Term
| Physiology of Urinary System Consists of: (2 pts) |
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Definition
-kidneys to form urine
-structures to transport urine |
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Term
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Definition
1. Maintain plasma volume, therefor BP
2. Regulate H20 concentration
3. Acid/base balance (blood pH)
4. Eliminate wastes, drugs & hormones
5. Endocrine organs:
-produce renin
-erythropoetin (RBC formation)
-vitamin D |
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Term
| Functional Unit of Kidney |
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Definition
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Term
| Three Factors Involved in the Formation of Urine |
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Definition
1. Glomerular
2. Tubular Reabsorption
3. Tubular Secretion |
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Term
| Glomerular Filtration (2 pts) |
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Definition
-movement of protein-free plasma from blood into Bowman's apsule by Bulk Flow across filtration membrane
-20% of plasma in glomerulus is filtered |
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Term
| Three Parts of Filtration Membrane |
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Definition
1. Fenestrated Endothelium of Glomerulus
2. Basement Membrane
3. Filtration Slits b/w Podocyte |
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Term
Glomerular Filtration Pressures:
1. Glomerular BP
2. Blood Osmotic Pressure
3. Capsular hydrostatic Pressure
4. Capsular Osmotic Pressure |
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Definition
1. 55mmHg
2. 30mmHg
3. 15mmHg
4. 0mmHg |
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Term
| Glomerular Filtration Rate |
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Definition
-180L/day
-125mL/min
-entire plasma filtred 60 times/day |
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Term
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Definition
-kidney damage
-produces large volume of urine |
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Term
Regulation of Glomerular Filtration Rate:
1. Increased BP
2. Decreased BP |
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Definition
1. Increased GFR
2. Decreased GFR
-direct correlation |
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Term
| Two Types of Regulating GFR |
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Definition
1. Intrinsic Regulation
2. Extrinsic Regulation |
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Term
| Two Kinds of Intrinsic Regulation of GFR |
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Definition
1. Myogenic (MAP)
2. Juxtaglomerular Apparatus |
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Term
| Myogenic Regulation of GFR |
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Definition
| Increased BP --> Stretch --> Smooth Muscle Contraction --> Restricts Blood Flow --> Decreases GBP (glomerular BP) |
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Term
| Juxtaglomerular Apparatus |
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Definition
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Term
| Extrinsic Regulation of GFR (5 pts) |
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Definition
-under extreme low MAP
-SNS -> vasoconstraction
-afferent arteriole = < flow to glomerulus
-efferent arteriole = blood backs up in glomerulus
-extreme stress = |
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