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group of 3 fungus that cause skin disease in animals and humans Ex. ringworm |
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used to test superficial mycoses -test medium changes color when positive (red or blue) |
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identify systemic mycoses |
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-can be toxic to host -check liver and kidney function -fungicidal or fungistatic -affect cell membrane by interfering with RNA and protein synthesis and disrupting fungal cell division |
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-Polyene Antifungals -Imidazole Antifungals -Antimetabolic Antifungals -Superficial Antifungals |
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-Bind to fungal cell membrance -Not well absorbed: Fairly toxic >amphotericin b (Fungione) >Nystatin (Panalog) |
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-One of most well known/popular groups -azole -Cause leakage of fungal cell membrane -systemic mycotic infections and some dermatophyte infections >ketoconazole (Nizoral) >miconazole (Monistat, Conofite) >itraconazole (Sporanox) >fluconazole (Diflucan) >voriconazole (Vfend) |
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-interfere with RNA and protein synthesis -used mainly in combo with other antfungals to treat Cryptococcus infections >fluctosine (Ancobon) |
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-Disrupt fungal cell division -dermatophyte infections >griseofulvin (Fulvicin-U/F, Grifulvin V) >lufenuron (Program) |
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Antimicrobials for Viruses |
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-Limited use -toxic to animal cells -develop resistance to antiviral drugs >acyclovir(Zovirax tablets) ---specific for herpes virus, treats ocular feline herpes virus, side effects-blood disorders such as anemia and leukopenia >interferon(Roferon-A) ---protein substance-stimulates noninfected cells to produce antviral proteins--Roferon-A--orally for treatment of feline leukemia virus and ocular herpes infectionsin cats--side effects rarely seen in cats |
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-live within body of the host and cause internal parasite INFECTIONS |
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-live on body surface of host - cause external paraasite INFESTATIONS |
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-treat arthropod infestations (insects and arachnids) |
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Endoparasites A)Helminths-worms foud in GI tract, liver, lungs and circulatory system> 1)Nematodes (roundworms)-stomach and small intestines, fecal-oral route 2)Platyhelminths (flatworms)--cestodes((tapes)) -trematodes ((flukes)) B)Protozoa |
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treat internal parasitic infections |
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