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urinary system
chapter on urinary
49
Aerospace Engineering
4th Grade
05/05/2014

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Term
juxtaglomerular apparatus
Definition
This region is made up of the thick ascending limb of the loop of Henle, the afferent and efferent arterioles.
Term
intercalated
Definition
These cells of the distal tubule and collecting duct are responsible for secreting hydrogen ions into the filtrate to help stabilize the body’s pH
Term
afferent arteriole
Definition
This blood vessel directs blood into the glomerulus.
Term
brush border
Definition
Cells of the proximal convoluted tubule are called ___ because of the microvilli in the luminal membrane.
Term
macula densa
Definition
These cells, highly regulated by hormones, help to fine tune the loss of solutes and water in the urine.
Term
JG Cells
Definition
These specialized cells in the afferent arteriole serve as baroreceptors for blood entering the glomerulus
Term
descending
Definition
The cells of the ___ limb of the loop of Henle are highly permeable to water, but not to solutes
Term
fenestrated
Definition
The glomerulus is made up of ___ capillaries
Term
ascending
Definition
The cells of the thick region of the __ limb of the loop of Henle are highly permeable to NaCl, but not to wate
Term
pedicles
Definition
Filtration slits in the outermost layer of the filtration membrane are formed by the ____ of the podocytes.
Term
macula densa
Definition
These cells serve as osmoreceptors in the thick ascending limb of the loop of Henle.
Term
efferent arteriole
Definition
Of the afferent and efferent arterioles, this one is smaller.
Term
dehydrated
Definition
Release of aldosterone and ADH are decreased when a person is ___.
Term
aldosterone
Definition
This steroid hormone, produced by the adrenal cortex, leads to increased sodium reabsorption (retention) and potassium secretion (loss in the urine).
Term
antidiertic hormone
Definition
This peptide hormone, secreted by the pituitary gland, leads to increased water reabsorption by the insertion of water channels or aquaporins in the cell membrane.
Term
300
Definition
Normal blood has an osmolarity of __ mOsm
Term
600
Definition
Normal urine has an osmolarity of __ mOsm.
Term
increases
Definition
With dehydration, urine osmolarity ____.
Term
vasoconstrict
Definition
As you might expect, sympathetic stimulation to the afferent arteriole will cause the vessel to ___
Term
secretion
Definition
Fine-tuning of the content of the filtrate is achieved by this movement of specific solutes from the peritubular capillaries into the nephron tubule.
Term
formed elements
Definition
Along with large proteins, these are prevented from passing through the glomerular filter, and therefore remain in the blood.
Term
decrease
Definition
One would expect to see a ___ in GFR if a person were dehydrated.
Term
capsular hydrostatic
Definition
This specific pressure, measuring around 15 mmHg, reduces the movement of fluid from the glomerular capillaries.
Term
hematuria
Definition
Damage to the glomerular filter may result in the presence of blood cells in the filtrate, a condition called:
Term
glomerular filtration rate
Definition
The total amount of filtrate formed by the kidneys per minute is:
Term
filtrate
Definition
The solution formed during filtration is called:
Term
charge
Definition
The glomerular filter prevents substances from passing through based on size and ___
Term
osmotic
Definition
This resistive pressure, measuring about 28 mmHg works to keep fluid in the glomerular capillaries
Term
reabsorption
Definition
Substances moving out of the filtrate in the nephron tubule and back into the blood in the peritubular capillaries is called:
Term
nitrogenous waste
Definition
Creatinine, urea and uric acid make up this component of the filtrate.
Term
capillary hydrostatic
Definition
This specific pressure, measuring about 60 mmHg, pushes fluid out of the glomerular capillaries.
Term
plasma
Definition
The concentration of solutes in the filtrate reflects the concentration of those solutes in the blood’s __.
Term
vasodilate
Definition
When blood pressure decreases during relaxation, the afferent arteriole will ___ in order to maintain a normal GFR
Term
angiotensin 2
Definition
This signal molecule, whose production is stimulated by renin, causes (a) vasoconstriction of the efferent arteriole, (b) increased glomerular hydrostatic pressure and (c) increased GFR.
Term
filtration
Definition
Fluid and solutes flow from the glomerulus into Bowman’s capsule during this renal process.
Term
luminal
Definition
Co-transporters that move sodium, potassium and 2 chloride ions together are found on the __ membrane of the thick ascending limb of the loop of Henle.
Term
Basolateral
Definition
The cells that make up the walls of the tubule have a membrane that faces the inside or lumen of the tubule and the other, which is in contact with the interstitial fluid. This outer membrane is called the ___ membrane.
Term
osmolarity gradient
Definition
Water is reabsorbed by following the ___ gradient
Term
transport maximum
Definition
Hyperglycemia indicates that the amount of glucose in the filtrate exceeds the ___ of the transporters
Term
reabsorption
Definition
Reclaiming of valued substances from the filtrate, and moving them back into the blood is called:
Term
concentration gradient
Definition
What drives the movement of sodium from the tubule into the PCT cells?
Term
chloride
Definition
This ion leaves the ascending limb of the loop and enters the interstitial fluid by following sodium ions
Term
increases
Definition
As the filtrate moves from the top to the bottom of the descending limb of the loop of Henle, the osmolarity ___.
Term
luminal
Definition
Co-transport of sodium with glucose and with hydrogen is seen on this membrane of the PCT.
Term
decreases
Definition
As the filtrate moves from the bottom to the top of the ascending limb of the loop of Henle, the osmolarity ___.
Term
basolateral
Definition
In the proximal convoluted tubule (PCT), sodium-potassium pumps are found on the ___ membrane.
Term
ascending
Definition
The transport that takes place in the __ limb of the loop of Henle drives the process studied in the countercurrent multiplier system
Term
transcellular
Definition
Most substances are moved through the ___ pathway during reabsorption.
Term
sodium
Definition
The movement of __ ions drives the movement of water out of the tubule during reabsorption
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