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urinary system
classification
38
Pharmacology
Undergraduate 1
10/02/2009

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Term
aminoglycosides
Definition
binds to ribosome, inhibits bacterial protein synthesis. Gram negative.  neomycin-neofradin, streptomycin-streptomycin, gentamycin-garamycin
Term
carbapenems
Definition
inhibit bacterial cell wall synthesis.  broad spectrum.  resist to beta-lactamase enzymes.  ertapenem/invanz, imipenem/primaxin, meropenem/merrem
Term
Cephalosporins
Definition
inhibits bacterial cell wall synthesis.  related to penicillin.  !st generation effective against gram positive, 2nd & 3rd generation have increased activity against gram-negative oranisms.  4th generation is broad spectrum.  cephalexin/keflex, cefprozil/cefzil, ceftriaxone/rocephin 
Term
glycyclines
Definition
new family of antibiotics. binds to 30S ribosome, preventing protein synthesis.  bacteriostatic.  used to treat broad spectrum gram positive, gram-negative, and anaerobic infections.  tigecycline
Term
ketolides
Definition
bactericidal.  prevents bacterial ribosomes from translating its mrna into new protein.  used to treat acute bacterial sinusitis, bronchitis, and lung infection
Term
macrolides
Definition
inhibit protein synthesis. Bacteriostatic and bactericidal.  used for respiratory, gastrointestinal tract skin and soft tissue infection. Used when penicillin, cephalosporin, and tetracycline are contraindicated.  erthromycin/E-mycin, azithromycin/zithromax, clarithromycin/Biaxin
Term
penicillin
Definition
inhibits cell wall synthesis. significant of penicillinase-resistant penicillins.  used for ear infection, pneumonia, meningitis, urinary infection, syphilis, gonorrhea.   amoxicillin/amoxil, ampicillin/principen, amoxicillin and potassium  clavulanate/ augmentin 
Term
bacteriostatic
Definition
inhibit the growth of bacteria
Term
quinolones
Definition
new subclass is used for broad spectrum coverage.  cipro, levaquin
Term
streptogramins
Definition
inhibits protein synthesis, new class developed from pristamycin. quinupristin/dalfopristin. used to resist vancomycin resistant infection
Term
sulfanamides
Definition
inhibits bacterial biosynthesis of folic acid resulting in cell death.  used to treat urinary tract infections an d otis media.  used prophylactically in pt susceptible to strep infection or reumatic fever. trimethroprim/sulfamethoxazole/ bactrim
Term
tetracyclines
Definition
inhibits protein synthesis. VD, UTI, URTI, pneumonia, and meningitis when penicillin is contraindicated.  tetracycline/sumycin, 
Term
antitubercular agent
Definition
ehambutol/myanbutrol, isoniazid/INH: prevention and treatment, but action unknown.  rifampin/rifadin.  tx fro Tb multifacet & protracted
Term
gram negative aerobic bacilli from gastrointstinal tract.
Definition
e coli, staph, pneumonia  also other oranisms enterbacter, proteus mirabilis, pseudomonas aeruginosa
Term
drug therapy for uti
Definition
fosfomycin/monurol, quinolone, nitofutantoin/macrodantin
Term
urinary anticholinergic agent
Definition
oxybutynin/ditrpan, solifenacin/vesicare, tolterodine/detrol
Term
other urinary agents
Definition
neostigmine/prostigmin,  phenazopyridine hydrochloride/pryidium  reddish/orange urine
Term
opiate agonist, the nursing process includes?
Definition
premedication assessment and planning & knowledge of antidotes.  Do not administer if respirations below 12.
Term
opiate agonist expected side effects
Definition
light-headedness, dizzyness, seation,nausea, sweating, confusion, disorientation, orthostatic hypertension, constipation
Term
opiate agonist, report these side effects
Definition
respiratory depression, urinary retension, overabuse, or abuse.  itching-benadryl.  urinaty retention- 30 ml of urine per hr 
Term
opiate agonist, interactions
Definition
CNS depressants may enhance depressants effect, some enzymes-inducing agents may intereact negatively
Term
ceiling effect
Definition
the optimal potential effect of a med.  once a therapeutic limit is reached, increases in dose may produce side effects but no further beneficial effects.
Term
what pain management drug classification has ceiling effect?
Definition
opiate partial agonist
Term
opiate partial agonist.  pharmacologic action depend on whether.....
Definition
an ipiate has been previously administered.  dependence to the opiate agonist exist
Term
effective analgesic without prior administration of opiate agonists
Definition
opiate partial agonists
Term
used in presents of opiate dependence, opiate partial agonist will induce wiothdrawal symptoms
Definition
opiate partial agonist
Term
opiate partiial agonist , nursing process
Definition
premedication assessment and planning.  check for prior use of opiate agonist.
Term
opiate partial agonist expected side effects
Definition
clamminess, dizziness, sedation, nausea, dry mouth, sweating, constipation
Term
opiate partial agonist, report these side effects
Definition
confusion, disorientation, hallucination, repiratory depression, overuse, or abuse
Term
opiate partial agonist, drug interaction
Definition
CNS depressant, opiate agonists
Term
opiate antagonist
Definition
reverse the respiratory depression, sedation, and hypotension associated opiate agonist and opiate partial agonist
Term
three closely related opiate antagonists are
Definition
nalmefene, naloxone, naltrexone, narcan.  "pure" opiate antagonist. (no effect on its own other than reversing CNS depressant effect of opiods and propoxyphene.)treat resp depression when excessive doses administered
Term
Salicylates
Definition

slight to moderate pain.                      analgesic, antipyretic, and antiiflammatory

prostaglandin inhibitors

conscious level not dulled, memory, sedation

Term
do not exceed _ grams a day of apap
Definition
4
Term
miscellanrous analgesics names
Definition
darvocet, lortab, percocet, tylenol w codeine, vicodin
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