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juxtaglomerular apparatus |
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This region is made up of the thick ascending limb of the loop of Henle, the afferent and efferent arterioles. |
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These cells of the distal tubule and collecting duct are responsible for secreting hydrogen ions into the filtrate to help stabilize the body’s pH |
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This blood vessel directs blood into the glomerulus. |
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Cells of the proximal convoluted tubule are called ___ because of the microvilli in the luminal membrane. |
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These cells, highly regulated by hormones, help to fine tune the loss of solutes and water in the urine. |
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These specialized cells in the afferent arteriole serve as baroreceptors for blood entering the glomerulus |
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The cells of the ___ limb of the loop of Henle are highly permeable to water, but not to solutes |
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The glomerulus is made up of ___ capillaries |
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The cells of the thick region of the __ limb of the loop of Henle are highly permeable to NaCl, but not to wate |
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Filtration slits in the outermost layer of the filtration membrane are formed by the ____ of the podocytes. |
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These cells serve as osmoreceptors in the thick ascending limb of the loop of Henle. |
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Of the afferent and efferent arterioles, this one is smaller. |
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Release of aldosterone and ADH are decreased when a person is ___. |
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This steroid hormone, produced by the adrenal cortex, leads to increased sodium reabsorption (retention) and potassium secretion (loss in the urine). |
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This peptide hormone, secreted by the pituitary gland, leads to increased water reabsorption by the insertion of water channels or aquaporins in the cell membrane. |
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Normal blood has an osmolarity of __ mOsm |
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Normal urine has an osmolarity of __ mOsm. |
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With dehydration, urine osmolarity ____. |
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As you might expect, sympathetic stimulation to the afferent arteriole will cause the vessel to ___ |
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Fine-tuning of the content of the filtrate is achieved by this movement of specific solutes from the peritubular capillaries into the nephron tubule. |
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Along with large proteins, these are prevented from passing through the glomerular filter, and therefore remain in the blood. |
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One would expect to see a ___ in GFR if a person were dehydrated. |
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This specific pressure, measuring around 15 mmHg, reduces the movement of fluid from the glomerular capillaries. |
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Damage to the glomerular filter may result in the presence of blood cells in the filtrate, a condition called: |
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glomerular filtration rate |
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The total amount of filtrate formed by the kidneys per minute is: |
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The solution formed during filtration is called: |
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The glomerular filter prevents substances from passing through based on size and ___ |
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This resistive pressure, measuring about 28 mmHg works to keep fluid in the glomerular capillaries |
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Substances moving out of the filtrate in the nephron tubule and back into the blood in the peritubular capillaries is called: |
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Creatinine, urea and uric acid make up this component of the filtrate. |
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This specific pressure, measuring about 60 mmHg, pushes fluid out of the glomerular capillaries. |
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The concentration of solutes in the filtrate reflects the concentration of those solutes in the blood’s __. |
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When blood pressure decreases during relaxation, the afferent arteriole will ___ in order to maintain a normal GFR |
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This signal molecule, whose production is stimulated by renin, causes (a) vasoconstriction of the efferent arteriole, (b) increased glomerular hydrostatic pressure and (c) increased GFR. |
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Fluid and solutes flow from the glomerulus into Bowman’s capsule during this renal process. |
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Co-transporters that move sodium, potassium and 2 chloride ions together are found on the __ membrane of the thick ascending limb of the loop of Henle. |
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The cells that make up the walls of the tubule have a membrane that faces the inside or lumen of the tubule and the other, which is in contact with the interstitial fluid. This outer membrane is called the ___ membrane. |
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Water is reabsorbed by following the ___ gradient |
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Hyperglycemia indicates that the amount of glucose in the filtrate exceeds the ___ of the transporters |
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Reclaiming of valued substances from the filtrate, and moving them back into the blood is called: |
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What drives the movement of sodium from the tubule into the PCT cells? |
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This ion leaves the ascending limb of the loop and enters the interstitial fluid by following sodium ions |
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As the filtrate moves from the top to the bottom of the descending limb of the loop of Henle, the osmolarity ___. |
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Co-transport of sodium with glucose and with hydrogen is seen on this membrane of the PCT. |
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As the filtrate moves from the bottom to the top of the ascending limb of the loop of Henle, the osmolarity ___. |
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In the proximal convoluted tubule (PCT), sodium-potassium pumps are found on the ___ membrane. |
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The transport that takes place in the __ limb of the loop of Henle drives the process studied in the countercurrent multiplier system |
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Most substances are moved through the ___ pathway during reabsorption. |
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The movement of __ ions drives the movement of water out of the tubule during reabsorption |
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