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Urinalysis
Vocab. Tests
135
Health Care
Undergraduate 1
06/12/2010

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Cards

Term
Anuria
Definition
A complete stoppage of urin flow
Term
Appearance
Definition
refers to the clarity of the urine
Term
Bilirubin
Definition
product in the breakdown of hemoglobin; main pigment in bile
Term
Control
Definition
A sample with a known value used to determine the accuracy of a method
Term
Concurrent Mechanism
Definition
Selective reabsorption process that serves to maintain the osmotic gradient
Term
Distal
Definition
Farthest from a point
Term
Diuresis
Definition
passage of abnormally large amounts of urine
Term
Dysuria
Definition
Pain on urination
Term
Edema
Definition
Tissue swelling to excessive fluids
Term
-emia
Definition
relating to blood
Term
Filtration
Definition
Forcing fluids and dissolved substances through a membrane by pressure
Term
Glycolysis
Definition
Splitting of glucose into smaller fragments
Term
Glycosuria
Definition
glucose in urine
Term
Glucose Oxidase
Definition
an enzyme that catalyzes the oxidation of glucose to gluconic acid and H2O2
Term
Homeostasis
Definition
The tendency in biologic systems to maintain relatively constant conditions in the internal enviroment
Term
Hypersthenuria
Definition
A condition where urine has a specific gravity greater than the 1.010 SG of plasma filtrate
Term
Hyposthenuria
Definition
A condition where th urine has a specific gravity less than the 1.010 SG of plasma filtrate
Term
Hydrometer
Definition
A weighted glass rod that measures density of a solution by depth at which the glass rod  floats in the liquid
Term
Hemoglobinuria
Definition
Free hemoglobin in urine
Term
Hematuria
Definition
Intact red blood cells in urine
Term
Isosthenuria
Definition
A condition where urine has a specific gravity equal to the 1.010 SG gravity of the plasma filtrate
Term
Ketone Bodies
Definition
Degradation products of fatty acids
Term
Ketonuria
Definition
Ketone bodies in urine
Term
Leukocyte Esterase
Definition
an enzyme found in leukocytes
Term
Melanogen
Definition
A colorless chromagen that will darken when exposed to light
Term
Multistix
Definition
A plastic strip with varying numbers of test pads which are impregnated with different reagents to assay(test) a specific analyte
Term
Myoglobin
Definition
A heme protien found in striated muscle, which after a crushing injury is released into circulation and can be easily filtered by the glomerulus
Term
Nephritis
Definition

Inflammation of the kidney involving glomerulus, tubules, and/or interstitial tissue.

 

(Neph)-Kidney

 

(itis)-inflammation

Term
Nocturia
Definition
Excessive urination during the night
Term
Oliguria
Definition
A decrease in daily urine output; typically less than 500cc/day
Term
Orthostatic Proteinuria
Definition
A condition where protein will be present in the urine only after patient has been in a vertical position for prolonged periods.
Term
Osmotic Gradient
Definition
A difference in salt concentration
Term
Peristalsis
Definition
A progressive wave of contraction and relaxation of a tubular muscular system in which contents are forced through a system
Term
Peridoxase
Definition
A second enzyme that catalyzes the reaction of hydrogen peroxide with a potassium iodide chromagen to colors ranging from green to brown
Term
pH
Definition
The measurement of the hydrogen ion concentration
Term
Phenylketonuria
Definition
A genetic condition that is characterized by the accumulation of plasma phenylalanine
Term
Polydipsia
Definition
Excessive thirst
Term
Polyuria
Definition
A marked increase in urine flow
Term
Protienuria
Definition
Protien in urine
Term
Proximal
Definition
Meaning nearest to the point
Term
Pyuria
Definition
Pus in the urine
Term
Reabsorption
Definition
The process of bringing fluids and dissolved substances through a membrane back into the body
Term

Refractometer

(Index Refractometer)

Definition
An instrument used for indirectly determining specific gravity by refractive index
Term
Renal
Definition
Pertaining to the kidney
Term
Renal Calculi
Definition
Term for kidney stones
Term
Secretion
Definition
The process of bringing fluids and dissolved substances through a membrane into the filtrate in the kidneys
Term

Specific Gravity

(SG)

Definition
The ratio of weight in a volume of fluid compared to the weight of an equal volume of distilled water at a constant temperature
Term

Tamm-Horsefall

(Uromodulin)

Definition
Mucoprotein Secreted by the renal tubules
Term
Threshold substance
Definition
A substance which is almost completly reabsorbed by the renal tubules when their concentration in plasma is within normal limits
Term
Turbidity
Definition
A cloudiness; a disturbance of solids(sediment) in a solution
Term
Urobilinogen
Definition
One of several reduction products seen during the breakdown of bilirubin
Term
Urea
Definition
A metabolic waste product produced in the liver from the breakdown of protein and amino acids
Term
-urea
Definition
Refers to urine
Term
Urinometer
Definition
An instrument used for directly measuring the SG of urine
Term
Urology
Definition
A branch of medicine concerned with the male and female urinary tract and male genital tract
Term
Volatilization
Definition
A conversion of liquid into a vapor
Term
Urine
Definition

Fluid containing 95% Water and 5% Metabolic products.

Secreted by the kidneys, and stored in the bladder

Discharged by way of the urethra

Term

Main Constituents of Urine

 

 

 

Organic Substances

Definition

Water

 

 

Creatinine

urea

uric acid

 

Term
Inorganic substances of Urine
Definition

Chloride, Sodium, Potassium

Hormones

Vitamins

Medications

 

Term

How many grams of dissolved material is excreted every 24 hours?

 

 

Half of Which is what?

Definition

60 Grams of dissolved material is excreted every 24 hours

 

Half of which is Urea

Term
Average Volume of Urine Output Daily
Definition

Daily output: 1200-1500 mL

 

(may be cnsidered normal range): 600-2000 mL

Term
Urinalysis
Definition
Physical, Chemical, and Microscopic analysis of urine for diagnosiss of disease and to follow the course of treatment
Term
Anatomical Components of urinary system
Definition

Kidneys

Ureters

Bladder

Urethra

Term
Kidney Physical Characteristics
Definition

Bean Shaped

Size of a clenched fist

Concave side facing inwards

Term
Kidney location
Definition

Located at the back of abdominal wall above the waist

Right kidney sits just below the liver

Left kidney is below the diaphragm adjacent to the spleen

Term
Kidney Size and weight
Definition

11 cm long

5 cm thick

Weight: 150 G

Term
Located above each kidney
Definition
Adrenal Glands
Term
Cortex
Definition

Outer Portion of Kidney

Reddish in color

Term
Medulla
Definition

Inner Portion

Containes minor calices, major calices, and the renal pelvis

Term
Minor Calices
Definition
Drains urine from the collecting ducts into the major calices
Term
Major Calices
Definition
Drains Urine from minor calices into the renal pelvis
Term
Renal Pelvis
Definition
Drains urine from the major calices into the ureters
Term
Ureters
Definition

Two tubes that connect kidneys to bladder

Measures 28-34 cm long. RIGHT ureter slightly shorter

Activly transports urine to bladder by peristalsis

Term
Bladder
Definition

Elastic and hollow Muscular Sac

Collects and stores urine

500 mL(16 oz) or more

Term
Urethra
Definition

Tube leading from bladder to outside of the body

Transports urine from bladder to outside of the body

Term

Length of urethra

(Male)

 

 

(Female)

Definition

About 24 cm Long

 

 

About 4 cm Long

Term
Kidneys Maintain homeostasis by...
Definition

Regulating the pH, mineral ion concentration, and water composing of blood

Filtering blood and eliminates toxic wates products

 

Performes Endocrine Functions

(Renin abd Erythropoietin) 

Term
Renin is also known as...
Definition
Angiotensinogenase
Term
Angiotensinogenase(Renin) Is produced by...
Definition
The juxtaglomerular Apparatus
Term
The juxtaglomerular Apparatus activates what?
Definition
The Renin-angiotensin system
Term
Angiotensin 1 is converted into angiotensin 2 (Active)Where?
Definition
In the Lungs
Term
Angiotensin 2 corrects renal blood flow by...
Definition

Vasoconstriction

Stimulating reabsorption of sodium

Releasing aldosterone, a sodium retainiing hormone

Term
Erythropoietin
Definition

Hormone produced by the kidneys

Stimulates the body to produce red blood cells

Term
Nepheron
Definition
Functional unit of the kidney
Term
How many nepherons per kidney?
Definition
1-1.5 million
Term
Compononts of the Nephron
Definition

Renal Corpuscle

Glomerulus Within Bowmans Capsule

Renal Tubules

Collecting ducts

Term
Where is the glomerulus located?
Definition

In Cortex

Capillary tuft

Term
What surrounds the glomerulus?
Definition
Bowmans Capsule
Term
What is the Bowmans Space?
Definition
The space between the capillary network and the bowmans capsule
Term
What is the Function of the Glomerulus?
Definition

Siite of Renal(Glomular) Filtration

Main Filter of the Nephron

Allow only LMW(Low Molecular Weight) Substances (Less than 70,000) To pass through membrane.

Semi-permeable

Term
What are renal tubules?
Definition
Elongated tube that transports glomerular filtrate from glomerulus to collecting duct
Term
3 Sections of the renal Tubules
Definition

Proximal Covoluted Tube

Loop of Henle

Distal Convoluted tube

Term
Functions of the renal tubule
Definition

Reabsorption(80%)

Secretion

Term
Functions of the loop of henle
Definition

Controls Specific Gravity, volume, and pH

Also dilutes and concentrates

Term
Functions of The Distal Convoluted Tubule...
Definition

Adjusts pH, osmolality, and Electrolyte Content of the Urine

Reabsorption and Secretion

90% of Solutes bt the time filtrate reaches distal tubules

Term
Collecting ducts location..
Definition

Located in cortex and Medulla

One collecting tubule attaches to several different nephrons

Term
Function of collecting ducts
Definition
Collect Glomerular filtrate and transport urine from the collecting tubules to the minor calices
Term
Kidneys Receive blood from where?
Definition

Renal Arteries

20% of Cardiac output or 1 liter of blood per minute

Blood enters the nephrons through the afferent arteriole

Blood exit into the efferent arteriole

Term
Urine is formed by what four actions in the kidneys?
Definition

Glomerular Filtration

Tubular Reabsorption

Renal Concentration

Tubular secretion

Term
First step in formation of urine
Definition

Filtration - forcing fluid and dissolved substances through a membrane by pressure

occurs in the glomerulus (120 mL/min)

Term
Active transport
Definition
The movement of molecule across a membrane that is driven by energy
Term
Passive Transport
Definition
The movement of molecules across a membrane as a result of differences in their concentration
Term

Three Rules for urine Specimen handeling

 

Definition

Collect Specimen in proper container

Properly label all specimens 

Promptly transportspecimens to laboratory. Within one hour

Term
Urine Specimen collection containers
Definition

Random or first morning collections

Mid stream, clean catch Collections

24 hour specimen collections (May Require Chemical Preservation

Term
For routine screenings, physical exams, and drug or alchohol screenings
Definition
Random or routine collection
Term
First Morning collection
Definition

Increased concentration in the urine

hormone or chemical tests, pregnancy sccreening, helps evaluate for orthostatic protienuria

Term
Steril or midstream catch
Definition

Increased sample stelility

Bacteriologial studies

Increases accuracy of microscopic exam

Term
fasting specimen
Definition

8-12 hours fasting

Collect second specimen

Recommended for glucose monitoring

Term
Two Hour Post Prandial Method
Definition

Monitor insulin therapy

Glucse level

Term
Glucose tolerance test (GTT)
Definition

Measures patients ability to metabolize glucose

Concerned with glucose and ketone level

8-12 hours fasting

Void after fasting

Ameasured amount of glucose is given to patient. (Glucola, or 10g of glucose per minute.)

Amount given to pt is determined by the physician

Consume within 5-10 minutes

Specimens at one hour intervals are collected after drinking the solution

Term
Purpoce of Urine Preservatives
Definition
Prevents changes in bacterial growth, Turbidity, Nitrite, pH, Glucose, ketones, bilirubin, urobilinogen, And cellular decompostition(RBC, WBC, Epi cells, Casts and crystals, and parasites)
Term
Refrigeration
Definition

(2-8 degrees C)

Most Common

Advantages are no chemical interference, Drecreased bacterial growth and metabolism

Disadvantages are Precipitates some crystals( amourphous phosphates, amorphous urates), and raises specific gravity

Term
Toulene
Definition

Advantage - Does not interfere with routine chemical tests

Disadvantage - Floats on surface, Ineffective against bacteria

Term
Formaline
Definition

Advantage - Excellent for sediment preservative

Disadvantage - Precipitate protein, interferes with copper reduction, glucose, blood, leukocyte esterase

Term
Thymol
Definition

Advantage - Preserves Glucose and sediment

Disadvantage - Interferes with urine sediment, and may cause cellular damage

Term
Chloroform
Definition

Advantage - Inhibits bacterial growth

Disadvantage - Interferes with urine sediment, and may cause cellular changes

Term
Boric Acid
Definition

Advantages - Preserves Protien, Preserves Formed elements, and Does not interfere with routine tests except pH

Disadvantages - May precipitate crystals

Term
Sodium Fluoride
Definition

Advantages - Prevents Glycolosis, good preservative for drug analysis

Disadvantage - Inhibits dipstick test for glucose, blood and leukocyte

Term
Hydrochloric acid
Definition

Advantages - Bacteriacidal

Disadvantages - Harmfl to patients, destroyes formed elements, precipitates solutes, interferes with routine analysis

Term
Freezing
Definition

Advantages - Preserves bilirubin and urobilinogen, and useful for some chemical analysis

Disadvantages - Destroys formed elements, and turbidity occurs

Term
Purpose of visual examination of urine
Definition

Screening test  to aid in the detection and diagnosis of renal, urinary tract and systemic diseases.

used to detect abnormal color, volume, odor, and appearance

Method - Macroscopic Examination

Term
Normal values for visual exam
Definition

Color - Pale yellow to amber

Appearance - Clear or transparant

Odor - Faint aromatic color

Term
no color in urine
Definition

large fluid intake

 

Term
Pale yellow
Definition

Normal color (unchrome)

Common in random collection

Increased fluid intake

Diuertics Patients with polyuria

Term
Dark Yellow
Definition

Concentrated urine

Common in first morning void

Term
Dark Amber
Definition

Dehydrated pt

Sever Burns

Fever

Term
Presence of yellow foam
Definition
Bilirubin
Term
Medications(Pyridium)
Definition
Pyridium, yellow orange color
Term
Pink to red
Definition

Intact RBC's

Hemoglobin(Intravascular hemolysis)

Myoglobin( Muscle damage)

Pigments in blood(Beets)

Menstrual contaminatiion

Medications

Porphyrins - port wine colored urine

Term
Brown to black
Definition

Old or lysed RBC's

Melanin or melanogen

Homogentisic Acid (Alkaptonuria)

(Metabolite of phenylelanin )   

Term
Blue/green
Definition

Large amounts of bacteria

(Pseudomonas ssp)

Breath deoderizers(Clorets)

Phenol derivatives

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