vitamin C
Term
Commercially prepared lab guinea pig diets contain a form of vitamin c that is stable for how long?
Definition
90 days
Term
What type of feeders are guinea pigs?
Definition
monogastric herbivores
Term
what is monogastric?
Definition
one stomache
Term
How do you feed a guinea pig?
Definition
free choice hay w/some fresh vegtables and fruits as treats.
Term
What do guinea pigs respond poorly to?
Definition
stress and antibiotic therapy as well as diet change
Term
What are guinea pigs used for in research?
Definition
genetics, anaphylaxis, microbiology, immunology, nutritution, and audiology
Term
what is anaphylaxis?
Definition
allergy reaction
Term
What uses does guinea pig serum have?
Definition
diagnostic test for infectious dieseases
Term
What are chinchilla babies called?
Definition
kits
Term
When is the vaginal closure membrane open?
Definition
estrus and parturition
Term
How many pairs of mammory glands does Chinchilla's have?
Definition
3
Term
What is the lifespan of a Chinchilla?
Definition
10 years
Term
What is the Chinchilla's normal temp range?
Definition
100.4-102.2 f
Term
At what temperature is a Chinchilla most comfortable?
Definition
under 79 f
Term
How many toes does a Chinchilla have on a foot?
Definition
4
Term
Name some characteristics of a Chinchilla.
Definition
virtually odorless, love to jump/climb, coprophagic
Term
What animal has more fur per square inch then any other?
Definition
Chinchilla
Term
What do Chinchilla's need/require?
Definition
frequent dust baths, proper commercial diet and free choice hay, fresh fruit & vegies as treats.
Term
How do you handle a hand raised Chinchilla?
Definition
they will come to you usually
Term
How do you pick up a Chinchilla?
Definition
Scruff neck and support rump
Term
what is fur slip?
Definition
loss of a large patch of fur
Term
what type of handling can cause fur slip?
Definition
rough or inexperienced
Term
Chinchilla's come from the same family as the _______.
Definition
guinea pigs
Term
What is a Chinchilla's history?
Definition
once hunted for fur; very rare if not extinct in the wild
Term
What type of research are chinchilla's used for?
Definition
Hearing
Term
What are some health concerns with Chinchilla's?
Definition
constipation, fur ring, paraphimosis, alopecia, malocclusion, choke & bloat
Term
What is alopecia caused by?
Definition
can be ringworm
Term
what is paraphimosis?
Definition
caused by a ring of fur around the penis that eventually stops the penis from retracting into the prepuce
Term
How often should male chinchilla's be checked for paraphimosis?
Definition
Weekly
Term
What is the scientific name for the African Clawed Frog?
Definition
Xenopus laevis
Term
What is the African Clawed Frog used in research for?
Definition
embryonic development studies, eggs used for diseases involving ion channels
Term
What are signs of choke?
Definition
retching, drooling, dyspnea, anorexia
Term
What are signs of bloat?
Definition
lie on their side with swollen abdomens
Term
how do you help an animal with bloat?
Definition
by decompressing the abdomen by passing a gastric tube or inserting a needle/trocar
Term
How can you give Chinchillas medication?
Definition
Orally, SQ IM IP IV
Term
What is the best way to give a Chinchilla a pill if they don't chew it up alone?
Definition
in raisins or bread
Term
t/f. Chinchilla's can be very sensitive to injections.
Definition
True
Term
In African Clawed Frogs, who is bigger male or female?
Definition
Females
Term
What is amplexing?
Definition
mating
Term
what do male african clawed frogs have for amplexing?
Definition
slimmer bodies and legs w/ black nuptial pads on their forearms for grasping female
Term
What appears to induce reproduction of the african clawed frog?
Definition
environmental factors
Term
t/f? Any manipulation that takes over a few minutes and could potentially be painful should be done under anesthesia.
Definition
True
Term
How do you give an african clawed frog anethesia?
Definition
MS222 (tricaine methanseulphonate is buffed with sodium bicarbonate. place the frog into the solution.
Term
How do you handle the african clawed frog?
Definition
observe in tank first. use good quality net
Term
what does Xenopus lack?
Definition
tongue
Term
what is the lifespan of the african clawed frog?
Definition
15 years
Term
How do the african clawed frogs breathe?
Definition
Larvae-breathe with external gills. Adults breathe through lungs, skin, and buccopharyngeal cavity
Term
t/f African Clawed frogs can not regenerate lost limbs.
Definition
False-they do rapidly
Term
How can you tell african clawed frogs apart?
Definition
due to their unique colors, patterns-you can use photography-it's like our fingerprints
Term
how does an african clawed frog feel?
Definition
mucoid and slippery-this is a protective layer or mucus
Term
Where does the african clawed frog live?
Definition
totally aquatic
Term
Are african clawed frogs carnivorous, herbivorous, or omnivorous?
Definition
carnivorous: small pieces of organ meat (heart /liver) commercial frog brittle
Term
What is Ectotherms:
Definition
unable to generate enough metabolic heat to raise their body temps above the ambient level of the environment
Term
what are characteristics of the african clawed frog?
Definition
secretive and ectotherms
Term
What are some health concerns with the african clawed frog?
Definition
red leg(bacterial infection) parasitic infections, fungal infections, dropsy or bloat, susceptible to chemicals in water, susceptible to stress=disease very hardy
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