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Unit 6
endocrine/psych
10
Other
Graduate
07/07/2014

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Term
Thyrotoxicosis syndrome
Definition
hyperthyroidism
graves
Nervousness
Weight loss
Symptoms of heart failure or fatigue
Muscle weakness, mostly in proximal muscles, in absence of local muscle disease (other than some atrophy)
Trophic skin changes
Heat intolerance
Shortened contraction and relaxation phases of deep tendon reflexes
Hypokalemic periodic paralysis (minutes to days, may be brought on by exercise)
Demineralization and fractures
Thyroid dermopathy - thickening of skin
Onycholysis (loosening of nails)
Term
Hypothyroidism
Definition
Kidney stones
Peptic ulcers
Mental changes
Proximal muscle weakness and fatigability
There may be glove and stocking sensory loss and loss of vibratory sense
Reflex changes
Term
hyperparathyroidism
Definition
Chondrocalcinosis
Gout
Subchondral fractures
Peri-articular calcific deposits
Term
Hypoparathyroidism
Definition
Depression
Paresthesia
Muscle cramp
Psychosis
Seizures (possibly life threatening)
Tetany or latent tetany: Note positive Chovstek’s sign: tapping of facial nerve causing contraction around the mouth, and Trousseau’s sign: rapid development of spasm in hand when a blood pressure cuff is applied to the upper arm.

Calcification of basal ganglia, may be asymptomatic or present as chorea, tremors, and Parkinsonism
Term
Acromegaly
Definition
1) Skeletal changes

Tallness
Hypertrophy of mandible, leading to prognathism
Hypertrophy of most facial bones, phalanges, metacarpals, and metatarsals
Barrel-shaped chest
Kyphosis
Prominent joints


2) Failure of multiple body systems

Hypertension
Congestive heart failure
Hypertrophy of viscera
Diabetes
Kidney stones
Term
Conversion disorder
Definition
According to the Diagnostic and Statistical manual of Mental disorders 4th ed. this denotes pain-free loss of physical function, suggesting a physical disorder. These symptoms, which the patient does not consciously produce, do not have an identified physical explanation. The demonstration of psychological stress or conflict is a prerequisite for the diagnosis. Symptoms mediated by the autonomic nervous system are excluded.
Term
Somatoform pain disorder
Definition
This disorder is characterized by:

Presence of pain >6 months, in absence of pathophysiology that can account for changes in pain or for the severity of pain. This includes most cases of chronic pain and frequently depression is involved
Explanations include self-punishment, loss of effective modulation of afferent signals, and psychological distress
Note that somatic expression (pain) of these disorders is socially acceptable and gets social and professional attention and postpones tackling the underlying psychological problem
Term
Somatization disorder
Definition
This is another disorder without organic findings, characterized by a history of multiple somatic complaints, beginning before the age of 30.

Complaints typically involve most organs
The clinical presentation tends to be dramatic
There is a detailed history of hospitalizations and over-treatment
A high incidence of concurrent psychiatric disorders.
Term
Hypochondriasis
Definition
Unrealistic, chronic fear of serious disease
o based on physical sensations

Frequently associated with depression
Term
alcohol CAGE
Definition
Have you ever felt you should Cut down on your drinking?
Have people Annoyed you by criticizing your drinking?
Have you ever felt bad or Guilty about your drinking?
Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hangover ( Eye-opener)?
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