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USMLE2 Saturday
Questions I got wrong sat
59
Medical
Professional
09/22/2012

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Term
Morton Neuroma
Definition
Mechanically induced degernerative neuropathy seen in runners. Pain between 3rd/4th toes, reproducible w/ a clicking sensation while palpating and squeezing metatarsals. Treat with shoes inserts.
Term
Symtomatic bradycardia?
Definition
Atropine
Term
Most common cause endometritis postpartum?
Definition
Polymicrobial. Treat with Clindamycin and gentamicin.
Term
PID treatment
Definition
Ceftriaxone and azithromycin
Term
What vitamin should be given to people with measles?
Definition
Vitamin A
Term
Newborn at 2 days presents with rash. Non-toxic neonate with erythematous papules/vesicles surrounded by erythema. +Eosinophils.
Definition
Erythema Toxicum. Self-limited. Looks like a really mild chicken pox.
Term
Turner's syndrome at risk for what bone problems?
Definition
Osteoporosis due to low estrogen levels
Term
Low back pain worse in the morning improves during the day.
Definition
Ankylosing spondylitis. Seronegative spondyloarthropathy. Men <40. Xray changes in sacroiliac joint (sacroiliitis). +ESR, = rheumatoid
Term
Pseudomonas treatment in pulm. infection of CF pt
Definition
Piperacillin and tobramycin. (antipsuedomonal penicillin w/ aminoglycoside)
Term
SVT EKG signs and treatment
Definition
Narrow QRS, regular, no P waves. Give adenosine.
Term
Bug and treatment for intubation associated pneumonia
Definition
Psuedomonas. Cefepime or piperacillin-tazobactam
Term
Actinic keratosis
Definition
Sandpaper like. erythematous papules w/ central scale.
Term
Seborrheic keratoses
Definition
Elderly. Deeply pigmented or flesh colored lesions with velvety or greasy surface
Term
Elderly with bone pain, renal failure, hypercalcemia
Definition
MM until proven otherwise. Bence Jones proteins
Term
1) Calcium Oxalate stones
2) Calcium phosphate stones
Definition
1) Most common. Give calcium citrate if <5mm
2) Sign of primary hyperparathyroidism and rta
Term
Telltale murmur of VSD
Definition
Pansystolic murmur loudest at the left lower sternal border.

May also have diastolic murmur at the apex
Term
Histoplasmosis test

Treatment?
Definition
Urine antigen

Itraconazole
Term
Squamous cell carcinoma diagnostic findings
Definition
Invasive cords of squamous cells with keratin pearls. Look on vermillion borer lower lip
Term
Pellegra (niacin deficiency) Sx
Definition
Three Ds: Diarrhea, dermatitis, dementia
Term
Lacunar infarcts
Definition
Usually don't produce both sensory and motor deficits.

Pure motor hemiparesis, pure sensory stroke, dysarthria, ataxic hemiparesis
Term
1st line for acute mania
Definition
Short term: Haloperidol

Long term: Lithium, lamotrigine, olanzapine, quetiapine
Term
Levodopa/carbidopa early side effects?
Definition
Hallucinations, dizziness, headache, agitation
Term
Alzheimer's vs. Pick's
Definition
Picks (frontotemporal) will have bhavioral and personality changes. Disinhibition.
Term
Lymphoblasts without peroxidase positive granules but PAS+ material. TdT positive immunostaning
Definition
ALL
Term
One week after penicillin use pt develops drug-induced reaction consisting of?:
Definition
Fever, urticarial rash, polyarthralgia, lymphadenopathy.
Term
1st trimerster syphillis infection who is allergic to penicilin
Definition
Desensitize. Can't give tetracycline, erythromycin doesn't cross placement. Cipro ineffective/ no use in pregnancy.
Term
Toxic megacolon
Definition
Can happen with UC, often first presentation. Need xray

3+ of: Fever >38
HR >120
Neutrophilic leukocytosis >10,500
Anemia

Plus volume depletion, altered sensorium, electrolytes, or hypotension
Term
Fragmented red blood cells, hemolytic anemia, thrombocytopenia in a patient with renal failure and neuro signs of HA/confusion
Definition
Idiopathic TTP-HUS. Accumulation of large vWf multimers. Do plasma exchange (plasmapheresis)
Term
Pericarditis in setting of renal failure.
Definition
Uremic pericarditis. Dialysis.
Term
Forward slip of vertebrae in preadolescent children. Back pain, neuro dysfunction, palpable step off.
Definition
Spondylolisthesis.
Term
Paget's disease serum Ca, serum P, alk phos, urinary hydroxyproline
Definition
Nl, nl, high, high
Term
Disseminated hisoplasmosis
Definition
Palatal ulcers, hepatosplenomegaly, pancytopenia
Term
Firm solitary lymph nodes. Older patient with smoking history. Non-tender.
Definition
Squamous cell carcinoma.
Term
How do you evaluate uric acid stones?
Definition
Radiolucent. Get CT or IVP. Needle shaped crystals.
Term
Angioedema is due to deficiency in what?
Definition
C1 esterase inhibiter wwhich causes increased C2b and bradykinin.
Term
25 y/o pt, Michael Weaver, can't get erection. 15lb weight loss. Right sided gynecomastia, small testes. Decreased TSH, t3, t4
Definition
Chronic liver disease causing hyperestrogenism.
Term
Breast biopsy showing foamy macrophages and fat globules. Mammogram shows 3x3cm spiculated mass, calcifications. US shows hypoechoic
Definition
Fat necrosis. Who cares, do nothing.
Term
Anemia, renal failure, hypercalcemia in elderly patient
Definition
Multiple myeloma. Serum immunoelectrophoresis before bone marrow biopsy.
Term
Marfan's features + MR + thromboembolic + downward disclocation of lens
Definition
Homocystinuria. Autosomal recessive, cystathionine synthase deficiency.

Treat with high doses vit B6 (pyridoxal phosphate)
Term
Phenylketonuria
Definition
Absence phenylalanine hydroxlase. Build up in phenylalanine.

MR, fair complex, blue eyes, eczema, musty body odor.
Term
Krabbe's disease
Definition
Spingolipidosis, deficiency in beta- galactosidase. No myelin!

MR, blindness, deaf, paralysis, peripheral moto and sensory neuropathy.
Term
Tay Sach's
Definition
Another sphingolipidosis, beta-hexosiminidase A.

MR, blind, cherry-red macula, weak, seizures.
Term
Fabry's disease
Definition
Sphingolipidosis, alpha-galactosidase deficiency.

Angiokeratomas, peripheral neuropathy, asymptomatic corneal dystrophy. Kedney, heart failure. Thromboembolic events.
Term
IgA nephropathy
Definition
Most common cause glomerulonephritis in adults.

Recurrent episodes gross hematuria, ~5 days after URI. Normal serum complement levels
Term
Post-strep glomerulonephritis
Definition
Average 10 days for pharyngitis, 21 for impetigo.

Low serum complement levels!
Term
Bite cells, RBC inclusions
Definition
G6PD w/ Heinz bodies.

X-linked recessive. Hemoglobin oxidizes and becomes heinz bodies. Denatured hgb interrupts membrane and causes hemolysis. Caused by drugs, inf, fava beans.
Term
Microcytic target cells.
Definition
B-thalassemia minor, asymptomatic
Term
Spherocytosis w/ increased reticulocytes
Definition
Hereditary spherocytosis. Spectrin disorder. RBC not deformable, gets trapped in fenestrations of spleen's red pulp.
Term
Low grade fever, sore throat, malaise, skin rash on palms/soles. Hx international travel. Superficial scaling and lymphadenopathy.
Definition
Spirochete, secondary syphilis.

3 doses benzathine penacillin given each week
Term
Maculopapular eruption wrist and ankles that spreads to trunk, extremities, palms, soles around day 5. HA, myalgias.
Definition
RMSF, rickettsial infection.

Doxycycline
Term
What medication is commonly associated with acquired angioedema
Definition
ACE-Is
Term
HIV pt with painless retinitis. Fluffy or granular rentinal lesions near retinal vessels w/hemorrhages. No conjunctivitis
Definition
CMV retinitis
Term
Acute retinal necrosis with pain, keratitis, uveitis, funduscopic findings of peripheral pale lesions and central retinal necrosis.
Definition
HSV retinitis. Can be severe, common cause of blindness.
Term
Bone conduction greater than air conduction
Definition
Conductive hearing loss. Likely otosclerosis.
Term
Palpitations. Mechanical valve. Schistocytes, increased LDH.
Definition
Microangiopathic hemolytic anemia. Look for schistocytes.
Term
Why does pancytopenia occur in patients with SLE
Definition
formation of autoantibodies against blood cells, type 2 hypersensitivity.
Term
BLurred vision, moderate pain, conjunctival injuection, constricted pupil.
Definition
Uveitis

Associated with HLA-B27 conditions (ankyndo)
Term
Swollen eyelid, edematous conjunctiva, exudates in anterior chamber
Definition
Postoperative endopthamitis. Within 6 weeks. Pain, decreased vision.
Term
Hypertriglyceridemia when levers are over 1000
Definition
Can lead to acute pancreatitis without gallstone or alcohol use. Look for eriptive xanthomas. Get fasting lipid profile
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