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drain urine from bladder during urination (=micturition) m- merges w/reproductive tract, urogenital f- seperate |
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kidney functions maintains- secretes- removes- |
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maintains- water,ion, pH balance secretes hormones removes toxins and metabolic wastes |
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what ions does the kidney maintain in balance? |
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what hormones does the kidney secrete and functions? |
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renin: regulates plasma Na concentration Erythropoietin: stimulate erythrocyte production in bone marrow |
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what toxins and metabolic wastes does the kidney remove? |
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urea, uric acid, creatinine |
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cardiac output to kidneys renal blood flow filtered |
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20-25% 20% 125 mL/min =180L/day |
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What is the filtrate like? |
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same composistion as plasma except is is Mostly protein free |
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When does the filtrate composistion change? |
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as it passes through kidney tubules |
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How does the filtrate composistion change? |
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certain desirable ions/molecules returned to blood (sugars, aa, water) Others are excreted in urine |
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Where is the location and external anatomy of kidneys? |
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retroperitoneally; within paravertebral gutters (curves of ribs) Lateral to T12-L3 vertebrae |
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12cm tall 6cm wide 3 cm thick- bar of soap |
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what is on the concave surface where vessels and nerves enter and exit? |
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what surrounds the kidney? CT |
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renal capsule dense, irregular CT |
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contains uriniferous tubules |
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make up renal medulla collecting ducts (upside down pyramids) |
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just inside the hilus, within the renal sinus |
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2 total, drain into renal pelvis |
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several (7-13) drain into major calyces |
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collecting ducts in the renal pyramids drain into and through? |
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into minor calyces thru openings at papillae of pyramids |
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what is the flow of filtrate from collecting ducts? |
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collecting ducts thru: openings in papillae of pyramids to: minor calyces to major calcyce to renal pelvis to ureters (urine) |
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what are uriniferous tubules, and what are they composed of? |
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=renal tubules, composed of Nephron and collecting duct |
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renal corpuscle plus renal tubules |
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What is the collecting duct in the uriniferous tubules involved in? |
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What types is the renal corpuscle? |
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glomerulus and glomerular capsule |
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twisted ball of blood capillaries which are fenestrated |
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what is the glomerular capsule? |
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Bowman's capsule parietal layer- simple squamous and outer visceral layer- podocytes, covers the glomerular capillaries (foot processes of podocytes) |
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how does the glomerular capsule surround glomeruli? |
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open end where arterioles enter and leave= vascular pole hand in balloon fit |
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what is the glomerular space? |
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surrounds glomeruli within glomerular capsule |
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the route of passage of substances between blood and glomerular space consists of: |
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fenestrae of glomerular capillaries basement membrane/basal laminae filtration slits between podocytes |
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what is the barrier for protein filtration? |
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probably basal lamina of basement membrane maybe protein diaphragm over fenestrae |
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What type of capillary beds are nephrons associated with? |
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each glomerulus peritubular capillaries |
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each glomerulus associated with a nephron is: fed and drained by- afferent- efferent- |
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arterioles afferent arterioles- blood into glomeruli efferent arterioles- blood out of glomeruli |
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peritubular capillaries: arise from- surround: describe: absorb: |
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efferent arterioles surround renal tubules low pressure, porous capillaries absorb solutes, water |
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cortical nephrons- entirely w/in cortex of kidney |
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Juxtamedullary nephrons at junctions of cortex and medulla long loops of henle responsible for kidney's ability to fo |
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Juxtamedullary nephrons responsible for kidney's ability to: |
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form small volumes of concentrate urine |
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vasa recta: part of the kidney's -- system dip down and point: surround: |
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thin-walled looping capillaries urine-concentrating system dip down from base of pyramids toward pointed end into medulla surround juxtaglomerular nephrons |
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