Shared Flashcard Set

Details

valvular heart disease
Step 1 Review
55
Biology
Graduate
12/30/2007

Additional Biology Flashcards

 


 

Cards

Term
Where is the mitral valve located
Definition
between the left atrium and left ventrile
Term
What does mitral stenosis cause
Definition

1.  Abnormal emptying of the LA into the LV during diastole

3.  Pressure gradient is created 

Term
Mitral stenosis causes _____ murmur after _____
Definition
diastolic & S2
Term
What is the number one cause of Mitral Stenosis
Definition
Rheumatic Heart disease
Term
In mitral stenosis an increase pressure leads to _____
Definition
Enlargement of the atrium
Term
Name the 3 hemodynamic that go wrong in Mitral stenosis
Definition

1.  Obstruction of blood flow

2.  Increase blood acceleration

3.  Reduced CO 

Term
What happens to Stroke Volume in mitral stenosis
Definition
Increased due ejecting blood at a higher pressure
Term
Describe the pathophysiology for Left atrial hypertension in Mitral stenosis
Definition
Blood goes back into the Left atrium due to no valve and causes Plumonary hypertension
Term
What are the effects of Left atrial HTN
Definition

1.  Dyspnea

2.  Pulmonary edema

3.  Hemoptysis

4.  RH failure 

Term
Name the two types of Pulmonary hypertension
Definition
Passive and reactive
Term
What happens in Passive Pulmonary hypertension
Definition

1.  Increasee in pumonary artery pressure to preserve blood flow

2.  Hyperplasia of theintima in smaller arterial vessels 

Term
What happens in reactive pulmonary HTN
Definition

1.  Increase arterial pressure impedes blood flow into the pulmonary bed & reduces capillary hydrostatic Pressure

2.  RV pumps against increased resistance that leads to hypertrophy 

Term
How do you manage Mitral Stenosis
Definition

1.  Beta blockers to reduce effect of obstruction

2.  Relieve congestion w/ Diuretics

 

Term
Mitral Regurgitation causes a ______ murmur
Definition
Systolic
Term
What happens to preload in the PV loop in mitral reguritation
Definition
Shifts to the right due to increased preload
Term
What are the 3 causes of Mitral reguritation
Definition

1.  leaflet abnormalities

2.  Subvalvular apparatus

3.  Annular Dilatation

 

Term
Describe the effect of Acute MR on the left atrium and ventricle
Definition

Left atrium

Increased LA vol lead to increased LA pressure to prevent reguritation, this pressure is transmitted bdack to the pulmonary cirulation resulting in pulmonary congestion & edema

 

Left ventricle

Increasing sarcomere stretch to accommodate increase in volume, this results in increase LV volume and decrease AL 

Term
What happens in chronic compensated MR
Definition
left ventricle gets bigger
Term
Describe the effects of Chronic compensated MR on the left atrium
Definition
the left atrium increases in size & compliance to lessen the effects of reguritation on pulmonary circulation this leads to near normal LA & pulmonary pressure but low CO
Term
Describe the effects of Chronic compensated MR on the left ventricle
Definition
Hypertrophy leads to increase in diastolic volume at low P and increase CO to near normal levels
Term
What happens in Chronic decompensated MR
Definition
Left ventricle can no longer push blood foward and LA cannot strech so you get decline in CO and signs of HF
Term
How would a heart w/ MR look like on CXR
Definition
bat wing
Term
Aortic Stenosis causes a ______ murmur
Definition
systolic
Term
What are the causes of Aortic Stenosis
Definition

1.  Congenital 

2.  Acquired 

-Rheumatic

-Degenerative 

Term
What's the pathphysiology in Aortic Stenosis
Definition

1.  Obstruction of blood flow from LV to aorta

2.  Increased LV P

3.  Mitral reguritation 

Term
Describe the LV compensation in aortic stenosis
Definition

1.  Decreased compliance (LA hypertrophy)

2.  Angina

3.  Decrease coronary blood flow

 

Term
What are the clinical manifestations of Aortic Stenosis
Definition

1.  Angina

2.  Syncope during exercise

3.  CHF 

Term
What's the management for a person w/ Aortic Stenosis
Definition

1.  Hypertensives

2.  Surgical

Term
Aortic Regurgitation occurs during _____
Definition
Diastole
Term
Name the Valve causes of Aortic Regurgitation
Definition

1.  Congenital bicuspid valve

2.  Endocarditis

3.  Degenerative aortic valve

4.  Syphilis 

Term
What are the causes of Aortic Root disease for Aortic Regurgitation
Definition

1.  Degenerative aortic dilation

2.  Cystic medial necrosis

3.  Aortic dissection 

Term
Describe the pathophysiology of Acute Aortic regurgitation
Definition
Left Ventricle Pressure rises transmitting P to the LA & pulmonary circulation this leads to dyspnea, pulmonary edemia & decrease CO
Term
what's the pathophysiology was Chronic Aortic Regurgitation
Definition
LV undergoes compensatory adaptation increasing LV end diastolic Pressure and LV hypertrophy
Term
what's the jones criteria for rheumatic heart disease
Definition

FEVERSS

1.  Fever

2.  Erythema marginatum (macular skin rash)

3.  Valvular damage

4.  ESR increase

5.  Red hot joints (polyarthritis)

6.  Subcutaneous nodules

7.  St. Vitus dance (chorea-involuntary choreiform movements of the extremities) 

Term
Rhumatic fever occurs ____ weeks after strep throat
Definition
2-4 weeks
Term
Rheumatic fever is the cross reacting of antibodies against ______ __ _____
Definition
Surface M protein
Term
How does the mitral looks if affected in Rheumatic heart disease
Definition
Fish mouth or buttonhole
Term
Aschoff bodies are seen in
Definition
Rheumatic heart disease
Term
Describe an Ashcoff body
Definition
Occurs in the myocardial interstitum, has a owl eye appearance.  Granuloma w/ giant cells
Term
Describe an Anitschkow cell.  Where do you see them?
Definition

Fibrinoid necrosis surrounded by large histocyes.

 

You see them in Rheumatic heart disease 

Term
What are the classic signs of Endocarditis
Definition

FROM JANE

1.  Fever

2.  Roths spots

3.  Osler's nodes

4.  Murmur

5.  Janeway lesions

6.  Anemia

7.  Nail-bed hemorrhage

8.  Emboli 

Term
Which two organisms are associated w/ Acute Endocarditis
Definition

1.  S. aureus (50%)

2.  S. pyrogenes (35%)

Term
Acute Endocarditis affects which valve in IV drug users
Definition
Tricuspid
Term
Acute endocarditis affects previous _______ valves
Definition
normal
Term
For acute endocarditis vegetations can form from _______ or ______ or they can ______ the value
Definition

1.  Myocardial abscesses

2.  Septic emboli

 3.  Destroy

Term
Subactue bacterial endocarditis affects perviously _______ heart
Definition
abnormal
Term
The main organism in Ssbactue bacterial endocarditis is
Definition
S. viridans
Term
What kind of onset does subactue bacterial endocarditis have
Definition

insidious

1.  Positive blood cultures

2.  Fatigue

3.  Low-grade fever w/out chills

4.  Splinter hemorrhage 

Term
What are the Predisposing factors in subacute bacterial endocarditis
Definition

Prosthetics

Pre-existing valves 

Term
What are some complications of Bacterial endocarditis
Definition

1.  Chordae rupture

2.  Glomerulonephritis

3.  Suppurative pericarditis

4.  Emboli 

Term
In bacterial endocarditis, which valve is most frequently involved
Definition
Mitral
Term
Libman-Sacks endocarditis is called by ____
Definition
SLE
Term
Libman sacks endocarditis affects which sides of the valves
Definition
both sides
Term
Which valve is most commonly affected in Nonbacterial thrombic endocarditis
Definition
Mitral Valve
Term
Do Libman sacks endocarditis emboli
Definition
NO
Supporting users have an ad free experience!