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UWORLD STEP 3
1
67
Medical
Post-Graduate
11/03/2015

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Cards

Term
What are the confidence intervals associated with the ranges 1, 2 and 3 standard deviations from the mean?
Definition
68%, 95%, 99.7%
Term
Who gets a right ventricular mi
Definition
30-50% of pts with an inferior MI
Term
complications of right ventricular MI, tx?
Definition
cardiogenic shock after administration of nitrates esp. tx with IVF to inc preload
Term
signs of vertibrobasilar insuff
Definition
vertigo, dysarthria, diplopia, numbness
Term
causes of vertebrobasillar insuff
Definition
emboli/thrombi or arterial dissection
Term
when do ppl get labyrinthitis and what are the signs
Definition
s/p viral infection, trauma or a med

vertigo, tinnitus, nausea
Term
rules for warfarin use in pregnancy
Definition
use LMWH instead during first Tri and in the predelivery period
Term
herpes destationis
Definition
pruritis on abdo, followed by pruritic vesicles and papules surrounding umbilicus, likely autoimmune in etiology NOT viral
Term
tx herpes gestationis
Definition
triamcinolone
Term
hook like osteophytes seen on XR in painful joints
Definition
hemochromatosis
Term
what does cutaneous Cryptococcus look like
Definition
umbilicated papules with hemorrhagic crusts
Term
test for cutaneous cryptococcus
Definition
biopsy shows multinuc giant cells, histiocytes, lymphocytes, plasma cells etc
Term
stain for cutaneous cryptococcus
Definition
periodic acid Schiff
gomori silver nitrate
Term
ttriad of tuberous sclerosis
Definition
ash leaf spots, sz, hamartomas
Term
most common cause of death in tuberous sclerosis
Definition
sz d/o
Term
test for tuberus sclerosis
Definition
always do EEG first, then check for TSC-1 gene
Term
imaging issue with subarachnoid hemorrhage, sol'n?
Definition
SAH will only be seen on non-contrast CT if done 6-12 hours within sx onset. if after that, you have to do an LP
Term
treatment for erectile dysfunction in DM
Definition
PDE inhibitor like sildenfinil
Term
treatment for erectile dysfunction in DM
Definition
PDE inhibitor like sildenfinil
Term
problem with treating erectile dyfunction and BPH
Definition
PDE inhibitors when given at same time as alpha blockers like terazosin will cause hypotension. so you have to give them 4 hours apart
Term
EKG changes with further increasing potassium
Definition
peaked T, no P wave, sine wave wide complex EKG
Term
when do you treat hyperK with EKG changes, how?
Definition
when there are changes beyond peaked T waves.

Calcium gluconate first then either glucagon+insulin or Beta blocker
Term
when do you treat hyperK with EKG changes, how?
Definition
when there are changes beyond peaked T waves.

Calcium gluconate first then either glucagon+insulin or Beta blocker
Term
diuretics and potassium
Definition
most cause hypokalemia, except for Potassium sparing diuretics that can cause hypokalemia (spironolactone, traimterein, amiloride)
Term
what other drugs cause hyperkalemia (besides the potassium sparing diuretics)
Definition
nsaids
Term
eval pre stimulant adhd tx
Definition
cardiac hx and PE, height weight vitals
Term
next step if no improvement on methylphenidate for adhd
Definition
atomoxetine
Term
which CCB make worse edema
Definition
dihydrooyridine (amlo, nifedipine)
Term
medicare A, B, C, D
Definition
A= inpt/hospice/skilled nursing
B= outpt/obs
C= private insurance advantage
D= Rx
Term
drugs that cause lupus rxn
Definition
hydralazine, minocycline, TNFalpha block (etenercept/inflixamib), procainamide
Term
sx of lupus rxn
Definition
pleural effusion, arthritis, night sweat, fatigue
Term
test for lupus drug rxn
Definition
ana, anti histone Ab
Term
manage bleeding in subchorionic hemorrhage in preggo
Definition
no tx, just rpt u/s in one week
Term
when do you do TIPS in pt with esophageal varicies?
Definition
s/p 2 failed endoscopy with banding procedure
Term
when/what meds do you use in esophageal varicies
Definition
octreotide can be used while you are doing endoscopy or tips (acute)

non selective BB used in prevention
Term
causes of bloody nipple discharge
Definition
papilloma
invasive intraductal carcinoma
ALWYS do mammo
Term
what lab valued determine mortality in end stage liver failure in the MELD equation. What is MELD equation used to determine?
Definition
bili, INR, Cr

when do do Tips procedure
Term
what lab valued determine mortality in end stage liver failure in the MELD equation. What is MELD equation used to determine?
Definition
bili, INR, Cr

when do do Tips procedure
Term
alt meds that cause inc bleeding
Definition
ginseng, ginko, ginger, black cohash, saw palmetto
Term
dx test for ankylosing spondylithosis
Definition
sacroiliac xr
Term
monitor pts with ankylos spondy
Definition
rpt xr and esr
Term
systemic symptoms of ankylosing spondy
Definition
uveitis, aortic regurg, pulm fib, iga nephron, colon ulcers,
Term
unclear u/s in suspected cholecystectomy. what do you do next
Definition
hida scan
Term
when may you see Mallory Weiss tear in non-alcoholic? what direction is the tear?
Definition
someone with hiatal hernia
vertical
Term
biggest side effect of TURP
Definition
retrograde ejaculation
Term
treatment of Cryptococcus meningitis
Definition
amphotericin B & flucystine IV
then if improvement you can switch to fluconazole
Term
transverse vaginal septum vs imperforate hymen
Definition
both will have hematoculpos (suprapubic mass 2/2 blood filled uterus) but imperforate hymen will also have a bulging mass between the labia, transverse septum is too high to see on genital exam
Term
desmoid tumor features
Definition
deep seated mass often in trunk or proximal limb +- pain
Term
desmoid tumors and cancer
Definition
desmoid tumors more common in familial adenomatosis polyposis.

desmoid tumors have a high rate of recourrance though they aren't cancers themselves
Term
best way to evaluate a desmoid tumor
Definition
ct/mri early on to determine extensiveness of lesion
Term
features of oropharyngeal dysphagia vs esophageal dysphagea
Definition
oropharyngeal: cough, drool, difficulty with initiating swallow, may have ear pain

esophageal: delayed sensation of food sticking in chest
Term
sub categories of oropharyngeal dysphagia
Definition
neuromuscular oropharyngeal dysphagia: solids and liquids at onset

mechanical obstruction oropharyngeal dysphagia: solids at onset then liquids
Term
initial imaging in either oropharyngeal dysphagia vs esophageal dysphagia
Definition
nasopharngeal laryngoscopy
vs egd for esophageal
Term
common complication of Cryptococcus neoformans meningitis and tx
Definition
increased ICP bc the capsule of the fungus causes a spinal fluid outflow obstruction which can be treated with therapeutic LP
Term
squamous cell carcinoma of esophagus vs adeno risk factors
Definition
squam: etoh + cigs
adeno: gerd
Term
Addisons' disease pathogensis
Definition
adrenal insufficiency and a secondary INCREASE in ACTH
Term
addisons disease sx
Definition
weight loss, brown spots, abd pain, weakness

LOW sodium, HIGH potassium
HYPERCHLOREMIC metabolic ACIDOSIS
Term
what test do you do if suspicious for addisons disease
Definition
give 250micrograms of cosyntropin (ACTH like hormone) then measure cortisol and acth after

-if after giving cosyntropin the ACTH is high and the cortisol is low then they have primary adrenal insuff
Term
med tx for chronic prostatitis
Definition
levo/cipro
Bactrim
these penetrate prostate better
Term
pancoast tumor progression of cns sx
Definition
invasion of the paravertebral chain causes horners syndrome with pupil asymmetry

invastion of the spinal cord (emergency) causes asymettrical lower extremity dtr
Term
meds that cause c diff
what does c diff look like on scope
Definition
clinda and cipro

yellow raised plaques
Term
features of acute chest syndrome in sickle cell disease
Definition
1. new pulmo infiltrate on cxr
2. fever
3. hypoxemia, CP, SOB
Term
most common cause of acute chest syndrome

tx?
Definition
bact infection
CTX and azithromycin and Pain control
Term
first line management of PEA
Definition
CPR and epi
Term
cause of acute hemolytic transfusion rxn

symptoms?

management?
Definition
ABO incompatibility

flank pain, fever, chills, HgBuria

stop blood, give IVF instead
Term
def of hypoglycemia
Definition
less than 60
Term
negative c diff tox A&B but still high susp for c diff....next step
Definition
sigmoidoscopy
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