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Details

Upper GI pharmnacology
drugs of upper GI
19
Dentistry
Professional
09/19/2012

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Cards

Term
Metocloprimide
Definition
Binds 5-HT receptor.  Antiemetic.  Gastric mobility in ind. w/ gastroparesis
Term
Loperamide
Definition

Slow colon emptying.  Anti-diarrheal

 

Term
Diethylproprion HCl
Definition
suppress appetite by increasing catecholamines, habit forming
Term
Ephrine drugs
Definition
Appetite suprressants.  Includes ephedra
Term
Cotazyme
Definition
treat pancreatic insuficiency
Term
Decholin
Definition

A tri-keto bile salt that increases bile flow - forms small micelles and increases osmotic pressure of bile. 

Term
Medium chain fatty acids
Definition
useful for lipid nutrition in ind. w/ insufficiant bile acids...do not require bile acids to be absorbed
Term
Chendiol
Definition
Gallstones - suppresses hepatic cholesterol synthesis
Term
Actigall
Definition

Bear bile

Gallstone tx - shift cholesterol/bile acid/phospholipid to liquid crystal phase for easier excretion

Term
Aspirin, Ibuprofin
Definition
Cox-1 inhibitors - lower prostaglandins - decrease cytoprotective mech in stomach - propensity for ulcers
Term
Acetominaphen / Celebrex
Definition
Alternative to Cox-1 - less gastric side-effect
Term
Cimetidine and other "idines"
Definition
H2 blocker - decrease stomach acid
Term
Pirenzepine
Definition
Muscarinic agonist - prevent Ca++ entry into cells - decrease stomach acid
Term
Sucralfate
Definition
Ulcer tx - mucosal protective agent
Term
Omeprazole
Definition
Acid reducer - H/K ATPase blocker
Term
Carbenoxlone
Definition
mucosal protection agent for stomach
Term
Misoprostol
Definition

PGE-1 analogenhance mucosal barrier; lower c-AMP in

parietal cells; many side effects at

therapeutic doses; induce labor

Term
Ranitidine
Definition
H2 antagonist - more potent than cimetidine
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