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hyperthyroidism graves Nervousness Weight loss Symptoms of heart failure or fatigue Muscle weakness, mostly in proximal muscles, in absence of local muscle disease (other than some atrophy) Trophic skin changes Heat intolerance Shortened contraction and relaxation phases of deep tendon reflexes Hypokalemic periodic paralysis (minutes to days, may be brought on by exercise) Demineralization and fractures Thyroid dermopathy - thickening of skin Onycholysis (loosening of nails) |
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Kidney stones Peptic ulcers Mental changes Proximal muscle weakness and fatigability There may be glove and stocking sensory loss and loss of vibratory sense Reflex changes |
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Chondrocalcinosis Gout Subchondral fractures Peri-articular calcific deposits |
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Depression Paresthesia Muscle cramp Psychosis Seizures (possibly life threatening) Tetany or latent tetany: Note positive Chovstek’s sign: tapping of facial nerve causing contraction around the mouth, and Trousseau’s sign: rapid development of spasm in hand when a blood pressure cuff is applied to the upper arm.
Calcification of basal ganglia, may be asymptomatic or present as chorea, tremors, and Parkinsonism |
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1) Skeletal changes
Tallness Hypertrophy of mandible, leading to prognathism Hypertrophy of most facial bones, phalanges, metacarpals, and metatarsals Barrel-shaped chest Kyphosis Prominent joints
2) Failure of multiple body systems
Hypertension Congestive heart failure Hypertrophy of viscera Diabetes Kidney stones |
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According to the Diagnostic and Statistical manual of Mental disorders 4th ed. this denotes pain-free loss of physical function, suggesting a physical disorder. These symptoms, which the patient does not consciously produce, do not have an identified physical explanation. The demonstration of psychological stress or conflict is a prerequisite for the diagnosis. Symptoms mediated by the autonomic nervous system are excluded. |
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This disorder is characterized by:
Presence of pain >6 months, in absence of pathophysiology that can account for changes in pain or for the severity of pain. This includes most cases of chronic pain and frequently depression is involved Explanations include self-punishment, loss of effective modulation of afferent signals, and psychological distress Note that somatic expression (pain) of these disorders is socially acceptable and gets social and professional attention and postpones tackling the underlying psychological problem |
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This is another disorder without organic findings, characterized by a history of multiple somatic complaints, beginning before the age of 30.
Complaints typically involve most organs The clinical presentation tends to be dramatic There is a detailed history of hospitalizations and over-treatment A high incidence of concurrent psychiatric disorders. |
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Unrealistic, chronic fear of serious disease o based on physical sensations
Frequently associated with depression |
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Have you ever felt you should Cut down on your drinking? Have people Annoyed you by criticizing your drinking? Have you ever felt bad or Guilty about your drinking? Have you ever had a drink first thing in the morning to steady your nerves or get rid of a hangover ( Eye-opener)? |
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