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vector bourne disease
ONU med micro r-anderson
24
Microbiology
Undergraduate 2
12/11/2011

Additional Microbiology Flashcards

 


 

Cards

Term
malaria causative agent
Definition
plasmodium falciparum
Term
malaria eitiology
Definition
eukaryotic
protozoan
sporozoan
Term
malaria reservoir
Definition
human-mosquito-human cylce
Term
malaria transmission
Definition
biological vector - female anopheles mosquito
parenteral route
Term
malaria clinical
Definition
cyclic fevers, anemia, shivering, pain in joints, headache, vomiting, convulsions, coma, death
Term
malaria pathogenesis
Definition
entry: parenteral route form mosquito
attach: hepatocytes then erythrocytes
avoid: intracellular, antigenic shifts
damage: capillary damage, anemia, clotting
exit: mosquito takes blood back
Term
malaria diagnosis
Definition
microscopic analysis of blood
cells contain plasmodium stages
Term
malaria treatment
Definition
chloroquine
atovaquone/proguanil
quanine and other drugs
Term
malaria prevention
Definition
no vaccine
control vector
public - spraying, remove water sources
personal - DEET insect repellent, netting, avoid dusk
Term
lyme disease causative agent
Definition
Borrelia burgdorferi
Term
lyme etiology
Definition
eubacterial pathogen
Gm -
spirochete
axial filaments
unique genome
Term
lyme reservoir
Definition
small mammals (white-footed mouse) and deer
Term
lyme transmission
Definition
vector-bourne
Ixodes tick (deer tick)
requires 1-2 days of feeding to transmit pathogen
Term
lyme clinical signs
Definition
multisystem
expanding target-shaped rash
flu like symptoms
arthritis
CNS - seizures, coma, death
Term
lyme diagnosis
Definition
difficult by clinical signs - mistaken for other things
ELISA, western immunoblot test
Term
lyme treatment
Definition
3-4 weeks of doxycycline or amoxicillin
cefuroxime or erythromycin for contraindicaitons
Term
lyme prevention
Definition
avoid tick bits
control deer populations
reduce tick populations near residential areas
Term
west nile virus etiology
Definition
flavivirus
ssRNA (+)
icosahedral capsid
enveloped
Term
west nile reservoir
Definition
infected birds
Term
west nile transmission
Definition
parenteral route from infected Culex mosquito
rare: blood transfusions
Term
west nile clinical
Definition
3-14 day incubation
most: fever, lymphadenopathy, headache, abdominal pain, vomiting, rash, anorexia, eye problems
rare: meningoencephalitis
Term
west nile treatment
Definition
supportive
some ICU care or ventilaiton
Term
diagnosis
Definition
antigen test done by CDC
Term
west nile prevention
Definition
habitat elimination
DEET
community wide spraying
dont be out at dusk
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