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Unit 5
Infectous Diseases
68
Health Care
Undergraduate 1
10/23/2008

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Term
Nosocomial
Definition
Infectous diseases acquired as a result of medical procedures or in a medical facility, may be more virulent than typical infections
Term
Endemic
Definition
Given to occur in a particular geographic region
Term
Epidemic
Definition
Rapid increase and spread of incidence of a disease
Term
Fomite
Definition
An inanimate object that is contaminated with pathogenic microbes
Term
Parenteral Route
Definition
Portal of entry is through the skin via wounds, incisions, injections or bites
Term
Viremia
Definition
the presence of viral particles in the blood stream
Term
Bacteremia
Definition
The presence of bacteria in the blood stream
Term
Innoculum
Definition
The total number or amounts of microbes introduced into the body
Term
Anitbody-mediated immunity
Definition
The body produces antigen specific immunoglobulin antibodies against ivading microbes
Term
Cell-mediated immunity
Definition
the body produces antigen specific cells which destroy invading microbes or infected cells
Term
Amnestic Response
Definition
"Immunological memory", the body reacts more rapidly and effectively against previously enoucntered antigens
Term
Active immunity
Definition
Long lasting immunity due to the body's own reponse to an anitgen
Term
Passive Immunity
Definition
Short term immunity as a result of injecting antibodies into the body from an outside source
Term
Aseptic Technique
Definition
Procedures followed and practiced by health and care givers intended to prevent or limit the spread of infectous diseases
Term
Disinfect
Definition
To greatly reduce the number of microbes through cleansing and antiseptics
Term
Immunological Test
Definition
Clinical procedures done to detect the presence of antigen-specific antibodies in teh blood or virus specific nucleic acids in cells and tissues
Term
Antimicrobial Drugs
Definition
Chemotherapeutic agents(drugs) which are intended to kill or impair the microbes that cause disease when given to the patient
Term
Anti-infectives
Definition
Antimicrobial drugs that are "man Made", sythesized in the laboratory
Term
Bacteriostatic
Definition
Limits the growth and reproduction of bacteria, allowing the body's defenses to resolve the infection
Term
Prions
Definition
Proteinaceous infectious particles
Term
Bacteriocidal
Definition
Kills the pathogenic bacteria in the body
Term
Dinoflagellates
Definition
unicellular aquatic and marine algea
Term
Pathogenic
Definition
The ability of a microorganism to inflict harm and cause disease
Term
Helminth Parasites
Definition
Parasitic worms
Term
Chlamydia
Definition
Intracellular parasitic bacteria similar to Rickettsia, use humans as nautral reservoir and do not require arthropod vectors
Term
Inflammatory Response
Definition
The body's reaction to microbial harm or damage; vasodialtion (redness), swelling (edema), pain, heat and impaired functioning
Term
Mold
Definition
multicelluclar fungi
Term
Hyphae
Definition
Microscopic filaments of mold which grow throughout whatever substance the mold is living on; they secrete digestive enzymes and absorb nutrients
Term
Intoxication
Definition
damage inflicted as a result of exposure to a m icrobial toxin
Term
Endotoxins
Definition
Poisonous substances released when microbes die and disintegrate
Term
Mycelium
Definition
A large aggregation of fungal hyphae, often visible to the naked eye
Term
Extotoxins
Definition
Poisonous substances released by living, metabolizing microorganisms
Term
Allergic Reaction
Definition
Hypersensitivity immune reaction to microbial antigens
Term
Yeasts
Definition
unicellular fungi
Term
opportunistic invader
Definition
microbial forms, especially fungi, which cause harm by taking advanteage of weakened host defenses or conditions conductive to their growth
Term
ciliates
Definition
protozoa which swim about by means of cilia
Term
Amoebae
Definition
protozoa which creep about via pseudopodia
Term
Eukaryotic
Definition
A cellular form that is characterized by a membranous nucleus and other intracellular membranous organelles. characteristic of protozoa, fungi, plants and animals
Term
Immunosuppression
Definition
A weakening of the body's immunity and resistence to other infections
Term
colonization
Definition
Refers to when pathogenic microbes can grow on or in a host without inflicting any noticeable harm
Term
virulence
Definition
the extent of harm caused
Term
Obligatory
Definition
Requires a specific environmnet and cannot survive in any other condition
Term
Faculative
Definition
Can survive in either aerobic or anaerobic environments
Term
Anaerobles
Definition
microbial forms that do not require oxygen
Term
Aerobes
Definition
microbial forms that use oxygen
Term
Spirilli
Definition
Spiral or cury-shaped bacteria
Term
Bacilli
Definition
Rod-shaped bacteria cells
Term
Cocci
Definition
round-shaped bacteria cells
Term
Morbidity
Definition
The infliction of harm on vital or essential body organs or functions
Term
Mortality
Definition
Death rate
Term
Direct Spread
Definition
Pathogenic microbes are passed directly from one person to another through close personal contact
Term
Sterilization
Definition
A procedure that uses intense heat, pressure, radiation or chemicals that completely destroy all microbial forms and resistant spores
Term
colony
Definition
Bacterial growths that appear as small dots on agar plates, each colony is typically composed of descendants from one bacterial cell
Term
Agar
Definition
A gelatinous substance that serves as the base for nutrient media for culturing microbial forms, especially bacteria, in the laboratory
Term
Arthropod
Definition
insect or insect-related; any member of phylum arthropoda
Term
Prokaryotic
Definition
A characteristic cellular form that does not have a membranous nucleus and other intracellular membranous organelles. Characteristic of Rickettsia and bacteria and related forms
Term
Natural Reservoir
Definition
Those organisms that normally serve as host and source for a particular pathogenic microbe
Term
Retrovirus
Definition
A class of viruses that uses RNA as their genetic material rather than DNA. The host cellsmust convert viral RNA into host DNA via process called "reverse transcription" The normal process of transcription converts DNA into complemenntary RNA. The HIV virus is an example.
Term
Host Immunity
Definition
The defenses against infection possessed by most organisms. It is usulaly th host's immunity that resolves most viral infections.
Term
Provirus
Definition
Dormant viral genes within the host cell. The host cell may continue to normally function until the viral genes become active (if ever)
Term
Tissue Culture
Definition
The procedure of growing living tissues in labortory conditions. The only way in which viruses can be "grown" in the lab is by the culturing the apporopriate host cells
Term
Intracellular Parasite
Definition
A parasite that operates inside a living host cell at the expense of the host cell's normal funcitoning
Term
Virion
Definition
An individual virus outside of its host cell. A "package of genes" incapable of any independent metabolism and reproduction. An inner core of DNA or RNA and an outer capsule of protein
Term
Etiologic Agent
Definition
that which causes a disease. For any given infectous disease, the specific microorganism that causes it.
Term
Infectous Disease
Definition
Any manifestation of harm to the body asa result of the actions of microorganisms. Any disease caused by microorganisms
Term
Indirect spread
Definition
Pathogenic microbes are passed though contract with infected water, food, objects or vectors
Term
Communicable
Definition
Infectous diseases which can be spread or acquired primarily gby indiredct spread
Term
Contagious
Definition
communicable infectous diseases which are relatively easily spread by direct contact.
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