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UNit 5
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46
Biology
9th Grade
11/18/2009

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Term
transcription
Definition
uses RNA polymerase and creates mRNA from DNA template-1.) helicase breaks hydrogen bonds between the nitrogen bases 2.) DNA strand breaks apart 3.)RNA Polymerase brings in mRNA nucleotides and matches them with their DNA complement.
Term
where does transcription happen
Definition
nucleus
Term
translation
Definition
1.)mRNA leaves nucleus and gets to ribosome 2.)tRNA uses anticodon to bring amino acid to the ribosome 3.) tRNA temporarily bonds to mRNA and puts amino acid in place on the new protein
Term
where does translation occur
Definition
in ribosome which is in cytoplasm
Term
gene expression
Definition
process by which the info in a gene is used to create a protein
Term
gene
Definition
segment of a DNA molecule that codes for a specific protein
Term
codon
Definition
group of 3 nucleotides on mRNA that specify a particular amino acid
Term
amino acid
Definition
building block (monomer) of a protein
Term
How do enzymes help in the protein synthesis process
Definition
2 enzymes r needed to make proteins-Helicase and Polymerase
Term
Helicase
Definition
breaks the hydrogen bonds between nitrogen bases(transcription)
Term
Polymerase
Definition
brings new nucleotides and bonds them to existing strands
Term
3 over all things that occur during protein synthesis.....
Definition
1.) DNA unzips and exposes the sequence of nitrogenous bases to mRNA 2.) transcription 3.) translation
Term
protein synthesis
Definition
process in which the genetic code in DNA is carried by messenger RNA (mRNA) to ribosomes to produce specific proteins from amino acids
Term
wat has to happen to the mRNA before it leaves the nucleus
Definition
it needs to be sliced, DNA is spilt into introns and exons and enzymes cut the introns out and leave exons
Term
anticodon
Definition
goes with tRNA, corresponds to codon of mRNA
Term
bonds between amino acids
Definition
peptide bonds
Term
polypeptide chain
Definition
protein
Term
Gregor Mendel
Definition
determined that traits were passed from generation to generation.
Term
Frederick Griffith - 1928
Definition
That somehow the dead bacteria have passed their disease-causing substance to the harmless, living bacteria
Term
Oswald Avery - 1944
Definition
Avery’s team determined that genes are composed of DNA, not protein
Term
Erwin Chargaff
Definition
Chargaff discovered that DNA has the same amount of adenosine as thymine and the same amount of cytosine as guanine. A = T and G = C
Term
Rosalind Franklin & Maurice Wilkins
Definition
used x-ray diffraction to discover that DNA was a double helix
Term
Watson and Crick - 1953
Definition
won a Nobel Prize for discovering the structural model of DNA.
Term
A NUCLEOTIDE
Definition
phosphate group, 5 carbon sygar, nitrogen base
Term
purine
Definition
adenine and guanine- double ring
Term
pyrmindine
Definition
thymine and cytosine-single ring
Term
types of RNA
Definition
transfer, messenger, ribosmal
Term
Located in nucleus
Definition
DNA and RNA
Term
located in cytoplasm
Definition
RNA, DNA-only in prokaryote cells
Term
stores genetic info
Definition
DNA
Term
functions in protein synthesis
Definition
DNA and RNA
Term
gene mutation
Definition
changes in genetic material,parts of the DNA will have a nitrogenous base (or more) missing, added, or exchanged
Term
sickle cell anemia
Definition
genetic disorder caused by fefect in genes
Term
how common r mutations
Definition
very common, approximately 6 mutations in every cell
Term
are all mutations seen
Definition
No b/c not all DNA makes proteins-junk DNA
Term
junk DNA
Definition
DNA sequences between genes tht dont code 4 any proteins
Term
2 big branches of gene mutation
Definition
point mutation and frameshift
Term
pt mutations
Definition
change in DNA at one pt
Term
WAts one type of pt mutation
Definition
substitution mutation- one nitrogen base is dropped and another one pops in
Term
frameshift
Definition
when a nucleotide is added or deleted, and the groupings are shifted
Term
what are the two types of framshift
Definition
insertion- an extra nitrogen base is added deletion- one nitrogen base is removed
Term
wat causes mutations
Definition
mutagens, natural errors durin DNA replication
Term
mutagens
Definition
something tht causes DNA code to change EXamples- xrays, harmful chemicals
Term
wat mutation has least affect
Definition
substiitution
Term
wat/wen mutation has most affect
Definition
frameshift, wen it occurs in sex cells, or early embroyonic cells
Term
wat mutations r passed on
Definition
ones tht occur in sex cells
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