Term
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Definition
Promotes vasodilation primarily on veins and modestly on arterioles. Thus it decreases both preload and afterload.
Used for stable and variant angina
S/E: hypotension, reflex tachycardia, and H/A |
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Term
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Definition
" - LOL" Metoprolol
Decreases HR and contractility.
A slower HR increases time in diastole => heart spends more time resting and blood spends more time in cardiac vessels.
Affects afterload |
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Term
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Definition
Nifedipine, Diltiazem, Verapamil
Block calcium channels in arterioles = Dec. Afterload
Blocks Ca++ in myocardium = Dec. HR, conduction, contractility
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Term
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Definition
Morphine
Oxygen Supplement
Nitroglycerin
Aspirin |
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Term
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Definition
| Muscarininc antagonist (anticholinergic): increases HR, used for bradycardia |
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Term
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Definition
| Diuretic used for long term therapy of HF. Ineffective if GFR low. Does not spare potassium. |
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Term
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Definition
| High Ceiling Loop Diuretic: produces profound diuresis and can promote fluid loss even with low GFR. Does not spare potassium. |
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Term
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Definition
| Potassium Sparing Diuretic: promotes only scant diuresis. Offsets potassium loss caused by furosemide and HTZ. |
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Term
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Definition
"- PRIL"
Improve function of heart and prolong life. Blocks production of angiotensin II, decreases release of aldosterone, and suppresses degradation of kinins. |
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Term
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Definition
| Inotropic Agents: activate beta1 adrenergic receptors thus increasing myocardial contractility and thus myocardial performance. |
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Term
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Definition
Cardiac Glycoside: increases myocardial contractility, thus increasing CO. Does not prolong life.
NARROW THERAPEUTIC RANGE: serum potassium levels must be kept within normal range. |
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Term
Class I Antidysrhythmics:
Sodium Channel Blockers
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Definition
| Quinidine and Lidocaine: blocks sodium channels thus slowing conduction velocity in heart and delaying repolarization. Used for supraventricular and ventricular dysrhythmias |
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Term
Class II Antidysrhythmics:
Beta Blockers |
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Definition
| Metoprolol: Bloocs cardiac Beta 1 receptors resulting in decreased automaticity of SA node, and decreased conduction through AV node. Decreases myocardial contractility. Used for tachycardia and other dysrhythmias d/t excessive SNS stimulation |
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Term
Class III Antidysrhthmias:
Potassium Channel Blockers |
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Definition
| Amiodarone: delays repolarization. May reduce automaticity in SA node, decrease contractility, and decrease conduction in AV node. |
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Term
Class IV Antidysrhythmias:
Calcium Channel Blockers |
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Definition
Slow SA node automaticity, delay AV node conduction and reduce myocardial contractility.
Important NOTE: Only diltiazem & verapamil used for dysrhythmias! The "-dipines" are used for vasodilatory effects to ↓cardiac workload or ↓BP |
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Term
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Definition
Decreases automaticity in SA node and slows conduction through AV node.
Used ONLY for paroxysmal SVT. Not effective against A-fib/flutter or VD.
Half life < 1 minute |
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Term
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Definition
| Causes selective dilation of arterioles, thus decreasing afterload. |
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Term
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Definition
| Anticoagulant: reduces formation of fibrin. Most effective against arterial thrombosis. |
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Term
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Definition
| Antiplatelet: prevents platelets from aggregating to form clots. Most effective against venous thrombosis. |
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Term
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Definition
| Thrombolytics: promote lysis of fibrin, thus causing dissolution of thrombi |
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