Shared Flashcard Set

Details

Unit 3
Ch.14 Antifungals and Ch. 15 Antiparasitics
18
Pharmacology
Not Applicable
03/05/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
Dermatophyte
Definition
group of 3 fungus that cause skin disease in animals and humans
Ex. ringworm
Term
Mycosis
Definition
fungal infection
Term
Dermatophyte test media
Definition
used to test superficial mycoses
-test medium changes color when positive (red or blue)
Term
Serologic tests
Definition
identify systemic mycoses
Term
Systemic
Definition
internal infections
Term
Superficial
Definition
skin infections
-Ringworm
Term
Antifungals
Definition
-can be toxic to host
-check liver and kidney function
-fungicidal or fungistatic
-affect cell membrane by interfering with RNA and protein synthesis and disrupting fungal cell division
Term
Antifungal Agents
Definition
-Polyene Antifungals
-Imidazole Antifungals
-Antimetabolic Antifungals
-Superficial Antifungals
Term
Polyenes
Definition
-Bind to fungal cell membrance
-Not well absorbed: Fairly toxic
>amphotericin b (Fungione)
>Nystatin (Panalog)
Term
Imidazoles
Definition
-One of most well known/popular groups
-azole
-Cause leakage of fungal cell membrane
-systemic mycotic infections and some dermatophyte infections
>ketoconazole (Nizoral)
>miconazole (Monistat, Conofite)
>itraconazole (Sporanox)
>fluconazole (Diflucan)
>voriconazole (Vfend)
Term
Antimetabolics
Definition
-interfere with RNA and protein synthesis
-used mainly in combo with other antfungals to treat Cryptococcus infections
>fluctosine (Ancobon)
Term
Superficial
Definition
-Disrupt fungal cell division
-dermatophyte infections
>griseofulvin (Fulvicin-U/F, Grifulvin V)
>lufenuron (Program)
Term
Antimicrobials for Viruses
Definition
-Limited use
-toxic to animal cells
-develop resistance to antiviral drugs
>acyclovir(Zovirax tablets)
---specific for herpes virus, treats ocular feline herpes virus, side effects-blood disorders such as anemia and leukopenia
>interferon(Roferon-A)
---protein substance-stimulates noninfected cells to produce antviral proteins--Roferon-A--orally for treatment of feline leukemia virus and ocular herpes infectionsin cats--side effects rarely seen in cats
Term
Endoparasites
Definition
-live within body of the host and cause internal parasite INFECTIONS
Term
Ectoparasites
Definition
-live on body surface of host
- cause external paraasite INFESTATIONS
Term
ectoparasiticides
Definition
-treat arthropod infestations (insects and arachnids)
Term
anthelmintics
Definition
Endoparasites
A)Helminths-worms foud in GI tract, liver, lungs and circulatory system>
1)Nematodes (roundworms)-stomach and small intestines, fecal-oral route
2)Platyhelminths (flatworms)--cestodes((tapes))
-trematodes ((flukes))
B)Protozoa
Term
Endectocides
Definition
treat internal parasitic infections
Supporting users have an ad free experience!