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USMLE 3 - Emergency Medicine
Question made from First Aid for USMLE step 3
66
Medical
Professional
08/21/2009

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Term
In ER toxicology the smell of bitter almonds on breath is suggestive for what?
Definition
cyanide
Term
Turpentine has what odor on breath?
Definition
violets
Term
Organophosphates (normally from ingestion of pesticides) give the breath what odor?
Definition
garlic
Term
Chloral hydrate yields what odor to breath?
Definition
pear
Term
The mneumonic COPS can be used to remember the causes for pupillary constriction. What are these categories?
Definition
Clonidine
Opiates
Pontine bleeds
Sedative-hypnotics
Term
What three broad classes of drugs/meds cause pupillary dilation?
Definition
Amphetamines
Anticholinergics
cocain
Term
Anticholinergics have what effect on bowel activity?
Definition
suppression
Term
Overdose on salicylates and organophosphates can both cause what in regards to skin?
Definition
diaphoresis
Term
Why might an O.D. on acetaminophen cause jaundice?
Definition
liver failure (mushroom poisoning may also cause jaundice)
Term
Arsenic and thallium, much like chemotherapeutic agents, have what effect on hair?
Definition
allopecia
Term
What are the symptoms of cholinergic overdose? (DUMBBELS)
Definition
Diarrhea
Urination
Miosis (pupillary constriction)
Bradycardia
Bronchospasm
Emesis
Lacrimation
Salivation
Term
What five categories of cholinergics does USMLE3 include?
Definition
organophosphates, pilocarpine, pyridostigmine, muscarine-containing mushrooms
Term
What type of drug/med overdose is described as "Hot as a stove, red as a beet, dry as a bone and mad as a hatter"? (fever, sking flushing, dry mucosa, pyshcosis, mydriasis, tachycardia, urinary retention)
Definition
anticholinergics (TCAs, atropine, scopolamine, antihistamines, Jimson weed)
Term
What are the descriptions of extrapyramidal signs?
Definition
Parkinsonian sx: tremor, torticollis, trismus (lock jaw), rigidity, oculogyric crisis, opisthotonos, dysphonia, dysphagia
Term
What bacteria may cause infection with a puncture wound through a rubber-soled shoe?
Definition
Pseudomonas
Term
What three agents commonly cause EPS?
Definition
phenothiazines, haloperidol, metoclopramide
Term
What is the first-line treatment for any toxic ingestion?
Definition
activate charcoal (1g/kg)
Term
Aside from activated charcoal, whole bowel irrigation can be used to help clean out the GI tract with what agent?
Definition
polyethylene glycol with electrolytes
Term
What emetic medication is used in the case of toxic ingections?
Definition
ipecac (30cc for adultes, 15cc for kids)
Term
What are the indications for ipecac use in toxic ingestion?
Definition
ingestion was recent (30-60 minutes), pt is awake and coperative, ingestion of substance was substantial/significant
Term
What are the contraindications for ipecac utilization?
Definition
AMS, reduce/absent gag reflex, agents which are easily aspirated
Term
What one criteria is added for the use of gastric lavage to those of ipecac utilization?
Definition
pt is able to be placed in L lateral decubitus position
Term
When pts are to be treated by alkalinization how is this done?
Definition
D5W with 2-3 ampules of NaHCO3
Term
Charcoal perfusion (siphoning off blood to be filtered by activated charcoal before re-infusing) is useful in what cases of toxic ingestion?
Definition
aminophylline, barbituates, carbamazepine, digoxin
Term
What medication is used in cases of acetominphen OD?
Definition
N-acetylcysteine
Term
What antidote is used for anticholinesterases and organophosphates?
Definition
atropine or pralidoxime
Term
What antidote is used for atropine?
Definition
physostigmine
Term
What antidote is used for benzo overdose?
Definition
flumazenil (antagonizes benzo receptors)
Term
What antidote is used for B-blocker overdose?
Definition
glucagon
Term
What are the three treatments for cyanide?
Definition
amyl nitrite pearls, sodium nitrite, sodium thiosulfate
Term
What treatment is used in digoxin toxicity?
Definition
digitalis fab fragments
Term
What medication is used to reverse heparin overdose?
Definition
protamine sulfate
Term
What chelator is used to treat iron toxicity?
Definition
deferoxamine
Term
Isoniazid is countered with what medication?
Definition
pyridoxine
Term
What medication is used to treat lead poisoning?
Definition
EDTA
Term
What medication is used to treat phenothiazines (atypical antipsychotics) overdose?
Definition
diphenhydramine
Term
What two interventions are taken for salicylate toxicity?
Definition
sodium bicarbonate and dialysis
Term
What treatment is used for TCA overdose?
Definition
sodium bicarbonate
Term
What two interventions are used to reverse the anticoagulation effects of warfarin?
Definition
vit K and fresh frozen plasma
Term
When does delerium tremens set in from alcohol withdrawl and what is its mortality?
Definition
2-7 days, 15-20%
Term
What vitamine should be given to withdrawing alcoholics before glucose?
Definition

thiamine

(B1)

Term
What are the symptoms of barbiturate withdrawl?
Definition
anxiety, seizures, delirium, tremor, cardiac/respiratory depression
Term
What medication is used to treat barbiturate overdose?
Definition
benzodiazepines
Term
What heart rate regulating drugs should be avoided in pts suffering from cocain withdrawl?
Definition
B-blockers
Term
What type of cranial fracture is assumed when a pt has Battle sign (hemorrhage/ecchymosis around mastoid process) or raccoon eyes?
Definition
basilar skull fracture
Term
What Glasgow coma score is indicative for intubation?
Definition
less than 8
Term
What emergent condition should be suspected in a pt with muffled heart sounds and JVD?
Definition
cardiac tamponade
Term
What type of EKG finding is seen in hypothermia between the QRS complex and T wave?
Definition
J wave (osborn wave)
Term
The front and back torso, if both entirely burned, would constitute what percentage of body area?
Definition
36%
Term
How can a 1st degree and 2nd degree burn be diferentiated by clinical appearance?
Definition
A 1st degree burn is red and painful, but without blisters
Term
What is the rough approximation for fluid resuscitation of burn victims?
Definition
4cc/kg/% BSA (1st half in 8 hours, and 2nd half in next 16)
Term
Which type of electrical burn (at same voltage) generates more tissue damage?
Definition
AC
Term
Which type of arrhythmia is more common with AC current?
Definition
VFib
Term
Which type of arrhytmia is more common with DC current?
Definition
asystole
Term
Burn victims exhibiting myoglobinuria should have what initial intervention?
Definition
IV fluids
Term
What is the antibiotic of choice for tetanus?
Definition
metronidazole
Term
For pts who are symptomatic for tetanus toxoid what intervention (aside from antibiotics) should be made?
Definition
tetanus immunoglobulin
Term
What are the three most likely culprits causing infection from a dog bite?
Definition
alpha-hemolytic strep (strep pneumonia and Viridans group), S. aureus, Pasteurella multocida
Term
What two antibiotics should be used in the case of dog bites?
Definition
amoxicillin/clavulanate or 1st-gen cephalosporin
Term
What bacterium is of primary concern in cat bites?
Definition
P. multocida (treat with amoxicillin/clavulanate)
Term
Which group of bacteria are the most commonly implicated in human bites?
Definition
Viridans streptococci
Term
What antibiotics should be used for human-bite wounds?
Definition
2nd or 3rd gen cephalos
dicloxacillin w/ PCN
amox/clav
Term
What is remarkable about the clinical examination of a corneal abrasion?
Definition
Pain out of proportion to exam (very painful)
Term
What is the tx for corneal abrasion?
Definition
topical solution antibiotics (gentamicin, sulfacetamide, bacitracin)
Term
What are the clinical differences between viral conjunctivitis vs bacterial?
Definition
Viral: usually bilaterally with watery dischage
bacterial: usually unilateral with purulent discharge and foreign body sensation
Term
What antibiotics should be used for staph or strep conjunctivitis?
Definition
10% sulfacetamide or aminglycoside
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