Term
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Definition
study of biological function |
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Definition
specific range for body temp, blood sugar, tension on a tendon, etc. |
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Definition
Particular muscles or glands that regulate the body back to its set point |
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Definition
Receives information from many different sensors that increases or decreases effector activity |
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Definition
Negative or reverse regulation that lowers the level of deviation from the set point (air conditioner in house) |
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Definition
action of effectors amplifies those changes that stimulated the effectors (ex. Thermostat increases heat production in response to rise in temperature) |
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Definition
"Built-in" to the organs being regulated |
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Definition
Regulation of an organ by the nervous and endocrine systems |
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Definition
chemical regulators in the body |
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Definition
Specific organs that respond to a particular hormone |
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Definition
Tissue specialized for contraction |
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Term
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Definition
tissue generally attached to bones at both ends by means of tendons
Contractions produce movements of the skeleton
Myofibers
STRIATED- Gradient of strength of contraction |
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Term
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Definition
Muscle is only found in the heart
Myocardial cells
Intercalated discs
"Whole-hearted" contraction Stimulation of one cell stimulates an entire mass |
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Term
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Definition
short, branched, intimately connected muscle cells that form a continuous fabric |
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Term
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Definition
Muscle tissue found in the digestive tract, blood vessles, bronchioles, ducts of urinary and reprod. systems
No STRIATIONS |
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Definition
Tissue that consists of neurons and supporting cells |
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Term
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Definition
Nerve cells
Generate and conduct electrical signals and events |
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Term
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Definition
Glial cells
Provide neurons with anatomical and functional support |
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Term
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Definition
Tissue that forms membranes that cover and line body surfaces and glands |
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Term
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Definition
Secrete chemicals through a duct that leads to the outside of a membrane and to the outside of the body surface |
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Term
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Definition
Secrete hormones into the blood |
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Term
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Definition
Tissue specialized for contraction |
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Term
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Definition
tissue generally attached to bones at both ends by means of tendons
Contractions produce movements of the skeleton
Myofibers
STRIATED- Gradient of strength of contraction |
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Term
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Definition
Muscle is only found in the heart
Myocardial cells
Intercalated discs
"Whole-hearted" contraction Stimulation of one cell stimulates an entire mass |
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Term
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Definition
short, branched, intimately connected muscle cells that form a continuous fabric |
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Term
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Definition
Muscle tissue found in the digestive tract, blood vessles, bronchioles, ducts of urinary and reprod. systems
No STRIATIONS |
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Term
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Definition
Tissue that consists of neurons and supporting cells |
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Term
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Definition
Nerve cells
Generate and conduct electrical signals and events |
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Term
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Definition
Glial cells
Provide neurons with anatomical and functional support |
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Term
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Definition
Tissue that forms membranes that cover and line body surfaces and glands |
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Term
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Definition
Secrete chemicals through a duct that leads to the outside of a membrane and to the outside of the body surface |
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Term
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Definition
Secrete hormones into the blood |
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Term
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Definition
epithelial membranes only one cell layer thick |
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Term
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Definition
epithelial membranes composed of a number of cell layers |
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Term
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Definition
epithelial cells that are flattened |
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Term
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Definition
epithelial tissues that are as wide as they are tall |
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Term
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Definition
epithelial tissues that are taller than they are wide |
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Term
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Definition
Tissue that has large amounts of extracellular material in the spaces between the tissue's cells |
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Term
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Definition
Loose connective tissue collagen dense fibrous connective tissue |
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Term
What is found in the nucleus of an atom? |
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Definition
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Term
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Definition
Two structures with identical molecular formula, but different structures/characteristics |
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Term
What determines the Atomic Number |
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Definition
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Term
What determines the Atomic Mass of an element |
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Definition
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Term
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Definition
Group of atoms bonded together |
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Term
How do covalent bonds form? |
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Definition
Atoms of a molecule share electrons |
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Term
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Definition
Atoms share electrons equally |
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Term
Examples of non-polar molecules |
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Definition
CO2, CCL4, Oxygen, Lipids |
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Term
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Definition
Insoluble in water (Non-polar molecules) |
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Term
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Definition
Cation (+) bonds with anions (-) |
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Term
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Definition
Electrons create a polarity (unequal sharing of electrons) across molecule |
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Term
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Definition
Unequal sharing of electrons |
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Term
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Definition
All body fluid inside cells |
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Term
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Definition
All fluid outside of the cell |
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Term
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Definition
G0 (Cells have stopped dividing) |
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Term
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Definition
Checkpoint Protein Needs to be in high levels of concentration to move cell into S phase (similar to protein kinases) |
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Definition
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Term
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Definition
Haploid cells (23 chromosomes) Gametes Crossing Over (prophase I) Metaphase I Telephase I lacks homologous chromosomes |
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Term
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Definition
Cell stage Only stage not in interphase |
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Definition
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Definition
Organizing center for tubulin (microtubules) |
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Term
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Definition
Spindle fibers attach to chromosome |
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Definition
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Definition
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Definition
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Definition
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Definition
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Term
4 chromatid Homologous chromosomes |
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Definition
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Term
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Definition
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Term
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Definition
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Term
Chromosomes align along mid-line of cell |
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Definition
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Term
Centromere splits Chromosomes separate |
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Definition
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Term
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Definition
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Term
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Definition
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Definition
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Term
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Definition
Location of gene on a chromosome |
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Definition
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Term
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Definition
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Definition
47
Ex: Trisomy X, two barr bodies |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Many genes cause phenotype |
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Term
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Definition
Heterozygous has blended phenotype |
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Term
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Definition
HOX(homeotic) genes also found in mice with new ones added. Shows how evolution works. (fruit fly to a mouse)
Master Control Genes - Control placement of parts of embryo but not specifics of what part looks like. |
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Term
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Definition
Mouse eye gene+ fruitfly= Compound fruitfly eye |
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Term
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Definition
"Above Genetics" Heritable change but not DNA base change Not a mutation |
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Term
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Definition
CH3 (methyl) attached to specific regions of DNA to block transcription -Pattern changes with aging and stress |
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Term
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Definition
Changes in histone tails -Make chromosomes more or less compact -Activate or reduce transcription -patterns change with stress, drug addiciton |
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Term
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Definition
Control ability of mRNA to be read (block transcription-Good drug manufacture)
Plays role in cancer and inactivation chromosome |
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Term
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Definition
proteins that control transcription by binding to Promoter -Signal RNA polymerase to bind and transcribe mRNA |
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Term
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Definition
Put mRNA for Bicoid in egg -Mother determines gradient |
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Term
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Definition
sets up axis (head and tail) |
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Term
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Definition
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Term
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Definition
Master transcription factors that ativate genes in each segment (colinear)
Activate genes is segment |
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Term
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Definition
cell becomes a type by its position in the developing organism |
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Term
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Definition
Gradients of sinals/proteins/morphagens |
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Term
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Definition
material in egg from mothers genome sets stage for development |
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Term
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Definition
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Term
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Definition
developed twoard a specific cell type |
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Term
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Definition
capable of developing in many cell types |
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Term
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Definition
Can become all cell types + Placenta |
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Term
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Definition
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Definition
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Term
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Definition
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Term
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Definition
Induced Pleuipotent Stem cells
Can be made from adult cells with 4 genes added |
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Term
Higher Maternal age means.... |
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Definition
Higher chance of trisomys |
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Term
Four Types of Macromolecules |
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Definition
Carbohydrates Lipids Proteins Fats |
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Term
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Definition
large molecules from smaller subunits |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Formation of macromolecules by the removal of water (monomer to polymer) |
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Term
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Definition
Breaking down with water (polymer to monomer) |
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Term
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Definition
monomer of sugars 5 or 6 carbons |
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Term
Ring or Linear structures |
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Definition
Different ways to show the structure |
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Term
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Definition
Two structures with an identical molecular formula but different structures an |
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Term
3 types of structural isomers |
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Definition
Structural Isomer Stereoisomer Enantiomers |
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Term
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Definition
Different arragement of around same elements Ex: Glucose, galactose, fructose |
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Term
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Definition
Geometric Isomers -Above or Below Ring -Ex: a-B Glucose |
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Term
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Definition
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Term
|
Definition
Carbohydrates composed of TWO MONOSACCHARIDES -Ex: Sucrose = glucose+frutose |
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Term
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Definition
Long chains of sugars Energy Storage Strutural support: Cellulose, Chitin |
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Term
Higher Branching Carbohydrate |
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Definition
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Term
Examples of Polysaccharides |
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Definition
Starch, Glycogen, Cellulose |
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Term
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Definition
Carbohydrate polymer that makes up exoskeletons of insects |
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Term
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Definition
Carbohydrate polymer that makes up plant stems |
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Term
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Definition
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Term
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Definition
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Term
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Definition
Basis for all organic molecules |
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Term
Atributes of Living Things |
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Definition
Metabolism Reproduction Sense Environment and Respond Develop\Grow |
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Term
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Definition
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|
Term
Two Types of carbohydrates |
|
Definition
Pento- 5 Carbon C5H20
Hexo- 6 Carbon C6H20 |
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Term
What Disaccharide can be made from starch? |
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Definition
High Frutose Corn Syrup (HFCS) Contain glucose and frutose monomers |
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Term
Does more branching make polysaccharides easier or harder to digest? |
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Definition
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Term
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Definition
-Modified sugars (glucosamine) - Used for structures (chitin) |
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Term
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Definition
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Term
|
Definition
Fats Phospholipids Steroids |
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Term
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Definition
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Term
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Definition
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|
Term
Structure of Steriods/Cholesterol |
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Definition
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Term
|
Definition
Monomers of Fats and Phosopholipids Long Hydrocarbon chains - Made of mostly C and H -Have C (carboxly end) and omega end |
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Term
|
Definition
Covalent (polar and non-polar) Ionic Hydrogen |
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Term
|
Definition
Electrons create a polarity across molecule |
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Term
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Definition
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Term
|
Definition
Cations (+) bond with Anions (-) |
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Term
|
Definition
H atom in a molecule becomes attracted to a O or N atom in another polar molecule |
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Term
|
Definition
Water Loving Attracted to Water |
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Term
|
Definition
Water Fearing Repels away from H20 |
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Term
Polar and Ions Hydrophillic or Hydrophobic |
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Definition
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|
Term
Non polar Hydrophillic or Hydrophobic |
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Definition
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Term
|
Definition
gradient of acidic to basic of solutions |
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Term
|
Definition
The concentration of H+ ions to OH- ions |
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Term
|
Definition
Makes solution more acidic |
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Term
|
Definition
Makes solution more basic |
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Term
|
Definition
-No double H bonds -All carbons are linked by single covalent bonds -Tend to be solid at room temp |
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Term
|
Definition
-one or more double H bonds -Tend to be a liquid at room temp |
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Term
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Definition
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Term
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Definition
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Term
|
Definition
3 carbons after double H bond in tails
Ex: c=c-c-c |
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Term
|
Definition
6 carbons after double H bond in tails
Ex: c=c-c-c-c-c-c |
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|
Term
More carbons in fatty acids makes melting point... |
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Definition
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Term
|
Definition
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|
Term
Unsaturated melting point |
|
Definition
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Term
|
Definition
Trans strucutre in fatty acid tail H | C=C | H |
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|
Term
Omega-3 fatty acids found in fish |
|
Definition
EPA (20 carbon) DHA (22 carbon) Needed for growth and repair To make other fatty acids |
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Term
|
Definition
Made from 3 fatty acids attached to glycerol (by dehydration synthesis) -Ester Bond |
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Term
|
Definition
Fatty acids are NOT a fat |
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Term
|
Definition
1 gram of fat stores 2x as much energy as 1 gram of glycogen or starch |
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|
Term
How do we get monosaturatd fats |
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Definition
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|
Term
How do we get polysaturated fats |
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Definition
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Term
|
Definition
Glycerol + 2 fatty acids + a phosphate group (Amphiphilic- part polar) -Form lipid bilayers |
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Term
|
Definition
Interconnected rings of carbons Hydrophobic Cholesterol Hormones (estrogen, testoserone) Not used as monomers |
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Term
|
Definition
monomer: Amino Acid (20 types) |
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Term
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Definition
differ by group -some hydrophobic -acidic -basic -neutral |
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Term
Primary Structure (peptide) |
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Definition
list (sequence) of amino acids in peptide |
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|
Term
Secondary Structure (peptide) |
|
Definition
Folding based on hydrogen bonds (non-R group) -Helical, pleated sheet, random |
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|
Term
Tertiary Structure (peptide) |
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Definition
3-D folding based on R-groups -Helical, globular |
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|
Term
Quaternary Structure (peptide) |
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Definition
2 or more peptides non-covalent bonding |
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Term
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Definition
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Term
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Definition
|
|
Term
Structural Proteins structure |
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Definition
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Term
|
Definition
Unfolding of peptide due to environmental conditions Ex: egg on frying pan |
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Term
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Definition
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Term
|
Definition
monomer of nucleic acids responsible for energy storage, cell signalling, transmition of genetic info -Base+ 5 carbon sugar+ phosphate |
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Term
|
Definition
Polymer of nucleic acids Sugar is Ribose |
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Term
|
Definition
Polymer of nucleic acids sugar is deoxyribose (no oxygen) |
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Term
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Definition
-All organisims are composed of living cells -Cells are the smallest living things -Cells arise from pre-existing cells |
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Term
|
Definition
Genetic Material Cytosol Plasma Membrane |
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Term
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Definition
No nucleus Appendeges- Pili, Flagella DNA in nucleoid region No membrane bound organelles |
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Term
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Definition
Nucleus DNA inside nucleus Cytosol Nucleus Membrane bound organelles |
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Term
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Definition
in cytosol can move around anywhere Proteins are released in cytosol |
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Term
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Definition
rER bound Synthesize proteins used by rER |
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Term
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Definition
Synthesize protein chains |
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Term
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Definition
entirety of organism's heriditary info DNA or RNA Gene Sequence |
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Term
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Definition
Entire set of proteins expressed by a genome Protein set |
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Term
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Definition
-Nucleus -Mitochondria -Chloroplast (plant only) |
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Term
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Definition
Converts Peroxide into water uses enzyme Catalase |
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Term
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Definition
Phospholipid bilayer -Impermeable (Ions, polar molecules) -Permeable (non-polar molecules) |
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Term
|
Definition
Protein that is permanently attached to the cell membrane |
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Term
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Definition
span all the way through the membrane |
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|
Term
Peripheral Membrane Protein |
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Definition
-Attached on surface, easy to remove |
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Term
|
Definition
can see: -Mitochondria -Most bateria -Most plant and animal cells |
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Term
|
Definition
Can see: -viruses -small bacteria -ribosomes -proteins -lipids |
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|
Term
Why is cell membrane called fluid mosiac? |
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Definition
Mosiac because its a MIX of lipids and proteins
Fluid because bilayer is like a light oil. Proteins and lipids can move around plane but always come back to same position |
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|
Term
What does cholesterol do to the cell membrane |
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Definition
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|
Term
What happens if the membrane becomes too hot? |
|
Definition
|
|
Term
What happens if the membrane becomes too loose? |
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Definition
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Term
|
Definition
chain of sugars attached to a protein |
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Term
|
Definition
Markers (recognition site)
One or more sugars attached to the Polar end of the lipid |
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Term
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Definition
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Term
|
Definition
-small non-charged, NON POLAR gases, ethanol
Requires no energy (ATP) |
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Term
|
Definition
-Facilitated (needs integral protein) - High to Low concentration |
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Term
|
Definition
Diffusion of water across membrane |
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Term
|
Definition
Equal water and soulute concentration on either side of membrane |
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Term
|
Definition
Solute concentration is higher Water concentration is lower Cell shrinks
Water goes out of cell to dilute the solute |
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Term
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Definition
Solute concentration is lower Water concentration is higher
Cell gets larger, water comes in to dillute solute |
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Term
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Definition
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Term
|
Definition
Movement of a substance AGAINST its concentration gradient
Requires ATP or other energy
Pump (low to high) |
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Term
|
Definition
Distribution of solute from high to low concentration |
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|
Term
Two types of Gradients (transport) |
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Definition
Transmembrane Gradient Ionic electrochemical gradient |
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Term
|
Definition
Concentration of a solute is higher on one side of the membrane than the other |
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|
Term
Ionic Electrochemical gradient |
|
Definition
Both an electrical gradient (charge) and chemical gradient |
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Term
|
Definition
Help maintain resting potential
Regulates cellular volume
Action potential for neurons |
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Term
|
Definition
Endocytosis Phagocytosis Pinnocytosis |
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Term
|
Definition
Vesicle pinches off of plasma membrane and into cell |
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Term
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Definition
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Term
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Definition
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Term
|
Definition
Material to be imported attaches to binding protein that concentrates it.
Specific molecules only |
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Term
|
Definition
Vesicle fuses with plasma membrane
Vesicle content going OUTSIDE |
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Term
|
Definition
Post Office Sorts proteins into vesicles Protein Modifacation
Enzymes in golgi mark proteins Cis, Trans, Cisternae |
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Term
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Definition
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Term
|
Definition
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Term
|
Definition
Site for steriods detox and Calcium storage |
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Term
|
Definition
protein synthesis ribosomes |
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Term
|
Definition
Digestion in cell Come from Golgi |
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Term
|
Definition
Protein synthesis on free ribosomes Ribosomes bind to rER--> signal peptide Completed protein is inside rER, go to golgi visicles break off of golgi, become cis face lysosomes or for exocytosis Exocytosis replaces plasma membrane |
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Term
|
Definition
Amount of energy change in a RXN Amount of energy for work (free energy) |
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Term
|
Definition
Favorable Delta G is negative (extra energy) |
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|
Term
Not Spontaneous (endergonic) |
|
Definition
Not Favorable Delta G is positive (needs extra energy) |
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Term
|
Definition
Overall Change is negative Endergonic + Exergonic =exergonic Make reactions easier for cell |
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Term
|
Definition
LEO Loss of Electrons Reductant--> Product + electron Electron lost |
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Term
|
Definition
GEO Gain of Electrons Oxidant + Electron = Product Electron gained |
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Term
|
Definition
Proteins that catalyze (increase rates of) reactions Bind substrates |
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Term
|
Definition
Primary space that binds substrates |
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Term
|
Definition
Non protein molecules
Required to bind to enzymes to make them active
Usually temporary |
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|
Term
Read about Cellular Respiration |
|
Definition
|
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Term
|
Definition
Glucose (6C) to 2 pyruvate(3c)
Net 2 ATP 2 NADH 2 pyruvate |
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
Where does glycolysis happen |
|
Definition
|
|
Term
Where does pyruvate breakdown occur |
|
Definition
|
|
Term
Oxydative Phosphorylation |
|
Definition
Aerobic oxidation of NADH, makes ATP Reduction of oxygen Phosphorylation occurs by ATP synthase |
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Term
|
Definition
|
|
Term
Overview of Cell Respiration |
|
Definition
C6H12+6O2 to 6CO2+6H20
Coupled to e- stored in 10 NADH and 2FADH2
Coupled to phosphylation of 2 ATP and 2 GTP
No oxygen required in Kreb cycle
Oxygen required in everything else |
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Term
|
Definition
Substrate-level phosphorylation
Energy stored in electrochemical gradient |
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|
Term
Substrate level phosphorylation |
|
Definition
Enzyme directly transfers phosphate |
|
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Term
|
Definition
energy stored in it makes ATP from ADP and P |
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Term
|
Definition
Outer membrane Inner membrane Matrix Cristae Inner membrane space
Double Membrane
Comes from Mother |
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Term
|
Definition
|
|
Term
|
Definition
Oxygen Free Radicals -Parkinsons -Cardiac Damage -Diabetes |
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|
Term
|
Definition
in inner membrane of mitochondria
Protons increase in inner & outer membrane |
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Term
|
Definition
Double Membrane -Outer and Inner
Thaylakoid -has chrlorphyll -3rd membrane |
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Term
|
Definition
Fluid part
Has DNA, ribosome
Semi-Automous |
|
|
Term
Photosynthesis takes place in |
|
Definition
|
|
Term
|
Definition
Photosystem II Oxygen from water Electron trans + H gradient makes ATP |
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Term
|
Definition
Photosystem I Electrons for NADPH |
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Term
|
Definition
|
|
Term
|
Definition
Flow of Electrons and photons (light reaction) |
|
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Term
|
Definition
CO2 fixation
2 (3C)use ATP+ NADPH in Stroma to put CO2 into organic molcules |
|
|
Term
|
Definition
carbon dioxcide plus water reacts to light to make glucose and oxygen |
|
|
Term
Calvin Cycle ATP is Added NADPH is Added What is released |
|
Definition
ADP is released NADP is released |
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Term
|
Definition
Sending and receiving molecules |
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Term
|
Definition
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Term
|
Definition
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|
Term
|
Definition
|
|
Term
|
Definition
unique 3D space to bind to Ligand No catalytic activity, just releases ligand |
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Term
|
Definition
Transmembrane proteins Change shape when Ligand binds |
|
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Term
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Definition
Opens channel add Phosphate to proteins activate G proteins |
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How are cellular actions in Eukaryotes controlled |
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Activated receptor sets off transduction pathway
protein kinases
G proteins
Second messengers |
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Add phosphate to other proteins activate other proteins
Amplifies signal |
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Activation of transcription factor |
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cause GTP to bind to G proteins
Start amplifacation |
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small molecules activate various reactions in the cell amplify signal of receptor binding |
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additions or deletions to sequence |
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reproductive cells eggs and sperm |
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Controls what genes are replicated |
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3 components of nucleotides |
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Definition
Phosphate Sugar Ribose Deoxyribose Nitrogenous bases |
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Cytosine Thymine or Uracil |
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A binds T, G binds C in DNA (AT, GC) A binds U, G binds C in RNA (AU, GC) |
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3 components of nucleotides |
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Definition
Phosphate Sugar Nitrogenous bases |
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Cytosine Thymine or Uracil |
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Antiparallel structure of DNA |
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Definition
one strand 5' to 3' other 3' to 5' |
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single double stranded DNA+Protein |
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150 bp of DNA Wraps around 4 histone molecules 7x compact |
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Linker regions Between nucleosome looped together |
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Where DNA begins to unwind Open up forks |
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Small piece of single stranded DNA or RNA
Needed to start replication |
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New strand is made _' to _' |
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Definition
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Template strand is _' to _' |
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Fragments of replicated DNA from lagging strand in fork |
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End of Eukaryotic chromosomes Get shorter each division (age) |
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connects inner and outer nuclear membrane
Controls materials going in and out |
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Protein coating inside of inner membrane
Chromosomes attach to it |
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binds to promoter before transcription |
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Pre-mRNA processed/spliced when? |
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5' cap Poly A tail (AAAAA) |
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transport carries amino acids
in cytoplasm
Correct amino acid at the top |
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ribosomal part of ribosomes |
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Definition
messenger carries code for genes |
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needs pre-mRNA to splice it into smaller functional mRNA Get it out of nucleus |
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Anticodon is bases in ______. |
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Definition
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Codons and Anticodons have how many bases in a row? |
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more than one codon each amino acid |
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First two bases are more important than 3rd |
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Only start and stop signals Have to start at correct place to make correct peptide |
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Small subunit binds to mRNA AUG codon First tRNA anticodon
Large subunit binds to 3 sites P site A site E site |
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New activated amino actyl tRNA Enters A site Binds codon/anticodon |
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one condon, peptide, back in P site |
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elongation continues until stop codon |
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Prokaryotes gene regulation |
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How many promoters in operon model |
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How many genes does a promoter control? |
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Definition
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Term
Repressor I proteins bind to ______ region to _______ |
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Definition
O region
Stop transcription |
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Term
Eukaryotes gene regulation |
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Definition
Each cell has same genome only some genes transcribed |
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Definition
proteins that activate transcription |
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turns on genes for transcription controls multiple genes |
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Alterations in histones can..... |
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Definition
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smalls RNAs that block translation |
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