Term
|
Definition
Direct cholinomimetic
activate bowels/bladder post surg
Cholinesterase resistant |
|
|
Term
|
Definition
Direct cholinomimetic (= ACh)
Glaucoma
Cholinesterase sensitive!
(only one besides ACh) |
|
|
Term
|
Definition
Direct cholinomimetic
Glaucoma
Stimulates sweat, saliva, tears (PILE on the fluids)
Cholinesterase resistant |
|
|
Term
|
Definition
Direct cholinomimetic
Challenge test for asthma
Cholinesterase resistant |
|
|
Term
|
Definition
Anticholinesterase
Postop/neurogenic ileus, myasthenia gravis, NMJ block reversal
No CNS penetration |
|
|
Term
|
Definition
Anticholinesterase
Myasthenia gravis, long acting
No CNS penetration |
|
|
Term
|
Definition
Anticholinesterase
Myasthenia gravis Dx, very short acting |
|
|
Term
|
Definition
Acetylcholinesterase inhibitor
Glaucoma, atropine overdose CNS entry
(phys for eyes - the one with CSF entry) |
|
|
Term
|
Definition
Anticholinesterase
Glaucoma |
|
|
Term
Parathion
Mech?
Use?
Antidote? |
|
Definition
| Irreversible AChE inhibitor (organophosphate) pesticide, toxin Antidote: atropine + pralidoxime |
|
|
Term
|
Definition
Irreversible AChE inhibitor (organophosphate)
pesticide, toxin
Antidote: atropine + pralidoxime |
|
|
Term
|
Definition
Muscarinic antagonist
causes mydriasis, cycloplegia |
|
|
Term
|
Definition
Muscarinic antagonist (= atropine)
causes mydriasis, cycloplegia |
|
|
Term
|
Definition
Muscarinic antagonist (= atropine) causes mydriasis, cycloplegia
"trop"icamide, a"trop"ine |
|
|
Term
|
Definition
Muscarinic antagonist
*Parkinson's disease |
|
|
Term
|
Definition
Muscarinic antagonist
motion sickness (patch) |
|
|
Term
|
Definition
Muscarinic antagonist
Asthma, COPD |
|
|
Term
|
Definition
Muscarinic antagonist
Reduce urgency, bladder spasm |
|
|
Term
|
Definition
Muscarinic antagonist
Reduce urgency, bladder spasm |
|
|
Term
|
Definition
Muscarinic antagonist
Peptic ulcers |
|
|
Term
|
Definition
Muscarinic antagonist
peptic ulcers |
|
|
Term
|
Definition
Nicotinic antagonist
ganglionic blocker - prevents vagal reflexes
causes orthostatic hypotension, blurred vision, constipation |
|
|
Term
|
Definition
Direct sympathomimetic
a1, a2, b1, b2 - low doses ~b1 selective
anaphylaxis, open angle glaucoma, asthma, hypoTN |
|
|
Term
|
Definition
Direct sypathomimetic
a1, a2, ~b1
hypoTN
causes decreased renal perfusion (less renin effect) |
|
|
Term
|
Definition
Direct sympathomimetic
b1, b2
AV block (rarely used) |
|
|
Term
|
Definition
Direct sympathomimetic
D1, D2, > b, > a, inotropic and chronotropic
increases renal perfusion, shock, CHF |
|
|
Term
|
Definition
Direct sympathomimetic
b1 > b2, inotropic (NOT chronotropic)
CHF, cardiac stress test |
|
|
Term
|
Definition
Direct sympathomimetic
a1 > a2
pupillary dilation, vasoconstriction, nasal decongestion |
|
|
Term
|
Definition
Direct sympathomimetic
b2 selective (~b1)
Acute asthma |
|
|
Term
|
Definition
Direct sympathomimetic
b2 selective (~b1)
acute asthma |
|
|
Term
|
Definition
Direct sympathomimetic b2 selective (~b1) long-term asthma tx
MAST
metaproterenol, albuterol, salmeterol, terbutline |
|
|
Term
|
Definition
Direct sympathomimetic b2 selective (~some b1) tocolytic
("but" like al"but"erol) |
|
|
Term
|
Definition
Direct sympathomimetic b2 selective (~b1)
tocolytic
(rito-DREAM, back to sleep for baby) |
|
|
Term
|
Definition
Indirect sympathetic agonist, releases stored catecholamines
Narcolepsy, obesity, ADD |
|
|
Term
|
Definition
Indirect sympathetic agonist, releases stored catecholamines
Nasal decongestion, urinary incontinence, hypotension |
|
|
Term
|
Definition
Indirect sympathetic agonist, uptake inhibitor
Vasoconstriction & local anesthesia |
|
|
Term
|
Definition
Indirect sympathetic antagonist
a2 agonist -> low central adrenergic outflow
Hypertension, especially with renal disease (no decrease in renal blood flow) |
|
|
Term
alpha-Methyldopa
Mech?
Use? |
|
Definition
Indirect sympathetic antagonist
a2 agonist -> low central adrenergic outflow
Hypertension, especially with renal disease (no decrease in renal blood flow) |
|
|
Term
Phenoxybenzamine
Mech?
Use? |
|
Definition
non-selective alpha-blocker, irreversible
pheochromocytomas |
|
|
Term
|
Definition
non-selective alpha-blocker, reversible
pheochromocytoma |
|
|
Term
|
Definition
alpha-1 selective blocker
HTN, urinary retention in BPH |
|
|
Term
|
Definition
alpha-1 selective blocker
HTN, urinary retention in BPH |
|
|
Term
|
Definition
alpha-1 selective blocker
HTN, urinary retention in BPH |
|
|
Term
|
Definition
alpha-2 selective alpha-blocker
Depression (TCA) |
|
|
Term
"-olols"
Mech?
Use?
Toxicity |
|
Definition
Beta-blockers
HTN (reduce CO, reduce renin secretion), Angina, MI, SVT (reduce AV conduction velocity), CHF, Glaucoma
Asthma/COPD exacerbation, bardycardia/AV block, impotence, sleep effects, decreased insulin release (caution in DM) |
|
|
Term
| Propranolol, timolol, nadolol, pindolol |
|
Definition
| Non-selective beta blockers |
|
|
Term
| acebutalol, betaxolol, esmolol, atenolol, metoprolol |
|
Definition
beta-1 selective beta blockers (good for comorbid asthma/COPD)
A BEAM of beta-1 selective blockers
ace-but = 1-b |
|
|
Term
|
Definition
| non-selective alpha- and beta-blockers |
|
|
Term
|
Definition
|
|
Term
|
Definition
Selective alpha-1 blocker
HTN, urinary retention in BPH |
|
|
