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Details

USMLE1 Endocrine Non-Pharm
N/A
6
Medical
Graduate
04/15/2011

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Cards

Term
Effects of insulin (6)
Definition
Increase glucose transport (GLUT4, skeletal muscle, adipose)
Increase glycogen synth and storage
Increase triglyceride synth and storage
Increase Na retention in kidneys
Increase protein synthesis in muscle
Increase cellular uptake of K and amino acids
Term
How does Mg regulate PTH?
Definition
Low Mg++ increases PTH, just like low Ca++.
Diarrhea, aminoglycosides, diuretics, alcohol.
Term
How do beta blockers treat hyperthyroidism?
Definition
Decrease adrenergic effects, also decrease peripheral conversion of T4 to T3.
Term
T3 functions? (4)
Definition
Brain maturation
Bone growth
Increase beta-receptors in heart - CO, HR, SV up
Increase basal metabolic rate via Na/K ATPase
Increase glycogenolysis, gluconeogenesis, lipolysis
Term
Aldosterone effect on serum concentrations?
Definition
High/normal Na (ANP "escape")
Low K
High HCO3
High/normal Cl
Term
Albright's hereditary osteodystrophy
Definition
AD, kidney unresponsive to PTH
Hypocalcemia, short 4th/5th digits, short stature
"pseudohypoparathyroidism"
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