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Unit 2 Bacteria
Lots of bacteria
36
Medical
Graduate
10/18/2011

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Cards

Term
Shigella
Definition

d:Gram- rod, lactose-, h2s-, non motile, fac-ana, intra

r:only humans, invasive

c:Reiters Syndrome, HUS, bloody diarr

v:plasmid, Shiga toxin, Siderophores, TTSS

t:ceftri, fluroqu, azith, - decreases HUS risk

p: hygiene

Term
E. Coli
Definition

d:gram- rod, lac+, indole+, h2s-, urease-

v:pili, enterotoxins (heat+/-), toxin LT- like cholera, ttss, tfss, icsa: actin motility,

c:gastroenteritis, bloody gastroenteritis, risk of HUS O157:H7, UTIs, Meningtitis, Pneumonia

t:trimethoprim-sulfamethoxazole, amp, cefotaxime,

p:hygiene, cranberry, catheter repl

Term
Salmonella
Definition

d:Gram - rod, motile, some lac, ox-, urease-, h2s+

r:cont food

v:ttss, ipf operon

c:Enterocolitis, enteric fevers(typhoid), sepsis, reiter's, osteomyelitis, pneumonia, meningitis, uptake by m-cells (peyers) and macroph, cf allele resistance, nonbloody diarrh

t: enteric fever-cipro or ceftr

p:vacc, hygiene

Term
Yersinia
Definition

enterocolitica and psedotuburculolis

d:Gram- oval rod, lac-, ur+, motile at 25C, cin agar, sorbitol/orn decarb

v:invades, paralyze macrophage, pili, adhesin, ttss, cnf toxin

c:Reiters, ent:Enterocolitis, high infectious dose, false appendicitis, predisposition, pseu: lzumi fever - vascul, cerv lymph, conj, oral, hand feet

t: supportive, trim-sulf or cipro

p:hygiene

 

Term
Klebsiella
Definition

d:Gram - rod, mot-, encapsulated, h2s -, lac+, indole-, mucoid appearance

v:capsule, ab resist, adheisns

c:currant jelly sputum in pneumonia, bronchitis, UTI, wound infection, catheter infection, iv druggies

Term
Enterobacter
Definition

d:Gram- rod, lac+, indole-

v: endotoxin: cytolsin

c:opportunistic, uti, lower resp, sepsis,

Term
Serratia marcenscens
Definition

d: Gram- rod, indole-, red colonies

c:opportunistic, endocarditis and osteomyelitis in heroin addicts, meningtitis, wound infection, arthritis in peds

t:(all) genta+cefo

p:(all) cath removal, hosp hyg

Term
Proteus/Providencia/Morganella
Definition

d:Gram - rod, lac-, phenyalanine deaminase, urease+ (proteus swarm h2s+), h.o. recent b-lactam

v:antibiotic resistance, pili,

c:UTI, urease->struvite stones

proteus:pneumonia, wound infection,

prov: enteritis, ocular, endocard

morgan:wound, pneum, ophth, cns, pericard, chorioamn, periton,

t:ags, trim-sufa, indole+:ceph

Term
Staphylococcus Aureus
Definition

d:Cata+/Coag+, b-hemo

v:Protein A, Capsule, enterotoxin, exfoliatin, leukocidin, TSStoxin

c:Skin infections, food poisoning, endocarditis, osteomyelitis, pneumonia, TSS, scalded skin syndrome

t:vanco, linezolid

p:hygiene, exp vaccine

Term
Staphylococcus epidermidis
Definition

d:cata+/coag-, g-hemo

v:attach to nylon and plastics, catheters

r:normal flora

p:change catheters, no plastic earrings

Term
Staphylococcus Saprophyticus
Definition

d:Cata+/coag- g-hemo

c:Urinary tract infections honeymoon cystitis

Term
Group A Streptococcus
Definition

S. pyogenes

d:Gram+ b-hemo, cata-, baci-s

v:Pili, streptokinase, streptodornase, hyaluronidase, pyrogenic toxin, erythrogenic toxin, hemolysins, streptolysin O

c:Sore throat..., skin infections, cellulitis, puerperal fever, necrotizing fasciitis, acute glomerulonephritis, rheumatic fever->dental prophylaxis if heart damage

t:bacitracin, penicillin

p:carriers, NO vaccine

Term
Group B Streptococci
Definition

S. agalactiae

d:b-hemo, baci-res

c:baby sepsis and meningitis

p:mother culture/prophy

Term
Streptococcus pneumoniae
Definition

d:A-hemolytic, No lancefield group capsule, bile-s

r:50% of throats

v:capsule

t:lots of resistance

Term
Group D streptococci
Definition

Enterococcus fecalis

d:g-hemo, Bile-r

c:abdominal abscesses, UTI, endocarditis

t:resistance, combos of penicillin and ag's, linezolid

Term
Viridans Streptococci
Definition

d:No lancefield group, A-hemo, bile-r

v:extracellular polysacch, acids

c:Dental caries, Endocarditis, Infected prosthetic joints

t:prophyl

Term
Peptostreptococcus
Definition

d:g-hemo, No lancefield group, Obligate anaerobes, bile-s

c:abscesses

Term
Rickettsia
Definition

d:Gram - short rods, intracellular, would be gram-, immunofl, PCR

r:arthropod vector, murine normal hosts, epidemic-humans host/body lice,

v:invade endoth, ompA/B, tfss, plA2, actA

c:rocky mountain spotted fever, mediterranean spotted fever,epidemic typhus-headache, scrub typhus, murine typhus, brill-zinsser:delayed relapse of epid

t:doxycycline, chloramph- pregn/allerg

Term
Coxiella Burnetti
Definition

Proteobacteria, zoonosis, low inn, 

v:acid phosph-inh resp burst,

c:Q fever, inhalation- no vector, multiplies in alveolar monocytes/macrophages, pneumonia, hepatitis

t:doxy, fluoroq

Term
Ehrlichia and Anaplasma
Definition

d:Gram - tiny rod, WBC intracell->morulae

r:lower mamm, arthopod vec

c:thrombocytopenia, DIC

t:doxy, pregn-fluoroq

peds: exception to get doxy in these/ricketts/qfever

Term
HACEK: haemophilus, actinobacillus, cardiobacterium, eikenella, kingella
Definition

d:fac an, gram- rod, growth reqs, choc not blood, sattelite s.aureus-NAD,

r:flora of upper resp

 

Term
H. influenzae
Definition

v:capsule-multiple, IgA pro,

c:mening-passive from mother, sepsis, epiglot, cellul, arth, brocnh/pneumo, otit, sinus, conjunct,

t:ceftr

p:vaccine

 

h. ducreyi: soft chancre STD, ampicillin

Term
Bordatella
Definition

d:gram- coccobacilli,

v:pili, hemagglutinn, peractin, toxin, adenyl cycl, dermonecrotic, tracheal, LPS

c:convalescent: regen of trachea epi

t:macrolides

p:acell vaccine

 

b. bronchiseptica- zoonosis resp., some bronchopneumo

Term
Neisseria
Definition

d:aer/fac-an, gram- cocci, thayer martin

r:most are normal flora

lack virulence, can cause soft tissue infection

Term
n. meningitidis
Definition

d:g-diplococci, LPS, ox+, cat+, lac/suc-, mal+, choc not blood

r:human nasophary

v:encapsulated, LPS, IgA prot

c:dorms, prisons, military, joints, mening,

t:pen g, NO GLUCOCORT

p:vacc

Term
n. gonorrheae
Definition

d:g-diplococci, noncapsule, LOS, ox+

v:pili, porin, Opa, ab resist

c:fitz-hugh-curtis- fallopian tube->liver, dissem:arth/derm, rare mening/endocard, bilateral conj in neonates

t: ceft,

p:neonate proph, reporting,

Term
cornybacteria diptheriae
Definition

d:g+rod, v/l, metachrom granules, tellurite media

v:diptheria toxin

r:mucouos memb

c:ulcer, grey/brown pseudomembrane, tonsils/phary, toxin- mycard, per neuro, kidney, thrombocytop

t:equine antitox, penG or erythro

p:vacc

Term
listeria monocytogenes
Definition

d:g-rod, fac-an, blue-green on blood, v/l, tumbling, b-hemo

v:cold, intracellular, ActA, listerolysin-escapes vacuole

c:preterm abortion, neon seps, cns

t:amp, gent

p:report, food hyg

Term
mycoplasma pneumoniae
Definition

d:small, aerob, no wall,

v:P1 adhesin, CARDS exotox, intra possible,

c:walking pneum, inhaled, bad xray,

t:fluoroqu covers all similar pneum, macrolides better,

Term
pseudomonas aeruginosa
Definition

d:g-rod, aer, ox+, nonferm, pyocyanin/verdin, slime, TSI metallic sheen,

v:minimal reqs, ab/disinfect resis, endo, exoA, ttss, elastase, protease, pyocy-inh electron chain

c:immunosup, burns, cf, osteocondritis, UTI, surg inf, corn, endocard (iv drug), brain absc, pneumo,

t:ab sens, combinations

p:hygiene

Term
burkholderia cepacia
Definition

d:g-rod, no color

v:low, ab resistance

c:immunosuppr, pneumo in cf centers

t:trim-sulf, ceph, cipro, meorpenam,

p:exp vacc

Term
burkholderia pseudomallei
Definition

d:motile,

r:env, water soil,

 

c:melioidosis-flulike, muscle tightness, light sens, abscesses in all organs, reactivation

t:certazidime, or w/trim-sulf, or amox

p:report-biowar

 

Term
burkholderia mallei
Definition

d:non-motile

c:glanders, flu-like

v:pyocyanin, lecithinase, collagenase, lipase, hemolysin, chronic-farcy

p:reportable-biowarfare

t:amox+clavulanate, doxy,trim-sulf

Term
campylobacter
Definition

jejuni, coli, fetus

d:ox+, curved g-rods, selective agar, capnophilic, thermophilic

r:poultry

v:direct invasion,

c:gastroent maybe blood, gullain-barre-paralysis of per nerves, LOS ab reaction; reactivie arthritis

t:macrolides, cipro

Term
helicobacter pylori
Definition

d:g-curved rods, stool antigen

v:urease, flagella, acid inh protein, vaculating cytotoxin,

t:ppi+clarithro/metronidazole

 

Term
vibrio
Definition

cholera: O1 serovar

 

parahemolyticus-sushi

alginolyticus/vulnificus-wound infections, saltwater

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